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DiffuScope: A diffusion-regularized autoencoder for spatial transcriptomic clustering

delete2025-10-24
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PRE
AI
H
Hua Shi
丁轶 (Yi Ding)
Y
Yang Cui
R
Ruheng Wang
李燕 cover
李燕 (Yan Li)
C
Chunyan Ao
R
Ruihua Guo
W
Weihang Zhang
T
Tao Peng
Y
Yuying Le *
Y
Yaxuan Cui *
L
Leyi Wei *
DOI:10.1016/j.compbiolchem.2025.108746delete
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Abstract

Abstract

En 中文
• DiffuScope integrates graph autoencoders with diffusion loss for spatial clustering. • Achieves robust and accurate performance across diverse spatial transcriptomic datasets. • Reveals biologically meaningful domains in gastric and breast cancer tissues.

Journal

C
Computational Biology and Chemistry
IF:
3.1
Papers:
390
Citations:
0

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U
University of Tokyo
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