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Digital Microfluidics

delete2012-07-19
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PRE
AI
K
Kihwan Choi *
A
Alphonsus H. C. Ng
R
Ryan Fobel
A
Aaron R. Wheeler
DOI:10.1146/annurev-anchem-062011-143028delete
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Abstract

Abstract

En 中文
Digital microfluidics (DMF) is an emerging liquid-handling technology that enables individual control over droplets on an open array of electrodes. These picoliter- to microliter-sized droplets, each serving as an isolated vessel for chemical processes, can be made to move, merge, split, and dispense from reservoirs. Because of its unique advantages, including simple instrumentation, flexible device geometry, and easy coupling with other technologies, DMF is being applied to a wide range of fields. In this review, we summarize the state of the art of DMF technology from the perspective of analytical chemistry in sections describing the theory of droplet actuation, device fabrication and integration, and applications.
Keywords:
droplet
electrowetting on dielectric
dielectrophoresis
diagnosis
proteomics
bioanalysis

Journal

Annual Review of Analytical Chemistry cover
Annual Review of Analytical Chemistry
IF:
7.5
Papers:
394
Citations:
2.7K

Organization

U
university of toronto
Scholars:
14.8W
Papers: 12.0W
Citations: 165
Cited Papers

Cited Papers

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Stick and slide ferrofluidic droplets on superhydrophobic surfaces
err2006-08-24
err139
PREAI
errGuo, Zhi-Guang; Zhou, Feng; Hao, Jing-Cheng; Liang, Yong-Min; Liu, Wei-Min; Huck, Wilhelm T. S.
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On-Chip Drop-to-Drop Liquid Microextraction Coupled with Real-Time Concentration Monitoring Technique
err2011-02-04
err87
PREAI
errWijethunga, Pavithra A. L.; Nanayakkara, Yasith S.; Kunchala, Praveen; Armstrong, Daniel W.; Moon, Hyejin
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A Digital Microfluidic Approach to Proteomic Sample Processing
err2009-05-06
err128
errOAAI
errLuk, Vivienne N.; Wheeler, Aaron R.
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Droplet-Scale Estrogen Assays in Breast Tissue, Blood, and Serum
err2009-10-07
err134
PREAI
errMousa, Noha A.; Jebrail, Mais J.; Yang, Hao; Abdelgawad, Mohamed; Metalnikov, Pavel; Chen, Jian; Wheeler, Aaron R.; Casper, Robert F.
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All-terrain droplet actuation
err2008-01-01
err221
PREAI
errAbdelgawad, Mohamed; Freire, Sergio L. S.; Yang, Hao; Wheeler, Aaron R.
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