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Digital Microfluidics
DOI:10.1146/annurev-anchem-062011-143028.png)
Abstract
En 中文
Digital microfluidics (DMF) is an emerging liquid-handling technology that enables individual control over droplets on an open array of electrodes. These picoliter- to microliter-sized droplets, each serving as an isolated vessel for chemical processes, can be made to move, merge, split, and dispense from reservoirs. Because of its unique advantages, including simple instrumentation, flexible device geometry, and easy coupling with other technologies, DMF is being applied to a wide range of fields. In this review, we summarize the state of the art of DMF technology from the perspective of analytical chemistry in sections describing the theory of droplet actuation, device fabrication and integration, and applications.
Keywords:
droplet
electrowetting on dielectric
dielectrophoresis
diagnosis
proteomics
bioanalysis
Journal
IF:
7.5
Papers:
394
Citations:
2.7K
Organization
Cited Papers
An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids
LAB ON A CHIP
IF5.4
Preventing biomolecular adsorption in electrowetting-based biofluidic chips
ANALYTICAL CHEMISTRY
IF6.7
Multilayer Hybrid Microfluidics: A Digital-to-Channel Interface for Sample Processing and Separations
ANALYTICAL CHEMISTRY
IF6.7
On-Chip Drop-to-Drop Liquid Microextraction Coupled with Real-Time Concentration Monitoring Technique
ANALYTICAL CHEMISTRY
IF6.7

