.png){kind=icon}
.png){kind=icon}
Return
Exploring the antibacterial mechanism of Perilla essential oil based on network pharmacology and molecular dynamics techniques
.png){kind=icon}
OA
AI
张
J
B
Y
T
Y
DOI：10.1016/j.jfca.2026.109321.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• A novel “membrane-metabolism-DNA” triple-action mechanism of Perilla essential oil (PEO) against Bacillus species is revealed for the first time. • Network pharmacology identifies 17 key components in PEO targeting 50 core proteins, including PTGS2, CYP3A4, and CYP2C19. • Integrated 100-ns molecular dynamics simulations confirm stable binding and reveal van der Waals forces as the dominant interaction.
Keywords:
Perilla essential oil
Bacillus subtilis
Bacillus cereus
Antibacterial mechanism
Membrane disruption
DNA damage
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
4.6
Papers:
7.5K
Citations:
1.9W
Organization
Cited Papers