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Generative Biomedical Event Extraction With Constrained Decoding Strategy
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AI
DOI：10.1109/TCBB.2024.3480088.png)
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Abstract
En 中文
Currently, biomedical event extraction has received considerable attention in various fields, including natural language processing, bioinformatics, and computational biomedicine. This has led to the emergence of numerous machine learning and deep learning models that have been proposed and applied to tackle this complex task. While existing models typically adopt an extraction-based approach, which requires breaking down the extraction of biomedical events into multiple subtasks for sequential processing, making it prone to cascading errors. This paper presents a novel approach by constructing a biomedical event generation model based on the framework of the pre-trained language model T5. We employ a sequence-to-sequence generation paradigm to obtain events, the model utilizes constrained decoding algorithm to guide sequence generation, and a curriculum learning algorithm for efficient model learning. To demonstrate the effectiveness of our model, we evaluate it on two public benchmark datasets, Genia 2011 and Genia 2013. Our model achieves superior performance, illustrating the effectiveness of generative modeling of biomedical events.
Keywords:
Biological system modeling
Decoding
Regulation
Computational modeling
Semantics
Vectors
Transformers
Proteins
Protein engineering
Adaptation models
Biomedical event extraction
constrained decoding
generative models
Journal
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3.4
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3.3K
Citations:
6.4K