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High content cellular screening
DOI:10.1016/j.cbpa.2006.06.004.png)
Abstract
En 中文
Over the past few years, high content screening has firmly established itself as a high-throughput technology for the analysis of microscopy-based cellular assays. In particular, it has opened new areas of cell biology for the large-scale analysis of cellular phenotypes and has enabled the application of increasingly sophisticated assays for large-scale genetic and compound screening, benefiting both the academic and pharmaceutical research environment.
Keywords:
COUPLED RECEPTOR DESENSITIZATION
HIGH-CONTENT ASSAYS
DRUG DISCOVERY
MAMMALIAN-CELLS
VALIDATION
KINASES
PATHWAY
BIOLOGY
SYSTEM
RNAI
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