High glucose is associated with thermotolerance and better maintenance of mitochondrial polarization in Cyberlindnera fabianii under heat stress

Quan Liu

doi:10.1016/j.fm.2026.105187

High glucose is associated with thermotolerance and better maintenance of mitochondrial polarization in Cyberlindnera fabianii under heat stress

2026-06-02

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AI

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Quan Liu

C

Chunyue Yan

X

Xiong Xiao

X

Xiong Chen *

X

Xin Li *

DOI：10.1016/j.fm.2026.105187

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• Cyberlindnera fabianii survived 45 °C heat shock better than S. cerevisiae. • High glucose maintained culturability and mitochondrial polarization at 45 °C. • Low glucose repressed central carbon metabolism under heat stress. • High glucose attenuated mitochondrial quality-control responses to heat. • Xylose or glycerol co-feeding supported heat-stress culturability.

High glucose is associated with thermotolerance and better maintenance of mitochondrial polarization in Cyberlindnera fabianii under heat stress

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