.png){kind=icon}
.png){kind=icon}
Return
In vivo imaging of lipid nanoparticle messenger RNA therapeutics: Current advances and emerging opportunities
.png){kind=icon}
PRE
AI
N
DOI：10.1016/j.ejmech.2026.119213.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• In vivo imaging maps medicine biodistribution and organ-specific uptake. • Imaging can quantify cellular entry and endosomal escape of mRNA vaccines. • Real-time tracking reveals intracellular trafficking kinetics. • Multimodal imaging allows to link tropism with functional mRNA expression. • In vivo imaging enables mechanism-driven optimization of mRNA vaccine design.
Keywords:
mRNA therapeutics
Lipid nanoparticle (LNP)
In vivo imaging
Biodistribution
Endosomal escape
Translation efficiency
Rational design
Vaccine development
Ionizable lipid
Journal
IF:
5.9
Papers:
1.7W
Citations:
6.0W
Organization
No organization information available
Cited Papers