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European Journal of Medicinal Chemistry cover

European Journal of Medicinal Chemistry

IF5.9
Papers16629
Citations59745
Journal Papers 16550
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In vivo imaging of lipid nanoparticle messenger RNA therapeutics: Current advances and emerging opportunities
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-08-04
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deleteNatacha Jugniot
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Troxerutin as a bioactive flavonoid: Insights into its anticancer mechanisms and therapeutic applications
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-23
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deleteManna, Priya; Chatterjee, Srijita; Ganguly, Shayeri Chatterjee; Bose, Sankhadip; Das, Gitishree; Shin, Han-Seung; Patra, Jayanta Kumar
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SENET-AOP: A Computational Framework Model for Prioritizing Antioxidant Protein Targets in Drug Discovery
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IF5.9
delete2026-05-09
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deleteShaobin Chen; Yuhan Zhu; Jinrun Liu; Yezi Liu; Sisi He; Xiaolei Zhu
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Corrigendum to ‘Synthesis and structure-activity relationships of N - (3 - (1H-imidazol-2-yl) phenyl) - 3-phenylpropionamide derivatives as a novel class of covalent inhibitors of p97/VCP ATPase’ [ Eur. J. Med. Chem. 248 (2023) 115094]
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IF5.9
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deleteKe Wang; Lianguo Chen; Xinyan Dai; Zi Ye; Chuan Zhou; Chong-Jing Zhang; Zhiqiang Feng
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Novel hybrid 1,4-naphthoquinone-endoperoxide antimalarial hits: synthesis, stereoisomeric separation, and biological evaluation
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-09
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deleteAlexandre Benech; Sébastien Hutter; Nicolas Vanthuyne; Omar Khoumeri; Christophe Curti; Patrice Vanelle; Thierry Terme; Nadine Azas
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Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-09
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deleteIsabel J. Lee; Qi Li; Tushar Raskar; Jenna Pellegrino; Andrew K. Ecker; Sara Y. Howard; James S. Fraser; Ian B. Seiple
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Structural Optimization of Cholesteryl ester transfer protein inhibitors: From Early Scaffolds to Advanced Clinical Candidates
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-08
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deleteMahla Abdollahzadeh; Mahin Ramezani; Mahdi Hatamipour
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Current Applications and Development of Dual-Target Inhibitors of IDO1/TDO: From Tumor Immunology to Neuropsychiatric Disorders
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IF5.9
delete2026-05-08
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deleteWei Guo; Jing-Zheng Zhang; Lu-Yuan Cui; Kai-Ming Wang; Juan Zhang; Cheng-Shi Jiang
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Design, synthesis and anti-necroptosis evaluation of RIPK1 inhibitors derived from sunitinib
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-07
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deleteYuhan Jiang; Yiwei Zheng; Meiting Zou; Long Zheng; Zhongwen Luo; Lingyi Kong; Xiaobing Wang
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Exploring Diverse Chemotypes of Natural Polyenes as Promising Antimicrobial Candidates: Latest Progress and Limitations
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-06
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deleteGautam Kumar; Murali Manohar Pandey
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Design of fibroblast growth factor receptor (FGFR) inhibitors containing a 3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one motif
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-06
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deleteYuanli Yang; Ziwei Wang; Yu Zhang; Juan Xu; Yuanyuan Li; Huaxiang Fang; Huan He; Silong Zhang
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Design, synthesis and structure-activity relationship study of novel indole-pyrrole scaffold compounds targeting Nur77 in colorectal tumor cells
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-05
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deleteQi Zhao; Jingmei Liang; Jin Zhou; Meifeng Zeng; Wenbiao Zhang; Yuan Cao; Xiaokun Zhang; Xiaohui Chen; Guobin Xie; Ying Su; Zhiping Zeng
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Design, synthesis, and evaluation of indole-pyridine chalcone derivatives as novel HK2 inhibitors to modulate macrophage glycolysis and inflammation for IBD treatment
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IF5.9
delete2026-05-05
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deleteYawei Han; Guangyuan Liu; Huimin Yuan; Yuhao Wei; Mingze Wu; Sijie Yin; Yunlong Liu; Liqun Gu; Jindong Zhang; Xiaoshuang Wang; Yirong Zhou; Ming Xiang; Mengzhu Zheng
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Discovery and Characterization of YSA64, a RBM39 Degrader with In Vivo Efficacy and Potent Cellular Activity in Pediatric Ewing Sarcoma A673
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-02
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deleteXilin Lyu; Zhiyi Wang; Yanyan Shen; Xiancheng Wang; Yixuan Wang; Shumeng Yu; Biyu Yang; Ziqin Yan; Shijie Zhang; Yuhang Lu; He Huang; Yi Chen; Yujun Zhao
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In silico studies, synthesis, and biological evaluation of novel imidazopyridine-based CYP4Z1 inhibitors targeting breast cancer stem cells
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-01
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deleteLu, Yu; Chen, Kailin; Wang, Hongqi; Zhang, Chi; Huang, Xinting; Wang, Zihan; Chen, Haitao; Niu, Miaomiao; Yao, Hong; Zheng, Lufeng; Xu, Shengtao; Guo, Qianqian
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Design, synthesis and biological evaluation of selective inhibitors against the L858R/T790M/C797S mutant EGFR kinase based on the scaffold of brigatinib
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-05-01
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deleteShi Ding; Haotian Ding; Zhenzhen Zhan; Jinpeng Wang; Xinru Song; Yuanyu Wu; Xin Wang; Hanxue Zheng; Zhongyu Tang; Xiaoqing Peng; Shaoting Wu; Ju Liu; Jiwei Shen; Ye Chen
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An integrated machine learning and computational framework with experimental validation for the identification of novel CXCR4 inhibitors
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-04-30
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deleteMushtaq Ahmad Wani; Pooja Kumari; Faisal Irshad; Yashi Gupta; Monika Gupta; Anindya Goswami; Zabeer Ahmed; Amit Nargotra
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Discovery and Optimization of Novel TEAD Inhibitors for In Vivo Investigation Against Hepatocellular Carcinoma
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-04-30
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deleteDounan Xu; Wenxi Su; Yuhui Miao; Xiaolin Luo; Yipan Luo; Shuang Hu; Yongpeng Wang; Chujiao Hu; Cheng Luo; Guangming Li; Yuanyuan Zhang; Shijie Chen; Huan Xiong
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Novobiocin Defines an Asn28 Allosteric Pocket that Governs SARS-CoV-2 Main Protease Activity
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-04-30
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deleteMohit Bhardwaj; Raushan Anjum; Sheetal Thakur; Pradeep Sharma; Ashok Kumar Patel
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Discovery of Preclinical Candidate CG-0988, a Novel Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease Inhibitor Bearing Spirooxindole
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-04-30
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deleteXiubo Tang; Kai Hou; Xiaowu Chen; Wenyuan Fan; Hao Wu; Jia Meng; Changliang Lu; Gong-Xin He
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