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European Journal of Medicinal Chemistry cover

European Journal of Medicinal Chemistry

IF5.9
Papers16730
Citations59745
Journal Papers 16647
Publication Date
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Novel enantiopure pyridine-based aminoalcohols as promising antimalarial candidates
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-24
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deleteOAAI
deleteAurélie Herrero; Camille Tisnerat; Guillaume Bentzinger; Etienne Pair; Anne Bouchut; Romain Mustière; Christophe Landry; Fabien Gosselet; Catherine Mullié; Patrice Agnamey; Nicolas Taudon; Bruno Pradines; Alexandra Dassonville-Klimpt; Pascal Sonnet
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Recent advances in the medicinal chemistry of HSV-1 inhibitors (2020–2025): Emerging targets, modalities, and translational challenges
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-23
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PREAI
deleteQiaomei Zhou; Baohu Li; Yehong Dai; Chunhua Ma; Shenghua Gao; Peng Zhan; Jinfei Yang
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Icaritin and its N-Boc-amino acid ester derivatives: Chemistry, structure-activity relationships, and preliminary mechanistic insights
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-22
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PREAI
deleteGuohua Ma; Yuan Gao; Kaiyue Zhang; Hongyu Zhao; Wenyan Gao; Yufang He; Yuwei Zhao; Minlun Nan
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Exploring MV14 as a nitric oxide-releasing strategy for bladder cancer: From synthesis to in vivo evaluation
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-22
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PREAI
deleteMiriam López; María Varela; Mariana Ingold; María Laura Lavaggi; Martín Breijo; Florencia Fontes; Marcelo Fernández; José Manuel Verdes; Juan Manuel Ramirez-Reyes; Victoria Yozzi; Camila Romero; Rosina Dapueto; Ana Laura Reyes; Manuela Bentura; Eduardo Savio; Paula Céspedes; Karen Perelmuter; Mariela Bollati-Fogolín; Gloria V. López; Paola Hernández
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deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-21
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PREAI
deleteKavita Dhariyal
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Small-molecule photosensitizer for enhanced antiangiogenesis and immunosuppressive tumor microenvironment reprogramming in anti-metastatic photodynamic therapy
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-21
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PREAI
deleteSijia Yu; Lirui Tang; Yixuan Liu; Meiqi Yan; Juanjuan Chen; Jinluan Li
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Investigating the anti-TNBC potential of new quinazoline-based PAK4 inhibitors: design, synthesis and biological evaluation
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-21
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PREAI
deleteShuang Hao; Yi-fan Niu; Meng-chen Si; Wei-xin Zheng; Chen-guang Zhao; Xin Li; Rui Wang; Jing-han Yan; Zheng-hao Cai; Shuang Cai; Jia-yin Yue; Ting-jian Zhang; Fan-hao Meng
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AVP-GPT2: Prompt-conditioned fine-tuning of a GPT-2 protein language model for antiviral peptide identification
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-21
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PREAI
deletenull Maryam; Hamza Zahid; Kil To Chong; Hilal Tayara
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Substituted methyl acridone-carboxylate derivatives as CD1/CD2 dual-targeting HDAC6 inhibitors to ameliorate the pathological phenotype of Alzheimer's disease
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-19
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PREAI
deleteJianan Ye; Sijia Yin; Yutao Lin; Shuhui Yang; Lieen Ma; Yang Wang; Kangyang Gao; Yule Wang; Xinhang Yang; Zhichao Yang; Ning Wang; Hao Liu; Shujun Xu; Wei Cui; Bin Zhang
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Targeting Amino Acid Biosynthesis Pathways for Antibacterial Drug Discovery: Chemical Lessons and Design Opportunities
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-19
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deleteAhmed E. Ibrahim; Amatus Salam; Naiem A. Wani; Musarrat Salim; Esraa Y. Ahmad; Shabir Hassan; Emilia Oueis
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In silico-guided design, synthesis and in vitro evaluation of thiazolo-pyridines targeting SARS-CoV-2 Nsp13
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-19
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deleteRoberta Bivacqua; Roberta Emmolo; Gianmarco Gualtieri; Simona Di Martino; Marilia Barreca; Virginia Spanò; Maria Valeria Raimondi; Angela Corona; Francesco Ortuso; Enzo Tramontano; Isabella Romeo; Alessandra Montalbano; Paola Barraja; Stefano Alcaro
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Cyclometalated Iridium Complex with Red-Light Activation for Dual Ferroptosis-Apoptosis Cancer Therapy
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-18
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deleteChuansheng Xu; Xinda Yang; Jian Meng; Yan Gao; Chunhui Wang; Erli Zhang; Shuo Shi
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Harnessing Chirality for Enhanced Stability: An all-D Protease Resistant Antimicrobial Peptide Active Against Drug-Resistant Skin Bacteria
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-18
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deleteAnna Dziuba; Raffaella Ausiello; Annarita Del Gatto; Sanyukta Darnal; Emilia Maria Pedone; John Kerr White; Eugenio Notomista; Natalia Ferraz; Patrizia Contursi; Valeria Cafaro; Annelie Brauner
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Discovery of H-10 as a potent and safe GABAA receptor positive allosteric modulator: A novel benzothiazine-triazole lead compound with broad-spectrum anticonvulsant activity
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-18
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deleteDi Hu; Ying Wang; Jinling Yu; Xuesong Yan; Xiu Cheng; Yeshan Zhu; Yun Hong; Xinhua Liu; Yixuan Zhang; Hao Liu; Dachuan Liu
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deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-17
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deleteSri Mounika Bellapukonda; null Akanksha; Mainak Ghosh; Rani Bandela; Pardeep Kumar; Ramakrishna Kodi; Subhendu Ghosh; Laxma Naik Korra; Nitin Pal Kalia; Srinivas Nanduri; Venkata Madhavi Yaddanapudi
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Discovery of a novel natural USP25 inhibitor via an integrated deep learning-guided screening strategy with molecular dynamics validation
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-17
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PREAI
deleteZhonghua Li; Zhenzhen Wang; Zhenzhen Liu
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Novel 1-benzyl-oxindole Indole Hybrids Targeting PDGFR-β, SRC, and c-MET Signaling and Inducing Caspase-3-Dependent Apoptosis in Pancreatic Cancer Cells
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-17
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deleteTuğçe Cinek; Merve Yildirim; Gökçe Cihan-Üstündağ; Oykum Genc Akar; Serap Sancar; Ayse Erol-Bozkurt; Güneş Özen-Eroğlu; Begum Kucuker; Fusun Oztay; Serap Kuruca; Sehnaz Bolkent; Nilgün Karalı
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Preclinical Evaluation of MC1R Targeted Radiopharmaceuticals Using The 203/212Pb Theranostic Pair
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-17
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deleteJarred Michael Scaffidi-Muta; Didier Boucher; Kwong Ching Li; Feifei Liu; William Tieu; Andrew David Abell
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Novel far-red fluorescent theranostic probes for selective imaging and targeted therapy of BET proteins in breast cancer
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-16
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deleteYuqi Gao; Wenjie Liu; Xuerui Zhang; Leyan Qin; Shujun Liu; Xuesong Liu; Gaopan Dong; Bo Liu; Xu Wang; Shubin Song; Tingting Liu
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Targeted Probes for Fluorescence Imaging and Photodynamic Therapy of Breast Cancer
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-09-16
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deleteHans Schmitthenner; Zihao Li; Tori L. Russell; Jaclyn Conley; Gabriella Redman; Christopher W. DeNyse; Andrew M. O’Brien; Micah J. Hrubec; Matthew P. Henry; Griffin Pileski; Ernestina Domey; Anakin de la Cruz Flecha; Lute Douglas; Hyla Sweet; Regine Choe; Kamaljit Kaur; Maureen C. Ferran; Timothy M. Baran
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