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Mannose-glycosylated BSA and metal-phenolic network nanocoatings enhance gastrointestinal transit survival and intestinal adhesion of Lactobacillus plantarum B2
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DOI：10.1016/j.crfs.2026.101501.png)
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Abstract
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• GBSA prepared in choline chloride/mannose NADES enhanced intestinal targeting via mannose receptors. • GBSA/MPN layer-by-layer nanocoating enabled effective oral delivery of L. plantarum B2. • Coated L. plantarum B2 exhibited enhanced tolerance to gastrointestinal fluids and ROS. • GBSA nanocoating improved L. plantarum B2 intestinal adhesion and colonization efficiency. • Nano-encapsulation preserved L. plantarum B2 viability and riboflavin production capacity.
Keywords:
Glycosylated bovine serum albumin
Intestinal adhesion
Metal-phenolic networks
Probiotic encapsulation
Lactobacillus plantarum B2
Riboflavin
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