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Persistence of large P. aeruginosa aggregates despite reduced airway burden in people with cystic fibrosis on CFTR modulator therapy

delete2026-06-28
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PRE
AI
A
Amanda J. Morris
S
Shafinaz Eisha
Y
Yvonne Yau
S
Sara Goel
M
Michelle Shaw
W
William H. DePas
I
Isaac Martin
A
Arunan Selvarajah
M
Mellissa Gaudet
E
Elizabeth Tullis
D
Dao Nguyen
V
Valerie J. Waters *
DOI:10.1016/j.jcf.2026.06.012delete
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Abstract

Abstract

En 中文
• CFTR modulator therapy reduced P. aeruginosa biovolume and aggregate number. • Maximum aggregate size was comparable between those on modulators and those not. • 20% of P. aeruginosa persisted as large aggregates in pwCF on CFTR modulators.

Journal

Journal of Cystic Fibrosis cover
Journal of Cystic Fibrosis
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6
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2.9K
Citations:
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