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Protein matchmaking through representation learning

delete2021-10-01
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OA
AI
M
Michael Heinzinger
C
Christian Dallago *
B
Burkhard Rost
DOI:10.1016/j.cels.2021.09.007delete
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Abstract

Abstract

En 中文
Sledzieski, Singh, Cowen, and Berger employ representation learning to predict protein interactions and associations, additionally identifying binding residues between protein pairs. Generalizability is showcased by training on one organism while evaluating on others. The work exemplifies how transfer of AI-learned representations can advance knowledge in molecular biology.

Journal

Cell Systems cover
Cell Systems
IF:
7.7
Papers:
1.4K
Citations:
1.0W

Organization

T
Technical University of Munich
Scholars:
5.2W
Papers: 3.9W
Citations: 6.2W