Response surface methodology-guided design of oil-in-water emulsions coated with complex coacervates for precision intestinal delivery of sulforaphane

2026-08-08

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Su Min Park

Jong Hyeon Han

Keun Woo Kang

Hyun Ju Lee

Hyeonjin Kim

Sung Gu Han *

DOI：10.1016/j.foodchem.2026.150714

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• Sulforaphane (SFN)-loaded O/W emulsion was stabilized by complex coacervation. • Optimized SFN-ECC showed compact core-shell structure and high stability. • SFN-ECC had low SFN release in gastric, high in intestinal condition. • O/W emulsion-complex coacervation is useful for bioavailability enhance of SFN in foods.

Keywords:

Sulforaphane

Emulsion

Complex coacervation

Encapsulation

Response surface methodology

Response surface methodology-guided design of oil-in-water emulsions coated with complex coacervates for precision intestinal delivery of sulforaphane

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