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Sequence-dependent RNA cleavage by the 8–17 DNAzyme: Identification of preferred tetranucleotide motifs

delete2025-12-14
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PRE
AI
S
Satoko Nakajima
S
S. Miyakawa
S
Shu Ohno
H
Haruki Ikemoto
R
Rikuto Maruyama
K
Kosuke Chiba
R
Ryota Suginaka
C
Chihiro Oda
Y
Yuuya Kasahara
K
Kaori Fukuzawa *
S
Satoshi Obika
T
Takao Yamaguchi *
DOI：10.1016/j.bmc.2025.118520delete
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Abstract

Abstract

En 中文
• Sequence-dependent RNA cleavage was identified for the 8–17 DNAzyme. • Specific tetranucleotide motifs are preferentially cleaved by the 8–17 DNAzyme. • Computational analyses revealed structural basis underlying this sequence preference.

Journal

B
Bioorganic and Medicinal Chemistry
IF:
3
Papers:
1.7W
Citations:
2.7W

Organization

T
the university of osaka
Scholars:
2.8W
Papers: 1.8W
Citations: 6
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