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Bioorganic and Medicinal Chemistry

IF3
Papers16741
Citations27329
Journal Papers 16773
Publication Date
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Discovery and characterization of a high-affinity G-quadruplex binding peptide via mRNA display
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-27
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PREAI
deleteNaka Kudo Ida; Yoshimasa Kawaguchi; Shiroh Futaki; Miki Imanishi
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Luminescent dihydroquinolines: fluorescence in aqueous media and insights into anticancer activity
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-18
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PREAI
deleteLidiane Gomes de Araújo; Rafael Gomes Soares; Bruno Galdino Lopes; Ana Rita de Sousa França; Karen Isabelly Santos Cardoso Brandão; Edilson Beserra de Alencar Filho; Yuri Virgílio dos Santos; Gardenia Carmen Gadelha Militão; Claudio Gabriel Lima-Junior; Rodrigo Cristiano
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New pyrazolo[1,5-a]pyrimidine derivatives as potential CDK2 inhibitors and apoptosis-driven antiproliferative agents
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-18
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PREAI
deleteAhmed Abd El-Hamed El-Rahmany; Nadia A. Khalil; Mohamed S. Nafie; Wagdy M. Eldehna; Hatem A. Abdel-Aziz; Marwa S.A. Hassan
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Discovery and optimization of novel and potent allosteric HIV-1 integrase inhibitors with a spiro[indene] moiety
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-18
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PREAI
deleteKaoru Adachi; Tomoyuki Manabe; Takayuki Yamasaki; Akira Suma; Yosuke Ogoshi; Akihiko Takahashi; Takuya Orita; Akihiro Nomura; Tsuyoshi Adachi; Yoshitsugu Ohata; Yoshiyuki Akiyama; Susumu Miyazaki
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Design, synthesis, and biological evaluation of 2-amino-1,3,4-thiadiazoles as new potential EGFR inhibitors for treatment of cancer
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-18
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PREAI
deleteSachin M. Thorat; Summon Koul; Sachin Kote; Ramakrishna G. Bhat
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Novel PROTACs with polyhedral alkanes as linkers for enhanced ALK degradation in drug-resistant NSCLC
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-16
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PREAI
deleteDongchen Chu; Huijie Han; Chaochun Wei; Xiaokun Zhang; Hong Yan; Juan Wang
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Sequence-dependent RNA cleavage by the 8–17 DNAzyme: Identification of preferred tetranucleotide motifs
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-14
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PREAI
deleteSatoko Nakajima; Shuhei Miyakawa; Shu Ohno; Haruki Ikemoto; Rikuto Maruyama; Kosuke Chiba; Ryota Suginaka; Chihiro Oda; Yuuya Kasahara; Kaori Fukuzawa; Satoshi Obika; Takao Yamaguchi
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Synthesis and biological evaluation of novel C1 or C3 amino derivatives of A-ring 1,2,3-trisubstituted 19-nor-vitamin D3
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-14
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deleteTania González-García; Lieve Verlinden; Stefanie Doms; Annemieke Verstuyf; Susana Fernández; Miguel Ferrero
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The development of anti-HIV agents targeting APOBEC3G/Vif axis
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-11
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PREAI
deleteQiqi Bao; Jiajia Wen; Fengjiao Xiang; Ling Ma; Jiwei Ding; Xinlu Wang; Shan Cen; Jinming Zhou
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Corrigendum to “Redox-cleavable disulfide linker enhances siRNA delivery by prodrug-type bifunctional cell-penetrating peptide” [Bioorg. Med. Chem. 130 (2025) 118383]
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-10
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deleteKeita Wakamori; Yuzuki Hashikawa; Hidehito Urata; Shun-ichi Wada
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Design, synthesis, and biological evaluation of quinazoline–benzohydrazide and quinazoline–benzothiazole hybrids uncovering a dual EGFR/VEGFR-2 inhibitor with pronounced cytotoxic activity against triple-negative breast Cancer
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-06
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PREAI
deleteNoura F.M. El Hamaky; Abdelrahman Hamdi; Waleed A. Bayoumi; Abdullah A. Elgazar; Magda N.A. Nasr
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Design, synthesis and anti-tumor activities of pyridine-benzamide containing dithiocarbamate moiety as EZH2 inhibitors
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-05
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PREAI
deleteHui Lu; Yuling Xiang; Ping Gong
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Broad-spectrum anti-influenza activity of the NMPA-approved drug Pamiparib is uncovered by virtual docking to the evolutionarily conserved domain of IAV-M2 protein
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-05
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PREAI
deleteMin Chen; Huifang Jiao; Dandan Lu; Wenhuan Chen; Zhen Yang; Xue Liang; Pengcheng Wei; Kunpeng Liu
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Biomimetic semi-synthesis, structural optimization and anti-HIV activity of naturally scarce Eupholathone-, Lathyranone- and Integerrimine-type Euphorbia Diterpenoids
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-05
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PREAI
deleteWei Cheng; Peng Wen; Pei-Yin Song; Yang Zhang; Jin-Bu Xu; Steven De Jonghe; Dominique Schols; Feng Gao
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Design, synthesis, and biological evaluation of a focused pyrrolo- and pyrido-quinazolinone natural products-templated library for anti-fungal and anthelmintic activities
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-05
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PREAI
deleteRomina E. D'Almeida; Paulina Chen; Yanchang Huang; Emily Goetz; Vamshikrishna Reddy Sammeta; Bo Yang; Reeta Rao; Sivappa Rasapalli; Mostafa Elfawal
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Linkers for effective peptide-drug conjugates
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-02
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PREAI
deleteMohamad Fajar; Rani Maharani; Unang Supratman
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Novel indole-based indoleamine 2,3-dioxygenase-1 (IDO1) inhibitors: design, synthesis, and antidepressant evaluation
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-12-02
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PREAI
deleteJuan Zhang; Wen-Jing Gao; Yu-Xi Zheng; Jia-Dong Shao; Nai-Yu Zhang; Wei Guo; Shuai Wang; Qing Zhao; Kongkai Zhu; Ming Gao; Jin-Hai Yu; Ning Meng; Cheng-Shi Jiang
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Discovery of thiosemicarbazone derivatives as promising SARS-CoV-2 Mpro inhibitors by spectroscopy and microscale thermophoresis
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-11-29
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PREAI
deleteXing Xue; Leyao Chen; Miao Zhang; Xiaoyu Chang; Ruiyong Wang
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Recent developments in synthesis and antimalarial activities of chalcone hybrids
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-11-29
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PREAI
deleteLekkala Ravindar; Lekkala Revathi; Cheong Fei Wen; Nurul Izzaty Hassan; Yee Ling Lau
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Discovery of novel hybrids of coumarin and quinoline as potential anti-Alzheimer's disease agent
deleteBioorganic & Medicinal Chemistry
IF3
delete2025-11-26
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PREAI
deleteShun Li; Xinrui Li; Shuanglong Li; Daoyuan Chen; Chunli Xia
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