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SMAS: Structural MRI-based AD Score using Bayesian supervised VAE
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DOI：10.1016/j.compbiomed.2025.110829.png)
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Abstract
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• Structural MRI-based AD Score (SMAS) quantifies AD-specific morphometric patterns. • SMAS enables stratification and monitoring of individuals along the AD continuum. • SMAS outperforms both SPARE-AD and hippocampal volume across ADNI and DELCODE. • SMAS yields interpretable maps depicting regional contributions to the prediction.
Keywords:
Brain morphology indices
Bayesian Supervised Variational Autoencoder
Cognitive decline
Alzheimer’s disease
Bayesian inference
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