.png){kind=icon}
Return
Spatiotemporal Isolation Based Super-Resolution Microscopy
.png){kind=icon}
PRE
AI
DOI：10.1002/cjoc.202200764.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Super-resolution microscopy (SRM) is a powerful imaging technique that overcomes the diffraction limit and allows imaging of the object structure in the nanoscale. However, SRM suffers from a tradeoff between spatial and temporal resolution, which prevents further exploration in scientific discoveries. In this review, we mainly focus on the development of improving spatiotemporal resolution of SRM, including 1) SRM based on physical and computational principles, 2) physical and computational factors affecting SRM, from which we conclude some strategies for developing new types of SRM, 3) the summary of the various types of SRM based on physical and computational principles, as well as, the analysis of the ordinary and developing SRM. Both SRMs based on physical principles and computational principles can be realized with spatial isolation and temporal isolation methods. We expect this review will offer some new ideas to improve the spatial and temporal resolution simultaneously, which may lead to more new discoveries in biology, chemistry, and materials science.
Keywords:
Super-resolution imaging
Fluorescence
Luminescence
Spatial isolation
Temporal isolation
Journal
IF:
5.5
Papers:
8.6K
Citations:
1.1W
Organization
Cited Papers
ShareSaveShareSaveSingle-molecule fluorescence microscopy review: shedding new light on old problems.png)
BIOSCIENCE REPORTS
OAAI
BIOSCIENCE REPORTSIF4.7
OAAIShareSaveA spontaneously blinking fluorophore based on intramolecular spirocyclization for live-cell super-resolution imagingNATURE CHEMISTRY
NATURE CHEMISTRYIF20.2
PREAI
ShareSaveSub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)NATURE METHODSOAAI
NATURE METHODSIF32.1
OAAIShareSave
View more