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Structural insights into IMP2 dimerization and RNA binding
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DOI：10.1016/j.jsb.2025.108247.png)
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Abstract
En 中文
• Full-length IMP2 forms oligomers but predominantly adopts a dimeric conformation. • The oligomeric states of IMP2 are sensitive to ionic strength. • IMP2 dimer adopts head-to-tail orientation of the two IMP molecules upon RNA binding.
Keywords:
IGF2BP2
IMP2
RNA binding protein (RBP)
SAXS
HDX-MS
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