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The Reactome pathway knowledgebase

delete2013-11-15
delete3.5K
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OA
AI
D
David Croft
A
Antonio Fabregat
R
Robin Haw
M
M Orlic-Milacic
W
Weiser, Joel
G
Guanming Wu
C
Caudy, Michael
P
Phani Garapati
M
Marc Gillespie
M
Maulik R. Kamdar
B
Bijay Jassal
S
S Jupe
L
Lisa Matthews
B
Bruce May
P
Palatnik, Stanislav
K
Karen Rothfels
V
Veronica Shamovsky
S
Song, Heeyeon
M
Mark Williams
E
Ewan Birney
H
Henning Hermjakob
L
Lincoln Stein
P
Peter D’Eustachio *
DOI:10.1093/nar/gkt1102delete
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Abstract

Abstract

En 中文
Reactome (http://www.reactome.org) is a manually curated open-source open-data resource of human pathways and reactions. The current version 46 describes 7088 human proteins (34% of the predicted human proteome), participating in 6744 reactions based on data extracted from 15 107 research publications with PubMed links. The Reactome Web site and analysis tool set have been completely redesigned to increase speed, flexibility and user friendliness. The data model has been extended to support annotation of disease processes due to infectious agents and to mutation.
Keywords:
COMMUNITY STANDARD
ONTOLOGY
DATABASE
REPRESENTATION
INTEGRATION
NETWORK
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Journal

Nucleic Acids Research cover
Nucleic Acids Research
IF:
13.1
Papers:
3.6W
Citations:
29.0W

Organization

E
european molecular biology laboratory (embl)
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8.3K
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Citations: 31
O
Ontario Institute for Cancer Research
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U
university of toronto
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