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Three dimensional bioelectronic interfaces to small-scale
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DOI：10.1016/j.copbio.2021.07.023.png)
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Abstract
En 中文
Recent advances in bio-interface technologies establish a rich range of electronic, optoelectronic, thermal, and chemical options for probing and modulating the behaviors of smallscale three dimensional (3D) biological constructs (e.g. organoids, spheroids, and assembloids). These approaches represent qualitative advances over traditional alternatives due to their ability to extend broadly into volumetric spaces and/or to wrap tightly curved surfaces of natural or artificial tissues. Thin deformable sheets, filamentary penetrating pins, open mesh structures and 3D interconnected networks represent some of the most effective design strategies in this emerging field of bioelectronics. This review focuses on recent developments, with an emphasis on multimodal interfaces in the form of tissue-embedding scaffolds and tissue-surrounding frameworks.
Keywords:
FIELD-EFFECT TRANSISTORS
3D MESOSTRUCTURES
ORGANOIDS
SILICON
ARCHITECTURES
SCAFFOLDS
GROWTH
CELLS
MODEL
ARRAY
Journal
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7
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Citations:
1.9W