Vemurafenib

doi:10.1038/nrd3579

Return

Vemurafenib

2011-10-31

142

PRE

DOI：10.1038/nrd3579

Original request for help

Save

Abstract

Keywords:

MELANOMA

BRAF

INHIBITION

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Nature Reviews Drug Discovery

IF:

101.8

Papers:

5.1K

Citations:

5.3W

Organization

Massachusetts General Hospital

Scholars:

3.4W

Papers: 2.6W

Citations: 8.6W

Harvard University

Scholars:

26.5W

Papers: 22.0W

Citations: 28.7W

Cited Papers

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2010-08-26

3.2K

OAAI

Flaherty, Keith T.; Puzanov, Igor; Kim, Kevin B.; Ribas, Antoni; McArthur, Grant A.; Sosman, Jeffrey A.; O'Dwyer, Peter J.; Lee, Richard J.; Grippo, Joseph F.; Nolop, Keith; Chapman, Paul B.

Save

Correlation between prenatal ultrasound and fetal autopsy findings in fetal anomalies terminated in the second trimester

Prenatal Diagnosis

IF0

2007-03-05

PREAI

Hulya Akgun; Mustafa Basbug; Mahmut Tuncay Ozgun; Ozlem Canoz; Fatma Tokat; Nurcan Murat; Figen Ozturk

Save

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2010-08-19

1.3W

OAAI

Hodi, F. Stephen; O'Day, Steven J.; McDermott, David F.; Weber, Robert W.; Sosman, Jeffrey A.; Haanen, John B.; Gonzalez, Rene; Robert, Caroline; Schadendorf, Dirk; Hassel, Jessica C.; Akerley, Wallace; van den Eertwegh, Alfons J. M.; Lutzky, Jose; Lorigan, Paul; Vaubel, Julia M.; Linette, Gerald P.; Hogg, David; Ottensmeier, Christian H.; Lebbe, Celeste; Peschel, Christian; Quirt, Ian; Clark, Joseph I.; Wolchok, Jedd D.; Weber, Jeffrey S.; Tian, Jason; Yellin, Michael J.; Nichol, Geoffrey M.; Hoos, Axel; Urba, Walter J.

Save

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2011-06-30

6.7K

OAAI

Chapman, Paul B.; Hauschild, Axel; Robert, Caroline; Haanen, John B.; Ascierto, Paolo; Larkin, James; Dummer, Reinhard; Garbe, Claus; Testori, Alessandro; Maio, Michele; Hogg, David; Lorigan, Paul; Lebbe, Celeste; Jouary, Thomas; Schadendorf, Dirk; Ribas, Antoni; O'Day, Steven J.; Sosman, Jeffrey A.; Kirkwood, John M.; Eggermont, Alexander M. M.; Dreno, Brigitte; Nolop, Keith; Li, Jiang; Nelson, Betty; Hou, Jeannie; Lee, Richard J.; Flaherty, Keith T.; McArthur, Grant A.

Save

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2008-02-26

1.3K

OAAI

Tsai, James; Lee, John T.; Wang, Weiru; Zhang, Jiazhong; Cho, Hanna; Mamo, Shumeye; Bremer, Ryan; Gillette, Sam; Kong, Jun; Haass, Nikolas K.; Sproesser, Katrin; Li, Ling; Smalley, Keiran S. M.; Fong, Daniel; Zhu, Yong-Liang; Marimuthu, Adhirai; Nguyen, Hoa; Lam, Billy; Liu, Jennifer; Cheung, Ivana; Rice, Julie; Suzuki, Yoshihisa; Luu, Catherine; Settachatgul, Calvin; Shellooe, Rafe; Cantwell, John; Kim, Sung-Hou; Schlessinger, Joseph; Zhang, Kam Y. J.; West, Brian L.; Powell, Ben; Habets, Gaston; Zhang, Chao; Ibrahim, Prabha N.; Hirth, Peter; Artis, Dean R.; Herlyn, Meenhard; Bollag, Gideon

Save

Initial Effects of the Left Ventricular Repair by Plication May Not Last Long in a Rat Ischemic Cardiomyopathy Model

Circulation

IF0

2001-09-18

PREAI

Takeshi Nishina; Kazunobu Nishimura; Sadatoshi Yuasa; Senri Miwa; Takuya Nomoto; Yutaka Sakakibara; Nobuhiro Handa; Ichiro Hamanaka; Yoshihiko Saito; Masashi Komeda

Save

Selective BRAFV600E Inhibition Enhances T-Cell Recognition of Melanoma without Affecting Lymphocyte Function

CANCER RESEARCH

IF16.6

2010-06-30

653

OAAI

Boni, Andrea; Cogdill, Alexandria P.; Dang, Ping; Udayakumar, Durga; Njauw, Ching-Ni Jenny; Sloss, Callum M.; Ferrone, Cristina R.; Flaherty, Keith T.; Lawrence, Donald P.; Fisher, David E.; Tsao, Hensin; Wargo, Jennifer A.

Save

no more