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What cannot be seen correctly in 2D visualizations of single-cell 'omics data?

delete2023-09-01
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OA
AI
S
Shu Wang
E
Eduardo D. Sontag *
D
Douglas A. Lauffenburger *
DOI:10.1016/j.cels.2023.07.002delete
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Abstract

Abstract

En 中文
A common strategy for exploring single-cell 'omics data is visualizing 2D nonlinear projections that aim to preserve high-dimensional data properties such as neighborhoods. Alternatively, mathematical theory and other computational tools can directly describe data geometry, while also showing that neighborhoods and other properties cannot be well-preserved in any 2D projection.
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Journal

Cell Systems cover
Cell Systems
IF:
7.7
Papers:
1.4K
Citations:
1.0W

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Northeastern University
Scholars:
2.4W
Papers: 1.5W
Citations: 3.0W