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D

Douglas A. Lauffenburger

department of biological engineering

126H-index
1.1KPaper Count
6.1WCitation Count
Published Papers 348
Publication Date
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Maternal influenza vaccination boosts durable breast milk antibody-mediated protection in infants
errnpj Vaccines
IF6.5
err2026-07-31
err0
errOAAI
errRemziye E. Wessel; Xin Tong; Allison Bhattacharya; Allison R. Burrell; Sara Spranger; Ardythe L. Morrow; Daniel C. Payne; Margaret E. Ackerman; Galit Alter; Mary A. Staat; Douglas A. Lauffenburger
errShare
errSave
Protein networks are influenced by maternal BMI and differentiate preterm birth types
errCommunications Medicine
IF6.3
err2026-02-12
err0
errOAAI
errPaola A. Lopez Zapana; Chelsea A. DeBolt; Luka Karginov; Valerie Riis; Liqhwa Ncube; Andrea G. Edlow; Michal A. Elovitz; Douglas A. Lauffenburger
errShare
errSave
Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes
errJCI Insight
IF6.1
err2025-12-22
err0
errOAAI
errBridges, Kate; Awany, Denis; Gela, Anele; Mwambene, Temwa-Dango; Kurtz, Sherry L.; Baker, Richard E.; Elkins, Karen L.; Sassetti, Christopher M.; Scriba, Thomas J.; Lauffenburger, Douglas A.
errShare
errSave
Maternal proteome profiling reveals dynamic gestational age-specific responses to de novo vaccination
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-12-01
err0
PREAI
errLopez Zapana, Paola A.; Shook, Lydia L.; Joughin, Brian A.; Jasset, Olyvia J.; Liu, Zhaojing A.; Yinger, Rachel, V; Acharya, Kalpana D.; Gray, Kathryn J.; Elovitz, Michal A.; Lauffenburger, Douglas A.; Edlow, Andrea G.
errShare
errSave
Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2025-02-15
err0
errOAAI
errPullen, Krista M.; Finethy, Ryan; Ko, Seung-Hyun B.; Reames, Charlotte J.; Sassetti, Christopher M.; Lauffenburger, Douglas A.
errShare
errSave
Combinatorial Fc modifications for complementary antibody functionality
errMABS
IF7.3
err2025-02-14
err0
errOAAI
errYannic C. Bartsch; Nicholas E. Webb; Eleanor Burgess; Jaewon Kang; Douglas A. Lauffenburger; Boris D. Julg
errShare
errSave
Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2025-02-11
err0
errOAAI
errGordon, Khloe S.; Perez, Caleb R.; Garmilla, Andrea; Lam, Maxine S. Y.; Aw, Joey J. Y.; Datta, Anisha; Lauffenburger, Douglas A.; Pavesi, Andrea; Birnbaum, Michael E.
errShare
errSave
A practical guide to FAIR data management in the age of multi-OMICS and AI
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-01-20
err0
errOAAI
errMugahid, Douaa; Lyon, Jared; Demurjian, Charlie; Eolin, Nathan; Whittaker, Charlie; Godek, Mark; Lauffenburger, Douglas; Fortune, Sarah; Levine, Stuart
errShare
errSave
AutoTransOP: translating omics signatures without orthologue requirements using deep learning (vol 10, 13, 2024)
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2024-12-13
err0
errOAAI
errMeimetis, Nikolaos; Pullen, Krista M.; Zhu, Daniel Y.; Nilsson, Avlant; Hoang, Trong Nghia; Magliacane, Sara; Lauffenburger, Douglas A.
errShare
errSave
SARS-CoV-2 infection prior to vaccination amplifies Fc-mediated humoral profiles in an age-dependent manner
errCELL REPORTS
IF6.9
err2024-09-01
err0
errOAAI
errJung, Wonyeong; Abdelnour, Arturo; Kaplonek, Paulina; Herrero, Rolando; Lee, Jessica Shih-Lu; Barbati, Domenic R.; Chicz, Taras M.; Levine, Kate S.; Fantin, Romain Clement; Loria, Viviana; Porras, Carolina; Lauffenburger, Douglas A.; Gail, Mitchell H.; Aparicio, Amada; Hildesheim, Allan; Alter, Galit; McNamara, Ryan P.
errShare
errSave
Recovering biomolecular network dynamics from single-cell omics data requires three time points
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2024-08-27
err0
errOAAI
errWang, Shu; Al-Radhawi, Muhammad Ali; Lauffenburger, Douglas A.; Sontag, Eduardo D.
errShare
errSave
Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection
errBRAIN
IF11.7
err2024-03-05
err2
errOAAI
errSpatola, Marianna; Nziza, Nadege; Irvine, Edward B.; Cizmeci, Deniz; Jung, Wonyeong; Van, Le Hong; Nhat, Le Thanh Hoang; Ha, Vu Thi Ngoc; Phu, Nguyen Hoan; Ho, Dang Trung Nghia; Thwaites, Guy E.; Lauffenburger, Douglas A.; Fortune, Sarah; Thuong, Nguyen Thuy Thuong; Alter, Galit
errShare
errSave
Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination
errNATURE COMMUNICATIONS
IF15.7
err2024-01-30
err2
errOAAI
errNziza, Nadege; Deng, Yixiang; Wood, Lianna; Dhanoa, Navneet; Dulit-Greenberg, Naomi; Chen, Tina; Kane, Abigail S.; Swank, Zoe; Davis, Jameson P.; Demokritou, Melina; Chitnis, Anagha P.; Fasano, Alessio; Edlow, Andrea G.; Jain, Nitya; Horwitz, Bruce H.; McNamara, Ryan P.; Walt, David R.; Lauffenburger, Douglas A.; Julg, Boris; Shreffler, Wayne G.; Alter, Galit; Yonker, Lael M.
errShare
errSave
AutoTransOP: translating omics signatures without orthologue requirements using deep learning
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2024-01-29
err0
errOAAI
errMeimetis, Nikolaos; Pullen, Krista M.; Zhu, Daniel Y.; Nilsson, Avlant; Hoang, Trong Nghia; Magliacane, Sara; Lauffenburger, Douglas A.
errShare
errSave
Beta-spike-containing boosters induce robust and functional antibody responses to SARS-CoV-2 in with distinct vaccines
errCELL REPORTS
IF6.9
err2023-11-01
err4
errOAAI
errDeng, Yixiang; Atyeo, Caroline; Yuan, Dansu; Chicz, Taras M.; Tibbitts, Timothy; Gorman, Matthew; Taylor, Sabian; Lecouturier, Valerie; Lauffenburger, Douglas A.; Chicz, Roman M.; Alter, Galit; McNamara, Ryan P.
errShare
errSave
Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-09-06
err8
errOAAI
errHerman, Jonathan D.; Atyeo, Caroline; Zur, Yonatan; Cook, Claire E.; Patel, Naomi J.; Vanni, Kathleen M.; Kowalski, Emily N.; Qian, Grace; Srivatsan, Shruthi; Shadick, Nancy A.; Rao, Deepak A.; Kellman, Benjamin; Mann, Colin J.; Lauffenburger, Douglas; Wallace, Zachary S.; Sparks, Jeffrey A.; Alter, Galit
errShare
errSave
What cannot be seen correctly in 2D visualizations of single-cell 'omics data?
errCELL SYSTEMS
IF7.7
err2023-09-01
err3
errOAAI
errWang, Shu; Sontag, Eduardo D.; Lauffenburger, Douglas A.
errShare
errSave
Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-07-03
err14
errOAAI
errLai, Rocky; Gong, Diana N.; Williams, Travis; Ogunsola, Abiola F.; Cavallo, Kelly; Arlehamn, Cecilia S. Lindestam; Acolatse, Sarah; Beamer, Gillian L.; Ferris, Martin T.; Sassetti, Christopher M.; Lauffenburger, Douglas A.; Behar, Samuel M.
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errSave
Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition
errCELL SYSTEMS
IF7.7
err2023-07-01
err7
errOAAI
errNetterfield, Tatiana S.; Ostheimer, Gerard J.; Tentner, Andrea R.; Joughin, Brian A.; Dakoyannis, Alexandra M.; Sharma, Charvi D.; Sorger, Peter K.; Janes, Kevin A.; Lauffenburger, Douglas A.; Yaffe, Michael B.
errShare
errSave
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19
errNATURE IMMUNOLOGY
IF27.6
err2023-06-15
err7
errOAAI
errKaplonek, Paulina; Cizmeci, Deniz; Kwatra, Gaurav; Izu, Alane; Lee, Jessica Shih-Lu; Bertera, Harry L.; Fischinger, Stephanie; Mann, Colin; Amanat, Fatima; Wang, Wenjun; Koen, Anthonet L.; Fairlie, Lee; Cutland, Clare L.; Ahmed, Khatija; Dheda, Keertan; Barnabas, Shaun L.; Bhorat, Qasim Ebrahim; Briner, Carmen; Krammer, Florian; Saphire, Erica Ollman; Gilbert, Sarah C.; Lambe, Teresa; Pollard, Andrew J.; Nunes, Marta; Wuhrer, Manfred; Lauffenburger, Douglas A.; Madhi, Shabir A.; Alter, Galit
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Róbert Langer
H-index: 262 · Papers: 2.0K
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George M. Whitesides
H-index: 233 · Papers: 1.5K
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Rudolf Jaenisch
H-index: 209 · Papers: 802
R
Ralph Weissleder
H-index: 200 · Papers: 1.6K
S
Steven P. Gygi
H-index: 195 · Papers: 1.0K
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