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Journal of Enzyme Inhibition and Medicinal Chemistry cover

Journal of Enzyme Inhibition and Medicinal Chemistry

IF5.4
Papers3438
Citations9132
Journal Papers 3437
Publication Date
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Integrated computational and experimental identification of a novel ML-IAP-targeting peptide with antiproliferative activity in leukaemia cells
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-28
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deleteYan Wan; Yaozhi Hu; Ye Hong; Yanming Zhang; Na Hu; Jinrong Yao; Wenhui Fu; Xiaotian Yang; Junshuai Yue
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Identification of Crocin I as a positive modulator of GSTP1 with potential relevance to prostate cancer
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-28
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deleteHao Qin; YuanYuan Wang; Yukai Yang; Haihong Fang; Yangbiao Li; Yuxiu Yang; Yinhua Xiong; Lin Zhang
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Molecular insights into triazole-based compounds for triple-negative breast cancer treatment
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-28
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deleteAhamed Vilangalil; Sindhu Priya E. S.; Sarad Pawar Naik Bukke; Sandhya V.; Nafeesa Meha; Chandrashekar Thalluri; Kasolo Daniel; Allan Amooti Ahikiriza
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Structure-based analysis reveals a hydrophobic pocket governing P2Y12 receptor agonist potency and selectivity
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-25
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deleteMatteo Pavan; Jihyun Lee; John C. Hancock; Paola Oliva; Masaki Terabe; Jinmyoung Joo; Kenneth A. Jacobson
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Structure-based rational design and biological evaluation of a quinazoline-based EGFR exon 20 insertion inhibitor
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-25
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deleteSooheum Jo; Hyunsoo Jang; Suin Kim; Jaebong Jang
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Cycloserine inhibits glutamate decarboxylase from Mycobacterium tuberculosis
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-21
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deleteJan Snášel; Jiří Dostál; Michal Tupec; Ondřej Bulvas; Iva Pichová
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Exploring novel isatin derivatives as SARS-CoV-2 3CLpro inhibitors
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-10
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deleteJian Song; Cai Shi; Boning Yang; Jingxiang Yang; Caifei Huang; Jiaqi Liu; Shuwen Wu; Shuyuan Mo; Jian Yang
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Cryo-EM structure-based discovery of etravirine as a specific inhibitor of PRMT5/pICln protein-protein interaction for prostate cancer treatment
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-08
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deleteZhixia Chi; Xueyong Xu; Zhihang Shen; Xuehong Deng; Bennett D. Elzey; Chenglong Li; Wen Jiang; Chang-Deng Hu
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Design of aptamer peptides for immunomodulation
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-09-02
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deleteArpan Chowdhury; Prajesh Shrestha; Vivekanandan Subramanian; Venkatesh Mayandi; Mukesh Mahajan; Seetharama D. Jois
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Exploration of novel hydroxamic acid-based candidates integrating chalcone scaffold cap as multitarget HDAC inhibitors: design, anti-prostatic cancer assessment, in silico docking and molecular dynamic simulation
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-27
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deleteAya I. Abd El-hameed; Ibrahim M. Salem; Rasha M. Allam; Mariem M. Arafat; Hossameldin A. Aziz; Zuhier A. Awan; Tarek S. Ibrahim; Omar Alshazly; Eman A. M. Beshr; Stefan Bräse; Mamdouh F. A. Mohamed
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Inhibition effects and binding interactions of epigallocatechin and gallocatechin on tyrosinase and their anti-melanogenesis activity
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-26
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deleteJianjun Zhang; Zheng Shi; Jiang Li; Kaiming Li; Fan Wu; Min Zhao; Rui Xie; Hongbin Luo
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Identification of a candidate PRODH allosteric inhibitor MBTP-15324: modulation of proline metabolite profiles and ECM-associated gene-expression changes in lung cancer cells
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-24
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deleteYuxuan Zhou; Dingyuan Bai; Zhihan Li; Ciqin Li; Chunqiong Li; Mengyao Chen; Cheng Guo; Jun Yan; Yonglong Han; Quanjun Yang
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Conformationally constrained 6‑aryl‑1‑(3,4,5‑trimethoxyphenyl)-1H-pyrazolo[3,4‑b]pyrazines as novel microtubule destabilizers: design, synthesis, and antitumor evaluation
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-20
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deleteZhu Guo; Yujing Zhang; Ping Zou; Caiyun Sun; Liya Cui; Gang Wang; Chao Wang
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Novel 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine derivatives: design, synthesis, and biological evaluation as potent tubulin polymerisation inhibitors with anticancer activity
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-13
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deleteJiake Gao; Yujing Zhang; Rui Qu; Qianqian Xu; Zhenjuan Sun; Liya Cui; Chao Wang
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Recent progress in small molecules targeting the acidic tumor microenvironment
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-04
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deleteYinuo Fu; Jiahui Song; Chenyang Yu; Yuxi Guo; Bowei Tang; Guangzhong Yang; Yongsheng Zheng; Qiang Wang
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Context matters in PROTAC design: navigating the trade-off between degradation and developability
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-04
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deleteBoxin Zhang; Yunfei Zhang; Bingxing Zhang; Jinrong Hu; Changhua Ke; Teng Wu; Meiyan Wei; Juan Xia; Mengzhou Wang; Qianqian Zhao; Lei Tian; Chengyuan Liang
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A novel approach to improving solubility of drugs: chelation-assisted solubility enhancement (CHASE)
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-07-27
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deleteTanPhat Nguyen; Nicola Bauer; Samer Gozem; Binghe Wang
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Exploration of tropocollagen unwinding by cathepsin K dimer with chondroitin 4-sulphate through microsecond timescale molecular dynamics
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-07-26
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deleteMengyi Shan; Yue Wu; Chen Jiang; Jing Chen; Gang Cheng; Lu-Ping Qin
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Design, synthesis, and biological evaluation of 6-aryl-3-(3,4,5-trimethoxyphenyl)imidazo[1,2-a]pyridine derivatives as novel tubulin inhibitors with potent anticancer efficacy
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-06-17
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deleteWen Xu; Yujing Zhang; Qianqian Xu; Haibo Zhao; Liya Cui; Chao Wang
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Discovery of a novel and potent KRASG12V-targeting peptide with antiproliferative activity against colorectal cancer cells
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-06-11
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deleteHai Zhang; Shudan Yang; Yuting Wang; Miao-Miao Niu; Jingjiang She
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