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Journal of Enzyme Inhibition and Medicinal Chemistry cover

Journal of Enzyme Inhibition and Medicinal Chemistry

IF5.4
Papers3419
Citations9132
Journal Papers 3421
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Recent progress in small molecules targeting the acidic tumor microenvironment
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-08-04
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deleteYinuo Fu; Jiahui Song; Chenyang Yu; Yuxi Guo; Bowei Tang; Guangzhong Yang; Yongsheng Zheng; Qiang Wang
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Context matters in PROTAC design: navigating the trade-off between degradation and developability
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IF5.4
delete2026-08-04
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deleteBoxin Zhang; Yunfei Zhang; Bingxing Zhang; Jinrong Hu; Changhua Ke; Teng Wu; Meiyan Wei; Juan Xia; Mengzhou Wang; Qianqian Zhao; Lei Tian; Chengyuan Liang
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Design, synthesis, and biological evaluation of 6-aryl-3-(3,4,5-trimethoxyphenyl)imidazo[1,2-a]pyridine derivatives as novel tubulin inhibitors with potent anticancer efficacy
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-06-17
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deleteWen Xu; Yujing Zhang; Qianqian Xu; Haibo Zhao; Liya Cui; Chao Wang
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Discovery of a novel and potent KRASG12V-targeting peptide with antiproliferative activity against colorectal cancer cells
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-06-11
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deleteHai Zhang; Shudan Yang; Yuting Wang; Miao-Miao Niu; Jingjiang She
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Lidocaine enhances antitumor effects of sorafenib and GW5074 in colorectal cancer cells
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-06-08
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deleteTzu-Chiao Lin; Zih-Syuan Wu; Shih-Ming Huang; Che-Wei Liu; Je-Ming Hu; Chia-Cheng Wen
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Design, synthesis, anticancer activity, and mechanistic investigation of 4,5,6,7-tetrahydrobenzo[b]thiophene carboxamides as CDK-2 inhibitors: in vitro and in silico DFT and molecular docking study
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-29
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deleteKurls E. Anwer; Ramadan M. Ramadan; Eman S. Nossier; Najla A. Altwaijry; Asmaa Saleh; Stefan Bräse; Ebtehal M. Husseiny
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Targeting the BMX in cancer: molecular mechanisms and emerging therapeutic strategies
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-29
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deleteMan Zhang; Jinchi Chen; Rong Liang; Wei Jiang; Min Lin; Siqi Wen; Dejun Liu; Bei Yi; Ruiqi Chen; Tianyu Chen; Zhao Li
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Discovery of azaindole/indole-fused pyrimidine tetracyclic scaffolds as novel potent CDK7 inhibitors
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-28
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deleteFan Pu; Axiao Tao; Pengxiang Qiu; Weishan Deng; Zijian Chen; Zheng Cao; Yunjiao He; Peng George Wang; Yan Zhang; Chengqing Ning; Xuechen Li; Jing Xu
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Systematic identification of bacterial neuraminidase inhibitors from Psoralea corylifolia using ultrafiltration-UPLC-Q-Orbitrap-MS and molecular dynamics
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IF5.4
delete2026-05-25
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deleteYu Jin Kim; Seol Jang; Youn-Hwan Hwang
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Design and Pictet–Spengler enabled synthesis of carboxamide-substituted imidazo[1,2-a]quinoxalines as dual EGFR and tubulin targeting anticancer agents
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-25
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deleteJoydeep Chatterjee; Gaurav Joshi; Vibhu Jha; Shivkanya M. Bhujbal; Shivani Rathour; Sanjana Majumdar; Muhammad Wahajuddin; Prasad V. Bharatam; Raj Kumar
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Discovery of ferulic acid carbamate derivatives as dual-targeting agents of BuChE and Nrf2 for Alzheimer's disease
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteLao, Kejing; Li, Yingze; Xiao, Yueyan; Sun, Ya; Dai, Yuxuan; Li, Huijin; Yang, Yang; Zhang, Yun; Wang, Jing; Li, Weize; Gou, Xingchun; Guan, Li
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Inhibition of prolyl-tRNA synthetase and efflux pumps as a dual-targeting strategy against multidrug-resistant bacteria
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteTambascia, Cristiane; Silva, Jaqueline Cristina; dos Reis, Barbara Carvalho; Camilo, Camila Fernanda Silva; Tairum Junior, Carlos Abrunhosa; Hancio, Thais; Correia, Valquiria Graia; Pilli, Ronaldo Aloise; de Godoy, Andre Schutzer; Laleu, Benoit; Sforca, Mauricio Luis; Rocco, Silvana Aparecida; Benedetti, Celso Eduardo; Mercaldi, Gustavo Fernando
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Pesticidal evaluation of novel dual-chiral N-cyano sulfiliminyl anthranilic diamides derivatives
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteLi, Xiaomin; Wang, Mukuo; Li, Shuying; Xie, Weibin; Jin, Ruyi; Xie, Yongtao; Zhou, Shaa; Xiong, Lixia; Yang, Na; Zhou, Sha
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Discovery of novel coumarin-containing triazolo[1,5-a]pyrimidine derivatives as potent ABCB1 inhibitor for modulation of multidrug resistance
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteHmone, Nan Ye; Tian, Xuefei; Zhou, Dandan; Min, Zhiyi; Zhao, Yingxue; Wang, Shuai; Chen, Fen-Er; Wang, Ziyu; Zhang, Xuyao
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Reactive oxygen species (ROS) research in drug discovery and drug delivery: Can the medium Be a Trojan Horse disguised as something benign?
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteBansal, Shubham; Wang, Binghe
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Diethyl Phthalate (DEP) as a potential osteosarcoma risk factor: a multi-omics study integrating network Toxicology, single-cell RNA sequencing, and molecular docking
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteYin, Shangqi; Liu, Wuzheng; Gao, Chunxiao; Li, Chunyan; Wu, Jun
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Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteSharma, Ram; Rana, Mandeep; Thakur, Amandeep; Ojha, Ritu; Mousavi, Seyyed Mojtaba; Dhingra, Ashwani; Nepali, Kunal
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Design, synthesis and anti-breast cancer activity evaluation of 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-based PARP1/ATR dual inhibitors
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteHe, Meng-Lan; Wang, Zong-Hao; Yao, Xia; Ye, Lu-Lu; Du, Bo-Qun; Wang, Chen-Chen; Chen, Yong-Hao; Wang, Xiao-Xian; Luo, Hui; Gao, Yuan; Ye, Xiang-Yang
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Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteTseng, Hui-Ju; Wu, Yi-Wen; Chen, Yan-Ling; Lin, Tony Eight; Fang-Chin, Yu-Ting; Wu, Yueh-Lin; Sung, Tzu-Ying; Yen, Shih-Chung; Hsieh, Jui-Hua; Hsu, Kai-Cheng; Pan, Shiow-Lin
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Investigation of exercise-mimetic bioactive molecules as modulators of MMP activity and expression in cancer cells
deleteJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
delete2026-05-23
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deleteVo, Ha Vy Thi; Patton, Geewoo Nam; Park, Jae Sung; Kim, Song Ja; Kim, Namdoo; Lee, Hyuck Jin
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