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Molecular Cancer Therapeutics

IF5.5
Papers9021
Citations19513
Journal Papers 10505
Publication Date
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Broad-Spectrum Efficacy of CEACAM6-Targeted Antibody-Drug Conjugate with BET Protein Degrader in Colorectal, Lung, and Breast Cancer Mouse Models
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IF5.5
delete2025-02-03
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deleteKogai, Hiroyuki; Tsukamoto, Shuntaro; Koga, Minaho; Miyano, Masayuki; Akagi, Tsuyoshi; Yamaguchi, Atsumi; Mori, Kiyoshi; Gotoh, Kunihito; Nakazawa, Youya
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CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues
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IF5.5
delete2025-01-27
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PREAI
deletePaget, James T.; Ward, Joseph A.; Mckean, Andrew R.; Mansfield, David C.; Mclaughlin, Martin; Kyula-Currie, Joan N.; Smith, Henry G.; Roulstone, Victoria; Li, Chunhei; Zhou, You; Hardiman, Thomas; Grigoriadis, Anita; Coon, Devin O'Brien; Irshad, Sheeba; Melcher, Alan A.; Harrington, Kevin J.; Khan, Aadil
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Blocking Feedback Immunosuppression of Antigen Presentation in Brain Tumor During Oncolytic Virotherapy with oHSV-mshPKR
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IF5.5
delete2025-01-10
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PREAI
deleteTsuboi, Nobushige; Rivera-Caraballo, Kimberly A.; Sahu, Upasana; Pacholczyk, Rafal; Douglass, Eugene; Johnson, Theodore S.; Wang, Qin; Kolhe, Ravindra; Hedrick, Catherine C.; Munn, David H.; Hong, Bangxing
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Denfivontinib Activates Effector T Cells Through the NLRP3 Inflammasome, Yielding Potent Anticancer Effects by Combination with Pembrolizumab
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IF5.5
delete2024-12-31
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deleteKim, Dong Kwon; Synn, Chun-Bong; Lee, Wongeun; Jo, Ha-Ni; Lee, Chai Young; Lee, Seul; Hwang, Joon Yeon; Kim, Youngtaek; Kang, Seong-san; Baek, Sujeong; Na, Kwangmin; Yang, Seung Min; Kim, Mi Hyun; Han, Heekyung; Han, Yu Jin; Kim, Jae Hwan; Park, So Young; Park, Young Joon; Lee, Gang-Taik; Choi, Su-Jin; Sohn, Jie-Ohn; Ye, Sang-Kyu; Lee, Jii Bum; Lim, Sun Min; Hong, Min Hee; Pyo, Kyoung-Ho; Cho, Byoung Chul
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First Results of Migoprotafib, a Potent and Highly Selective Src Homology-2 Domain-Containing Phosphatase 2 Inhibitor in Patients with Advanced Solid Tumors
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IF5.5
delete2024-12-31
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deleteJohnson, Melissa L.; Wolf, Beni B.; Wang, Judy S.; Philipovskiy, Alexander; Shapiro, Geoffrey I.; Bockorny, Bruno; Guo, Wei; Shen, Jinshan; Jen, Kai Yu; Lerose, Marybeth; Hunter, Tamieka Lauz; Padval, Mahesh; Schmidt-Kittler, Oleg; Bhatia, Namrata; Dubey, Sarita; Suchomel, Julia; Bendell, Johanna C.; Jauhari, Shekeab; Eng-Wong, Jennifer; Lin, Jessica J.
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All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin
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IF5.5
delete2024-12-31
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deleteMei, Bingjie; Li, Junyang; Wang, Dengfeng; Feng, Lu; Huang, Jianming; Zhang, Guonan
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OBI-992, a Novel TROP2-Targeted Antibody-Drug Conjugate, Demonstrates Antitumor Activity in Multiple Cancer Models
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IF5.5
delete2024-12-30
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PREAI
deleteLi, Wan-Fen; Chiang, Ming-Feng; Weng, Hao-Cheng; Yang, Jhih-Jie; Wu, Hsin-Shan; Wu, Szu-Yu; Chen, Yu-Jung; Lu, Chi-Huan; Tu, Jyy-Shiuan; Hsu, Ren-Yu; Shia, Chi-Sheng; Huang, Teng-Yi; Lai, Ming-Tain
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Preclinical Evaluation of an Anchored Immunotherapy Strategy with Aluminum Hydroxide-Tethered IL-12 in Dogs with Advanced Malignant Melanoma
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IF5.5
delete2024-12-23
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deleteBarbosa, Matheus Moreno Passos; Kamerer, Rebecca L.; Schmit, Joanna; Lopez, Angel J.; Uyehara, Rachel; Tighe, Robert; Battula, Sailaja; Kaufman, Howard L.; Fan, Timothy M.
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Inhibition of the Met Receptor Tyrosine Kinase Signaling Enhances the Chemosensitivity of Glioma Cell Lines to CDDP Through Activation of p38 MAPK Pathway (vol 8, pg 1126, 2009)
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IF5.5
delete2024-12-18
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deleteLou, Xiuqin; Zhou, Qibing; Yin, Ying; Zhou, Cheng; Shen, Yan
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Inhibition of PSF Activity Overcomes Resistance to Treatment in Cancers Harboring Mutant p53
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IF5.5
delete2024-12-18
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deleteTakayama, Ken-ichi; Sato, Tomohiro; Honma, Teruki; Yoshida, Minoru; Inoue, Satoshi
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STAT5 Activation Enhances Adoptive Therapy Combined with Peptide Vaccination by Preventing PD-1 Inhibition
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IF5.5
delete2024-12-11
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deleteFan, Aaron E.; Sultan, Hussein; Kumai, Takumi; Fesenkova, Valentyna I.; Wu, Juan; Klement, John D.; Bernstock, Joshua D.; Friedman, Gregory K.; Celis, Esteban
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Leveraging synthetic lethality for the development of novel cancer therapies
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IF5.5
delete2024-12-09
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deleteBriggs, Kimberly
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Progress, pitfalls and promise: the journey to effective and well tolerated DNA damage response inhibitor combinations in the clinic
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IF5.5
delete2024-12-09
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deleteYap, Timothy A.
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Leveraging conformational dynamics for improved selectivity James Watters
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IF5.5
delete2024-12-09
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deleteWatters, James
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OICR41103: a chemical probe for investigating DCAF1 function and therapeutic potential
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IF5.5
delete2024-12-09
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deleteNoureldin, Mahmoud; Kimani, Serah; Wilson, Brian; Halabelian, Levon; Al-awar, Rima
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An integrative approach to nanomedicine: Leveraging new tools to advance drug delivery
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IF5.5
delete2024-12-09
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deleteBoehnke, Natalie
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Evaluation of natural and synthetic compounds on epithelial to mesenchymal transition in triple negative breast cancer
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delete2024-12-09
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PREAI
deleteFaruk, Asef; Patel, Saloni; Hallak, Ramez; Flaherty, Patrick; Cavanaugh, Jane
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Discovery of brain-penetrant inhibitors for the treatment of BRAF mutant tumors
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IF5.5
delete2024-12-09
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PREAI
deleteKahn, Dean
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Liposomal topotecan with low-intensity focused ultrasound utilization to improve drug penetration with brain parenchyma in pediatric brain tumors
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IF5.5
delete2024-12-09
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PREAI
deleteMangoli, Avani; Kim, Sarah; Blethen, Kathryn; Everhart, Angela; Nikiforov, Sasha; Grant, Gerry; Avigliano, Luke
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Design and deciphering of precision peptide inhibitors for cancer stemness using generative deep learning and molecular dynamics simulations
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IF5.5
delete2024-12-09
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deleteSelvaraj, Gurudeeban; Kaliamurthi, Satyavani; Peslherbe, Gilles H.
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