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Medical Hypotheses

IF0.8
Papers147
Citations8791
Journal Papers 147
Publication Date
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The role of spinal cord pulsatility in the pathogenesis of Post-traumatic syringomyelia: A novel hypothesis
deleteMedical Hypotheses
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delete2026-04-01
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deleteXu, Feifan; Jian, Fengzeng; Guan, Jian; Yi, Zhiqiang; Wang, Xingwen
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From cellular cognition to psychopathology: a three-level framework of biological decision-making
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deleteGuerrero, Gaston Lenin Nole
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Osteoclasts may play key roles in initiating vascular calcification during atherosclerosis
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deleteLiu, Yuxiao; Wu, Jingqi; Chen, Jingrong; Zhang, Hongmei; Li, Mingzheng
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A substrate-competition hypothesis for type 2 diabetes driven by nutrient excess rather than a primary insulin-signaling defect
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deletePoothullil, John M.
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Temporal coding instability in tinnitus: The temporal jitter hypothesis
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deleteSevmez, Halime Sumeyra
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The mechanical protector paradox: a hypothesis linking transition zone enlargement, urethral angle, and carcinogenesis via intraprostatic reflux
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deleteLin, Yu-Hsiang; Lin, Po-Ting; Teng, Tzu-Chi; Chen, Yu-Ting; Hou, Chen-Pang; Chen, Jau-Yuan; Chen, Chien-Lun
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Myocardial cell-derived exosomal miR-155-5p promotes depressive disorders in CVD via microglial SIRT1 pathway
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deleteNing, Meng; Zhang, Zhibin; Zheng, Chenguang
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An environmental-sensorimotor cascade hypothesis: Spatial and mechanical affordances shape segmental trunk control in preterm infants
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delete2026-04-01
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deleteTapanya, Weerasak; Sangkarit, Noppharath
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Could early-life caffeine exposure program preterm infants for later-life caffeine dependence? A mechanistic hypothesis
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deleteCan, Emrah; Gok, Cagri Cumhur
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Aquaporin dysregulation and persistent hyperosmolar microenvironments as a barrier to tissue recovery
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deleteSarkozy, Susie
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Delayed acclimatization and persistent hyperdynamic circulation amplify capillary stress in severe high-altitude illness
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delete2026-03-01
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deleteGabbay, Uri; Carmi, Or
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A novel multilayered drug-releasing stent for actively accelerating thrombosis in aneurysm therapy
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deleteZhang, Peng; Deng, Xiaoyan; Liu, Xiao; Zhang, Fan; Li, Jun; Guo, Chun; Liu, Shangming
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Neuro-entero-cardiac bridge: could gut-derived catecholamine-loaded extracellular vesicles synchronize the pathogenesis of Parkinson's disease, irritable bowel syndrome, and stress-triggered arrhythmias?
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delete2026-02-01
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deleteUgwu, Okechukwu Paul-Chima; Basajja, Mariam; Ogenyi, Fabian C.; Ugwu, Chinyere N.; Ben Okon, Michael; Mundu, Mustafa M.
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Post-menopause cardiovascular risk - lack of hormones or bleeding? - Increased blood viscosity due to cessation in menstrual bleeding
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deleteFinlayson, Erik
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Iron chelators reduce prostaglandins and leukotrienes by inhibiting cyclooxygenase and lipoxygenase: A hypothesis to attenuate PPARγ transcriptional activity in prostate cancer
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deleteNoulsri, Egarit; Lerdwana, Surada
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Regarding the counterintuitive finding of vigorous physical activity and increased carotid plaque vulnerability
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deleteGoldstein, Mark R.; Mascitelli, Luca
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Thermal Compartment Syndrome: A hypothesis of iatrogenic intracranial heat entrapment during neurosurgical procedures
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delete2026-02-01
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deletePuljiz, Marko; Ores'kovic, Darko; Moretti, Marko; Bitunjac, Andrija; Vrtaric, Vjenceslav; Puljiz, Simun; Puljiz, Fani; Kastelancic, Andelo; Almahariq, Fadi; Marinovic, Tonko; Chudy, Darko
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The Voided Volume Transit Point (VVtrans): a novel functional biomarker for staging bladder decompensation in bladder outlet obstruction
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delete2026-02-01
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deleteLin, Yu-Hsiang; Lin, Po-Ting; Lin, Kuo-Jen; Teng, Tzu-Chi; Chen, Yu-Ting; Hou, Chen-Pang; Chen, Chien-Lun
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Fibroblast-to-myofibroblast differentiation in gut wall and abdominal soft tissue corrupts normal bowel function in irritable bowel syndrome: A hypothesis
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deletePlaut, Shiloh
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DNA as life's archive: unraveling the molecular storage of memories and information
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deleteYasseen, Akeel Abed; Jumaah, Alaa Salah; Nafakhi, Hussein
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