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Genes & Diseases

IF9.4
Papers400
Citations
Journal Papers 394
Publication Date
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Advances in molecular and gene-based therapies for phenylketonuria: Mechanisms, therapeutic strategies, and clinical translation
deleteGenes & Diseases
IF9.4
delete2026-10-05
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deleteOAAI
deleteJing Wang; Jing Yan; Ying Liu; Jiaojiao Yin; Jianying Pei; Chong Zhang
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AI-driven precision medicine for lysosomal storage disorders: Innovations in diagnosis and therapeutics
deleteGenes & Diseases
IF9.4
delete2026-10-05
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deleteRahaf M. Ahmad; Batool M. Ahmad; Feda E. Mohamed; Muhammad Jalal Khan; Fatma Al-Jasmi; Bassam R. Ali
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APT1-mediated depalmitoylation of CLDN7 promotes clear cell renal cell carcinoma progression via ubiquitin-proteasomal degradation and epithelial-mesenchymal transition
deleteGenes & Diseases
IF9.4
delete2026-10-03
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deleteJieping Yang; Ran Li; Xuanjun Guo; Jilong Zhang; Tai Tian; Shuoyu Wang; Cong Huang; Yue Li; Yucai Wu; Shiming He; Cuijian Zhang; Yanqing Gong
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Beyond tumor cell–intrinsic metabolism: Hexokinase 2 as a central regulator of the tumor microenvironment
deleteGenes & Diseases
IF9.4
delete2026-10-03
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deleteXin Wang; Huadong Pei; Feng Yao; Shiya Zhu; Sihao Zheng
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AI-driven multi-omics integration reveals PSMD10 as a regulator of lipid metabolic reprogramming and ferroptosis vulnerability in metastatic pancreatic ductal adenocarcinoma
deleteGenes & Diseases
IF9.4
delete2026-10-01
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deleteJiamin Zhang; Jingyuan Ning; Shu Fang; Yong Han; Mai Li; Wenyue Chen; Tianyu Dong; Qing Bai; Miaomiao Jia; Peipei Hao; Huixian Cui
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The fragility and dual biological functions of PARK2 in neuroinflammation and tumorigenesis
deleteGenes & Diseases
IF9.4
delete2026-09-30
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deleteChuangdong Ruan; Penghui Yang; Zhiqing Liang; Jinxun Huang; Jiawen Li; Rongxin Zhang; Yan Li
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Plakophilin 3 promotes pancreatic cancer progression by upregulating P120-catenin and facilitating M2 macrophage polarization and immune microenvironment reprogramming
deleteGenes & Diseases
IF9.4
delete2026-09-30
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deleteXiaojia Li; Linyu Zhang; Hailin Jiang; Qiang Luo; Siyan Tan; Qiqi He; Shuguang Wu; Shaojiang Zheng; Keping Xie; Dacheng Xie
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Protein ATG8ylation: A self-regulatory feedback loop in the autophagy machinery
deleteGenes & Diseases
IF9.4
delete2026-09-29
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deleteXiao-Yu Qi; Jing Zhang; Yang Wang
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Cell-type specific signatures of regional brain vulnerability in COVID-19
deleteGenes & Diseases
IF9.4
delete2026-09-29
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deleteTao Liu; Yizhen Pan; Haowen Li; Xiaoyan Jia; Shiyuan Zhang; Zhiqi Lee; Iris Y. Zhou; Xulin Chen; Mohamed Gamal Eldin Abd El Hamid Elashhab; Lei Shi; Weijun Qin; Keying Zhang; Lijun Bai; Zhuonan Wang
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TfR1 deficiency beyond combined immunodeficiency. Pivotal role of mitochondrial function and iron-sulfur cluster biogenesis in disease pathogenesis
deleteGenes & Diseases
IF9.4
delete2026-09-29
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PREAI
deleteMunoz-Pujol, Gerard; Huisman, Elise J.; Mesa, Juan-Francisco; Joosten, Marieke; Devos, Annick; Fernandez-Burriel, Miguel; Ugarteburu, Olatz; Segur-Bailach, Eulalia; Gea-Sorli, Sabrina; Moliner, Sonia; Farre-Tarrats, Laia; Guitart-Mampel, Mariona; Arauz-Garofalo, Gianluca; Gay, Marina; Villamor, Neus; Martin, Gemma; Calvo, Maria; Garrabou, Gloria; Macias, Maria J.; Gort, Laura; Garcia-Villoria, Judit; Fillat, Cristina; Tort, Frederic; Ribes, Antonia
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Co-localization of TAZ and H2A.Z up-regulates IL-6 expression in alveolar epithelial cells to polarize M2 cells to alleviate hypoxia-induced lung injury
deleteGenes & Diseases
IF9.4
delete2026-09-29
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PREAI
deleteLiu, Paiyu; Zhang, Mengjie; Zeng, Jitao; Gao, Yafei; He, Xiaochong; Liu, Wenying; Wang, Peng; Ni, Bing
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Aberrant sialylation in cancer: From molecular mechanisms to potential therapeutics
deleteGenes & Diseases
IF9.4
delete2026-09-29
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PREAI
deleteKong, Ran; Wang, Cong; Zhang, Yu; Zhong, Guangcai; Liu, Jiarui; Zhou, Xiangxiang
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Lyn promotes liver metastasis of colorectal cancer by regulating TRIB3 through super-enhancers and mediating SOX9 phase separation
deleteGenes & Diseases
IF9.4
delete2026-09-28
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deleteZhenyu Zhang; Xiaoqi Yu; Kexin Jiang; Bo Wang; Chaofan Hou; Yangmeng Guo; Yu Xin; Meihui Shu; Liang Ye; Jing Chai; Shuangyi Ren; Yunfei Zuo
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First report of phenotypic heterogeneity in a congenital fiber-type disproportion pedigree
deleteGenes & Diseases
IF9.4
delete2026-09-26
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deleteSha Wang; Ling Wang; Jianwu Zhou; Hongdong Li; Yuyu Long; Li Jiang; Xiaoyu Xiong
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Extracellular nonstructural protein 1 of human respiratory syncytial virus during the early infection phase is associated with a TH2-related immune response, contributing to disease severity in human infants
deleteGenes & Diseases
IF9.4
delete2026-09-26
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deleteShi Mo; Luo Ren; Yu Gao; Sisi Chen; Jun Xie; Xiaoru Long; Xiaohong Xie; Xiang Wen; Na Zang; Yu Deng; Enmei Liu; Leiqiong Gao
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Hla of Staphylococcus aureus suppresses TRAF6 K63-linked ubiquitination to promote intracellular persistence
deleteGenes & Diseases
IF9.4
delete2026-09-26
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deleteLeilei Qin; Haotian Zhou; Yaji Yang; Jianye Yang; Qianshui Hu; Lin Yang; Shuhao Yang; Feilong Li; Mo Jing; Liqun Zhao; Huirong Pan; Ling Zeng; Wei Huang; Hao Zeng; Ning Hu
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Macrophage-derived ECM1 potentiates integrin β3-dependent HIF activation and matrix remodeling in human lung fibrosis
deleteGenes & Diseases
IF9.4
delete2026-09-26
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deleteXi Li; Yilu Zhou; Siyuan Wang; Kun Zheng; Franco Conforti; Robert Ridley; Laura R. Sadofsky; Rob M. Ewing; Tim Wallis; Ben G. Marshall; Aiman Alzetani; Donna E. Davies; Mark G. Jones; Yihua Wang
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tRNA-derived small RNAs in central nervous system diseases: Regulatory mechanisms and clinical translation potential
deleteGenes & Diseases
IF9.4
delete2026-09-26
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deleteBing Yu; Yifan Xu; Jinpeng Wu; Junshan Wan; Zhongxiang Guo; Chonghui Zhang; Chao Wang
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Glioma stemness as an integrated cellular and functional state: Niche coupling, plasticity, and therapeutic implications
deleteGenes & Diseases
IF9.4
delete2026-09-26
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deleteYonglin He; Zhipeng Liao; Chen Wang; Yawen Pan; Weilin Jin; Liang Niu
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Single-cell insights into hypertensive adipose tissue: Metabolic reprogramming, immune dynamics, and the PPARγ/CBR3 axis
deleteGenes & Diseases
IF9.4
delete2026-09-25
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deleteXianglin Long; Jun Xiao; Zhulu Chen; Fangyan Tan; Shunkang Rong; Jing Wang; Weiran Dai; Ling Zhang; Qiang She; Xin Yuan; Jianlin Du
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