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ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5
Papers225
Citations
Journal Papers 221
Publication Date
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The Synthetic Role of PFAS in Drug Substance Manufacturing: An IQ Consortium Working Group Review on the Potential Impact of PFAS Restrictions on Patient Access to Medicines
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteGemma Scotney; Kenneth J. Fraunhoffer; Ankur Jalan; Dazhan Liu; Andreas R. Rötheli; Robert Toner; Jonathan C. Tripp; Xin Yao
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Lipophilic Salts of High Melting Point Drugs Modulate Solid-State Properties and Organic Solubility to Enable Manufacturability of Amorphous Solid Dispersions
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteStella P. Petrova; Matthew M. Behymer; Naga K. Duggirala; Aaron Goodwin; Dana E. Moseson-Tarrh; Lynne S. Taylor
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Electrochemical Synthesis of Renewable Pyridines via Oxidative Ring Expansion
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteSilja Hofmann; Astrid Kjær Steffensen; Alexandros Xanthopoulos; Anders Riisager; Helena Lundberg; Tobias Ankner
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An Aryl Alcohol Oxidase-Peroxygenase Catalyst System Enables Efficient Alcohol to Aldehyde Transformation
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteYutong Wang; Nure Celebi; Paul Kerstholt; Sebastian Govaerts; Vlada B. Urlacher; Miguel Alcalde; Frank Hollmann
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Improved Synthesis of a Key Intermediate of Onapristone
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-08
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PREAI
deleteFei Lv; Qihua Zhao; Jiaoyang Feng; Ziyang Jia; Erin Zebrowski; Anjiang Yang; Boyu Zhong; Tony Yantao Zhang
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Some Items of Interest to Process R&D Chemists and Engineers
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-07
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deleteThomas Verheyen; Paul F. Richardson; Andrei A. Zlota; Robert B. Kargbo; Alan Steven; David S. B. Daniels; Christopher C. Nawrat; Alexandre Barthelme; Sylvain Guizzetti; John Kremers; John Knight
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Process Development of the RIPK1 Inhibitor Oditrasertib Part 1: Continuous Synthesis of the Pyridine Core
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-06
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PREAI
deleteGrace P. Ahlqvist; Nicholas L. Reed; Eileen M. Hoang; Boung Wook Lee; Douglas G. Fraser; Christopher P. Breen; Maia D. Carvalho; Sean Breen; Kiersten Campbell; Shruti Kumta; M. Grace Russell; Robert Yule; Brenda J. Burke; Jason S. Tedrow
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Development of a Scalable Synthesis for the Spirocyclic Benzoxepane–Pyridine Core of FXR Agonist HEC96719
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-01
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PREAI
deleteJiayang Zhang; Junwen Wu; Shengqiang Pan; Hong Chen; Zhongqing Wang; Xiaoyun Lu; Xinye Yang; Yingjun Zhang
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Development of a Commercial Manufacturing Process for Ganaplacide Phosphate
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-01
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PREAI
deleteAlexandre Leclair; Thomas Ruch; Jibin Zhao; Xingxian Gu; Navid Dastbaravardeh; Xufan Wang; Jiong Ye; Zichen Jia; Andreas Kordikowski; Christian Mueller; Liqun Zhao; Jianguang Zhou; Serge Konrad
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Four-Step Continuous-Flow Total Synthesis of 4-Chloro-6; 7-dimethoxyquinoline; a Key Intermediate for Tyrosine Kinase Inhibitors
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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PREAI
deleteXiaobin Liang; Xiaorong Zhou; Yian Luo; An Su; Hanqi Zhou; Jianli Chen; Fengfan Liu; Weike Su
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Case Studies on Enabling Data-Rich; Parallelized Kinetic Analysis for Process Optimization with the ReactALL Platform
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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PREAI
deleteVaishnavi N. Nair; Andreas R. Rötheli; Alan H. Cherney; Madeleine C. Deem; Melodie Christensen; Kevin Stone; Lu Han; Sebastien Monfette; Truong N. Nguyen
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Celebrating Lilly: 150 Years of Being a Medicine Company
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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deleteOAAI
deleteSarah O’Keeffe; Sarah E. Langan; Scott A. Frank; Qiang Yang
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Hydrogenation Process Development in a Data-Rich Environment
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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PREAI
deletePeter Sagmeister; Kensaku Matsunami; Giovanni Aprile; Darren A. Whitaker; Mohammed Janoudi; Thomas Toupy; Adrian Ramirez Galilea; Neda Nazemifard; Charles D. Papageorgiou; Aparajith Bhaskar; John Mack; Richard D. Braatz; Allan S. Myerson
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Heterogeneous Photochemical Process Intensification: Crystallization-Induced Dynamic Resolution of Amines
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-29
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deleteJonathan M. Meinhardt; Jiang Wang; Yufei Wei; Daniel P. Walker; Robert R. Knowles
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Development of a Second-Generation Stereoselective Manufacturing Process for a Key N-Hydroxyamidine Intermediate of GDC-6599 Enabled by Data Science and Mechanistic Understanding
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-29
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PREAI
deleteJacob C. Timmerman; Allen Y. Hong; Kurt Püntener; Anna-Lena Glass; Sandro Tonazzi; Katarzyna A. Piechowicz; Maud Guillemot-Plass; José G. Napolitano; Breanna Conklin; Haiming Zhang; Francis Gosselin
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Scalable Preparation and Application of Ar2S+-CF3 TfO–
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-26
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PREAI
deleteJia-Shuo Liu; Jin-Hong Lin; Ji-Chang Xiao
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Kilogram-Scale Process Development of Formoterol Fumarate: Synthesis; Identification; and LC–MS/MS Method Development for Trace-Level Quantification of N-Nitroso Impurity
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-26
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PREAI
deleteKishor More; Vinayak Vele; Rajesh Kamath; Mustapha Mandewale; Mohan Anand Chandavarkar
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Scalable Synthesis of a Biaryl RASG12C Cancer Inhibitor as a Single Atropdiastereomer
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-26
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PREAI
deleteChristopher D. Parsons; Carl J. Mallia; Miriam Turner; Rachel H. Munday; Steven D. Bull
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A Practical and Scalable-Oriented Enantioselective Synthesis of (S)-Autumnaline
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-25
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deleteAlessandro Brusa; Matteo Bottiglieri; Carola Tomassi; Francesco Feola; Daniele Lanaro; Andrea Bonetti; Gabriella Zappia; Federico Sala; Andrea Gambini; Mario Falzoni; Pietro Allegrini; Maria Luisa Gelmi; Massimiliano Aschi; Andrea Mazzanti; Fabio Pesciaioli; Armando Carlone
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Optimization of a Resolution Process Allowing Access to Both Enantiomers of the Versatile Chiral Phosphine Ligand sSPhos on Scale
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-25
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deleteOAAI
deleteHamzah Sharif; Thomas D. Svejstrup; Staffan Karlsson; Robert J. Phipps
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