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CPT-Pharmacometrics & Systems Pharmacology

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Journal Papers 123
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Aflibercept 8 mg: From Ocular Clearance to Pharmacodynamic Duration
delete2026-10-11
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deleteDaniele Veritti; Valentina Sarao; Paolo Lanzetta
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Application of an Open-Source Modular Framework for Pharmacokinetic, Pharmacodynamic, and Safety Simulations to Anti-Tuberculosis Drugs
delete2026-10-07
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deleteMarco Siccardi; Nina Nauwelaerts; Raphaëlle Lesage; Diane Lefaudeux; Vanessa Baier; Venetia Karamitsou; Cleo Demeester; Miao-Chan Huang; Alexander Kulesza; Stephan Schaller
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Simultaneous Population PKPD Analysis of Belantamab Mafodotin, Soluble BCMA, and Serum M-Protein in Relapsed/Refractory Multiple Myeloma
delete2026-09-30
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deleteJohn D. Clements; Inmaculada C. Sorribes; Josh Kaullen; Christine Neumar; Adekemi Taylor; Mun Sang Yue; Xi Chen; Herbert Struemper; Geraldine Ferron-Brady
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Population Pharmacokinetics of Dolutegravir in Plasma and Cerebrospinal Fluid in Adults Living With HIV
delete2026-09-30
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deleteMohammed W. Ali; Sam Nightingale; Tracy Kellermann; John Joska; Alan Winston; Saye Khoo; Joseph F. Standing; Eric H. Decloedt; Ahmed A. Abulfathi
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Development, Early Verification and Application of a North American Pediatric PBPK Model, Comparison With the North European Pediatric Population
delete2026-09-25
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deleteTrevor N. Johnson; Fiskani Kondowe; Joyce van der Heijden; Saskia N. de Wildt; Iain Gardner; Karen Rowland Yeo
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Population Pharmacokinetics of Topical Timolol Maleate Gel in Healthy Volunteers and Infants With Superficial Infantile Hemangioma
delete2026-09-21
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deleteLi Li; Yanming Li; Fan Hu; Deming Wang; Ning Sun; Qingheng Meng; Qin Yu; Ling Xu; Libo Zhao; Lin Ma
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A Quantitative Systems Pharmacology Model of Human Leucine Metabolism
delete2026-09-18
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deleteJ. Cody Herron; Anna Sher; Yingbo Ma; Elisabeth Roesch; Sebastian Miculța-Câmpeanu; Christopher Rackauckas; Kevin J. Filipski; Rachel Roth Flach; Theodore R. Rieger; Cynthia J. Musante; Richard Allen
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Pharmaceutical Industry Perspectives on Exposure-Response Confounding in Large Molecule Therapeutics: Results From an IQ Consortium Survey
delete2026-09-16
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deleteEngie Salama; Manisha Lamba; Sihem Ait-Oudhia; Ellen Wang; Dorothee Semiond; Zhang Li; Tao Long; Satyendra Suryawanshi; Leticia Arrington; Wei Gao; Xiaowen Guan; Hugh Giovinazzo; Dale Miles; David C. Turner
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Transporter-Drive Interstitial Tissue Exposure and Pharmacodynamic Response of Meropenem in Sepsis: A Mechanistic PBPK Modeling Study
delete2026-09-16
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deleteLaura Ben Olivo; Jessica Luisa Silva de Lemos; Vinicius Jardim Rodrigues; Bibiana Verlindo de Araújo
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Integrating CRRT as a Virtual Organ Into Physiologically Based Pharmacokinetic Modeling to Optimize Antimicrobial Dosing in Septic Patients
delete2026-09-16
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deleteYuanming Xing; Yijing Zhang; Chuqi Bai; Yulan Qiu; Chuhui Wang; Lei Chen; Taotao Wang; Jiaojiao Chen
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Development of Integrated Parent–Metabolite Pharmacokinetic Model With Apparent Presystemic Metabolism to Characterize the Disposition of Alverine
delete2026-09-16
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deleteAra Cho; Hyeon-Cheol Jeong; MinJu Kim; Inkyung Cho; Hyeon-Jeong Na; Kyong-Cheol Ko; Yoon-Jee Chae; Kyeong-Ryoon Lee
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Model-Based Tacrolimus Dosing Using the Population Pharmacokinetic Analysis Under the Nirmatrelvir/Ritonavir Therapy
delete2026-09-16
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deleteKotaro Itohara; Yoshiki Katada; Takahiro Hatayama; Toshiaki Igarashi; Jiro Ogura; Tomoki Fukushima; Shingo Yamazaki; Masato Homma; Takashi Niwa; Yoshiaki Kato; Nanae Yamamoto; Hideyuki Terazono; Hideo Shiohira; Tomohiro Terada; Ikuko Yano
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