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BIOORGANIC & MEDICINAL CHEMISTRY

IF3
Papers188
Citations
Journal Papers 187
Publication Date
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Selective PTP1B inhibition by A-1331852: Uncompetitive kinetics and computational evidence for C-terminal engagement
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-03
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deleteOAAI
deleteNathaly Vasquez-Martínez; Alejandro Sosa-Peinado; Francisco Cortés-Benítez; Martín González-Andrade
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Targeting the putative allosteric site J of cannabinoid receptor type 2 with peptide modulators: From mechanistic investigation to candidate identification
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-02
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PREAI
deleteXinyi Zhang; Zhihui Chen; Mengxiang Su
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Pyridine-core scaffolds suppress A549 lung cancer cell progression: Evaluation of the antiproliferative activity, apoptosis, ROS generation, clonogenic suppression, and EGFR expression
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-01
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PREAI
deleteK.B. Sachin Kumar; N.D. Satyanarayan; L. Vedavi; H. Vishwas; H.M. Kumaraswamy
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Synthesis of vincamine derivatives via Pictet-Spengler reaction leads to additional unexpected oxidized spirocyclic byproducts - initial investigations in cytotoxic, anti-diabetic, enzyme inhibition as well as anti-herbivore activities
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-30
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PREAI
deleteChristina Rodler; Dominik Wenisch; Zehra Özel; Michael Jakupec; Johann Schinnerl; Lothar Brecker
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Neutral sphingomyelinase 2 inhibitors based on the imidazo[1,2-b]pyridazin-3-amine scaffold
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-30
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PREAI
deleteBiswajit Kundu; Ajit G. Thomas; Matthew Stremlau; Ayush Bajaj; Louis Mueller; Arina Ranjit; Rana Rais; Barbara S. Slusher; Takashi Tsukamoto
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Synthesis of axially chiral benzochalcogenophene derivatives and their anti-proliferative activities in cancer cells
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-29
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PREAI
deleteKanon Nakaie; Takumi Inoue; Rinko Mikyu; Nanami Otsuki; Eishi Ashihara; Takumi Furuta
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Hypoxia-activated 2-nitroimidazole-brusatol carbonate prodrugs for enhanced gastric cancer therapy with reduced systemic toxicity
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-28
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PREAI
deleteJichong Li; Xuelan Ma; Zijian Liu; Xinyu Chang; Yifan Wei; Ning Ma; Xiaoling Liu; Xuan Zhang; Yiwei Sun; Hao Zhou; Qingbo Liu; Shao-Jiang Song
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Criteria-guided selection of alternative zinc-binding groups of HDAC3 inhibitors using in silico and in vitro approaches
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-25
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deleteThabo Brighton Makgoba; Samuel Egieyeh; Erika Kapp; Jacques Joubert
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Rivastigmine-centered molecular hybridization strategies for multi-targeted intervention in Alzheimer's disease: Advances (2020–2026)
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-25
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PREAI
deleteNitin Kumar; Virendra Kumar Kushwaha; Gourav Singh; Smriti Ojha; Alok Kumar Dash; Gauri Shankar
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Design, synthesis, and biological evaluation of novel dihydropyrimidinone imines as potent anticancer agents targeting AKT to induce cell cycle arrest and apoptosis in breast Cancer cells
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-23
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PREAI
deleteMarian N. Gerges; Ahmed A. Noser; Eman G. Ibrahim; Thoria Diab
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Design, synthesis and biological evaluation of a series of new, potent FLT3 PROTAC degraders with rigid linkers
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-19
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PREAI
deleteLicheng Zhou; Yinglong Chen; Jiahe Li; Yayuan Yang; Wenyan Liu; Yingfan Liu; Bohai Fan; Yang Zhou; Jinwei Zhang; Xiaomei Ren; Ke Ding; Weixue Huang; Zhen Wang; Fengtao Zhou
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Redirecting MurD inhibitor preference toward MurD2 through glutamate stereochemical inversion
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-15
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PREAI
deleteZhuang Qian; Yu Nakashima; Tohru Dairi; Hiroyuki Morita
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Design, synthesis, biological and computational evaluation of Thieno[3,2-d] pyrimidine-based inhibitors of JAK3 kinase
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-12
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PREAI
deletePoowadon Fukasem; Kittitat Jaengwang; Duangkamol Gleeson; Robert G. Britton; Kiattawee Choowongkomon; M. Paul Gleeson
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An in vitro comparative study of cefiderocol, siderophore-aztreonam and siderophore-daptomycin conjugates against select gram-negative bacteria
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-11
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deleteRui Liu; Patricia A. Miller; Marvin J. Miller
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Structural optimization of 2-(2-aminopyridin-4-yl)-N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as potent interleukin-1 receptor-associated kinase 4 inhibitors
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-06
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PREAI
deleteHiroshi Inami; Junko Watanabe; Naohiro Aoyama; Hiroyuki Usuda; Tsuyoshi Mizutani; Hisashi Hayashida; Tomonori Ito; Emiko Imamura; Takeshi Ishikawa
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Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1 inhibition: Synthesis, biological evaluation, and preliminary in Vivo studies
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-02
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deleteAjay L. Chandgude; Giovanni Loriga; Andrea Beccu; Fabio Arturo Iannotti; Ester Pagano; Raffaele Capasso; Riccardo Fusco; Pietro Spanu; Fausta Ulgheri; Alexander Domling
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Design, synthesis and evaluation of fluorinated CYP1B1 inhibitors based on a trans-stilbene scaffold
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-02
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PREAI
deleteMeixian Yang; Xin Liu; Xin Wei; Dachuan Qiu; Weijuan Chen; Jiajing Cai
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Functionalization of cyclotriveratrilene with tetrazole and phenothiazine for doxorubicin coordination and delivery
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-01
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PREAI
deleteReddy, Nallagari Bharath Sagar; Rengamanar, Haritha; Wani, Shabir Hyder; Zainab, Quaryia; Tang, Chih-Hsin; Coluccini, Carmine
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An HOCl-activated chemiluminescent prodrug enabling self-reporting camptothecin release and imaging-guided therapy in peritoneal metastasis
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-01
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PREAI
deleteZhou, Yanhan; Wang, Hongchao; Yang, Maocheng; Li, Hongyu; Yuan, Zeli; Gao, Jie
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A sustainable approach to 1,3-Oxathiolan-5-ones and their identification as a new anthelmintic scaffold
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-01
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PREAI
deleteLorenzo, Fernando J.; Veuthey, Tania V.; De Rosa, Maria Jose; Ocampo, Romina A.; Gerbino, Dario C.
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