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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IF2.2
Papers189
Citations
Journal Papers 187
Publication Date
Structure activity relationship studies of alkynyl 6-nitroquinoxalines as potential anti-tuberculosis agents
delete2026-10-07
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deleteBlesant K. Maluleke; Emmanuel N. Agbo; Ogunyemi O. Oderinlo; Winston. Nxumalo
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Design, synthesis, and preliminary in vitro screening of novel tolmetin hydrazones against colon cancer
delete2026-10-02
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PREAI
deleteEcem Gökoğlan; İrem Atlihan; Alimet Sema Özen; Pinar Mega Tiber; Özgür Yilmaz; Ş. Güniz Küçükgüzel
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Discovery and characterization of potent and efficacious small-molecule parathyroid hormone Receptor-1 (PTH1R) antagonists for the treatment of hypercalcemia
delete2026-10-01
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PREAI
deleteJoseph Pontillo; Shimiao Wang; Yunfei Zhu; Elizabeth Rico-Bautista; Jonathan Shintaku; Sameer Urgaonkar; Agnes Antwan; Stephen F. Betz
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Uncovering the importance of lipofection for aptamer-mediated therapeutic oligonucleotide delivery in a HER2+ SKBR3 breast cancer cell line
delete2026-09-30
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PREAI
deleteJoshua O'Grady; Filiz K. Collak; Matthew Reynolds; Bruce C. McKay; William G. Willmore; Maria C. DeRosa; David Sabatino
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Synthesis and pharmacological evaluation of a series of fluoro-substituted 3-phenoxy-azetidines as cortical enhancers for the treatment of apathy
delete2026-09-30
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PREAI
deleteClas Sonesson; Sverker von Unge; Maria Gullme; Li Rousk; Anne Fagerberg; Therése Knubbe; Boel Svanberg; Elisabeth Ljung; Angelica Johansson; Stephan Hjorth
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Design, synthesis and biological evaluation of novel CDK8/BRD4 dual inhibitors
delete2026-09-29
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PREAI
deleteLiang, Guoao; Zhang, Xiaochu; Zhu, Jiayi; Wang, Xinren; Huang, Jianhang
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Discovery of potent GPR120 activators with fatty orosensation enhancement activity
delete2026-09-28
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PREAI
deleteYayoi Kawato; Kazuhiro Sakamoto; Kotoe Nakasha; Seiichi Sato
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Discovery of Fisetin as a potent and cell-active ACVR2A inhibitor
delete2026-09-27
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PREAI
deleteXiaohan Bu; Mengzhe Dai; Zhen Fang; Jun Zou; Shengyong Yang
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Structure-activity profiling of indazole-based derivatives as spinster homolog 2 (Spns2)-dependent S1P release inhibitors
delete2026-09-26
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PREAI
deleteMario Hernandez; Deija J. Hawkins; Yugesh Kharel; Tao Huang; Audrey D. Prendergast; Anne M. Brown; Kevin R. Lynch; Webster L. Santos
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Synthesis and discovery of polyisopentenylated acylphloroglucinols with selective antiproliferative activity against breast cancer cells
delete2026-09-26
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PREAI
deleteHong-Yuan Wang; Yong Li; Jie Wei; Hong-Yan Han; Chen Yang; Li-Dong Shao; Xing-Ren Li; Gang Xu
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Photocaging of a GPR52 agonist enables light-dependent receptor activation in cells
delete2026-09-24
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deleteWen Ren; Yuexin Liu; Xiaoyan Dai; Qi Wang; Bo Zhang; Bichu Cheng
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The antiproliferative and pro-apoptotic effects of 3-deoxy-3α-fluoro-chenodeoxycholic acid and 12β-methyl-3,7-dioxo-17-epi-25-homo-18-nor-5β-cholan-25-oic acid on human breast cancer cell lines
delete2026-09-19
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deleteDivyashree Ravishankar; Joseph M. Watts; Andreas Luxenburger; Lawrence D. Harris; Wanting Jiao; Thibaut Dispa; Alex Weymouth-Wilson; Richard H. Furneaux; Bruno Linclau; Francesca Greco; Helen M.I. Osborn
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Discovery of potent, selective, and orally bioavailable monocyclic pyridine-based PKMYT1 inhibitors that synergize with CHK1 inhibition in replication-stressed cancer cells
delete2026-09-17
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deleteYing Sun; Hongzhu Chu; Yonggang Wei; Xinying Qian; Fei Ye; Hongchuan Zhao; Xinying Zhu; Jing Zhang; Song Huang; Mingyou Hu
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Quinolin(on)es and pyridin(on)es as promising scaffolds against mycobacterial infections
delete2026-09-16
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deleteMarie Gréverie; Alexandra Dassonville-Klimpt; Morgane Choquet; Claire Andréjak; Pascal Sonnet
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Electrophilic aromatic halogenation of perylenequinones: a strategy to improve photodynamic properties
delete2026-09-15
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deleteReema A. Al-Qiam; Ge Shi; Cedric J. Pearce; Lina Mardiana; Alexandra Longcake; Michael J. Hall; Michael R. Probert; Sherri A. McFarland; Shabnam Hematian; Nicholas H. Oberlies
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Amyloid-β aggregation inhibitory activity and neuroprotective effects of metabolites of Trichoderma pluripenicillatum
delete2026-09-15
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PREAI
deleteHayato Yoshikawa; Takahiro Matsumoto; Emi Yoshida; Tomoe Ohta; Tatsusada Yoshida; Yoshiki Noda; Shun Shimohama; Kazuyuki Takata
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Discovery of novel dual STAT3/TrxR1 inhibitors via pharmacophore fusion as potent lead compounds for colorectal cancer
delete2026-09-10
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PREAI
deleteYigui Li; Rui Xu; Xinhua Xie; Wanzhu Zhao; Linchong He; Tao Zheng; Wuyi Zhang; Pinghua Sun; Jun Xu; Xin Chen
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Synthesis and antimalarial activity of novel C30-aminated betulin derivatives
delete2026-09-01
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deleteBerube, Christopher; Bergeron, Catherine; Gagnon, Dominic; Gagne-Boulet, Mathieu; Fortin, Sebastien; Cote, Simon; Albericio, Fernando; Richard, Dave; Biron, Eric
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