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Acta Pharmaceutica Sinica B cover

Acta Pharmaceutica Sinica B

IF14.6
Papers2899
Citations26773
Journal Papers 2899
Publication Date
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An endo-[4+2] sesquiterpenoid dimer Jap-G targets USP5 for autophagosomal–lysosomal degradation to promote mutant P53 proteasomal degradation in triple-negative breast cancer
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-12
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deleteCong Guo; Xia Teng; Pengxiao Li; Xutong Fang; Junjie Yan; Wenwu Liu; Yiyu Qi; Rui Wang; Limin Zou; Jinming Gao; Xiaocong Pang; Jiangjiang Tang
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In vivo programming of CAR-T cells for solid tumors: Delivery platforms, local biomaterial strategies, and translational design
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-12
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deleteJing Zhang; Xinyu Lu; Xinyi Lu; Sitong Li; Ran Luo; Zhenyu Lu; Fan Zhang; Guihong Lu; Jinxie Zhang; Lin Mei
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The pathological mechanisms, mediators, and therapeutic strategies for cancer-related fatigue
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-10
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deleteHui Xu; Hua-Jun Wang; Nan Ru; Yi-Fang Li; Lei Liang; Cheng Yuan; Wen-Dong Xu; Xiao-Fei Zheng; Ju-Yan Liu; Yan-Ping Wu; Rong-Rong He
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CLCC1 gates endoplasmic reticulum-to-mitochondria calcium redistribution to restrain drug-induced liver injury
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-10
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deleteJie Jiang; Yi Wang; Rong Yang; Ying Hong; Xinyao Chen; Yameng Liu; Jingyi Xu; Jiaqi Li; Jingjie Zhao; Bingqing Xia; Zhaobing Gao; Weiwei Liu; Cen Xie
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Glycine at the crossroads: Significance in cardiovascular disease and metabolic health
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-09
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deleteYajia Ding; Yuting Liu; Yan Che; Qizhu Tang
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Advances in natural product-based radiopharmaceuticals
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-09
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deleteXimiao Yang; Quan Zuo; Dengfu Wu; Qimanguli Saiding; Hao Tian; Hongyi Huang; Quanshu He; Zirui Zhang; Junlong Lu; Jie Yan; Zihan Huang; Wei Tao; Rui Wang; Kuan Hu
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A multifunctional anti-influenza peptide targeting viral fusion and nucleoprotein
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-07
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deleteXiankun Wang; Jilong Shi; Jun Shu; Xuanyu Nan; Shaozhen Jiang; Chuyuan Zhang; Yao Chen; Zhifeng Guan; Pok Man Lai; Kong Hung Sze; Youhua Xie; Kelvin Kai Wang To; Kwok Yung Yuen; Yuhe Renee Yang; Hanjun Zhao
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Residual cardiovascular risk beyond LDL-C in ASCVD: Biological drivers, biomarkers, and therapeutic strategies
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-07
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deleteKe Gong; Junming Tang; Viktoria Stanislavovna Berestovskaya; Teppo Heimo; Hao Wang; Hui Huang; Yajun Duan
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Durability in nucleic acid therapeutics: Delivery barriers, immune constraints, and biological adaptation
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-07
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deleteAbid Naeem; Shuai Guo; Yuanyu Huang
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Rational design of novel macrocyclic peptide PET tracers targeting urokinase-type plasminogen activator receptor
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-06
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deleteSuyun Pu; Jiale Xie; Chuan Chen; Wenhao Liu; Jie Wang; Weiyan Li; Kezhi Ding; Yabin Yang; Jiawen Huang; Ding Lin; Jian Gao; Zonghua Luo
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Herpes simplex virus-1 activates MAPK signaling to destabilize the glycocalyx and enhance viral dissemination, underscoring risks in oncolytic applications
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-06
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deleteDivya Kapoor; Pankaj Sharma; Mannat Singh; Pradnya Sonawane; Sudhanshu Kumar Singh; Deepak Shukla
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Reprogramming macrophages and inducing trained immunity via a Mincle-engaging liposomal platform for antitumor therapy
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-06
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deleteConglin Chen; Xue Chen; Ruilian Yu; Tao Gong; Zhirong Zhang; Renhe Liu; Yao Fu
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A new PDGFRβ inhibitor ameliorates pulmonary hypertension via improving metabolic functions with reduced inflammatory environments
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-06
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deleteYihan Zhang; Shang Li; Tengge Lu; Lisha Ye; Mingxuan Wang; Jiangshan Guo; Lei Ye; He Zhu; Yongyi Bai; Baolian Wang; Yajun Yang; Tiantai Zhang; Lan Sun
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Unveiling distinct failure mechanisms of enteric coatings via time-lapse macro-imaging and large language model-based image analysis
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-11-06
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deleteShiyu Yi; Hongyi Yang; Xueling Li; Yixiang Yang; Xuan Gao; Li Deng; Yao Fu
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Deuteration leads to a broad-spectrum coronavirus main protease inhibitor with improved pharmacokinetic properties and potent in vivo efficacy
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-10-28
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deleteYejin Jang; Letian Song; Myoung Kyu Lee; Xiaoyi Hu; Katharina Sylvester; Chun-Chiao Yang; Byungil Kim; Linan Wu; Bing Ye; Xianghan Bai; Norbert Sträter; Christa E. Müller; Xinyong Liu; Meehyein Kim; Peng Zhan; Shenghua Gao
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Mitochondria-targeted sertraline (Mito-Sert) suppresses non-small cell lung cancer through VDAC1-mediated excessive mitophagy
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-10-27
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deleteJingbo Qin; Xiaohui Chen; Hongtao Chen; Luting Li; Zihao Teng; Nan Li; Yuchen Guo; Yongzhen Xia; Jiyun Liu; Hongying He; Guanmin Jiang; Xiaokun Zhang; Shuaidong Huo
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Targeting LXRα-R305 covalent activation for renal copper homeostasis restoration by natural pestaphilone A as an anti-AKI candidate
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-10-24
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deleteJianglian She; Huanguo Jiang; Tanwei Gu; Yi Chen; Jian Cai; Chuanliang Wei; Xi Zhang; Lingmin Tian; Wenxun Lan; Xin Qi; Fang Wu; Hao Zhang; Yuanxin Tian; Yonghong Liu; Wei Xu; Lan Tang; Xuefeng Zhou
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Structural insights into orthosteric and allosteric inhibition of non-canonical oncogenic PI3Kα mutants
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-10-24
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deleteAnqi Chen; Guanyi Li; Xiao Liu; Yue Qiu; Fangqing Zhao; Yanyan Chen; Yi Wang; Mingcong Lv; Pengrui Qu; Jian Ding; Linghua Meng; Qingtong Zhou; Ming-Wei Wang
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ACOD1 facilitates Staphylococcus aureus-induced training of macrophages to protect against asthma via promoting efferocytosis
deleteActa Pharmaceutica Sinica B
IF14.6
delete2026-10-24
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deleteXinyi Yang; Wen Li; Huixing Li; Yusen Gou; Honglin Xu; Yaoshuai Zhang; Buyong Ma; Haibo Zhang; Feng Qian; Lei Sun
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A first-in-class methuosis inducer targeting Nur77/LYSET axis for the treatment of non-small cell lung cancer, irrespective of cisplatin resistance
deleteActa Pharmaceutica Sinica B
IF14.6
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deleteJun Chen; Jingbo Qin; Wenbin Hong; Xiaodan Li; Taige Zhao; Xiaohui Chen; Yuxuan Huang; Shengwei Hu; Xuan Hou; Weihao Liu; Jun Wu; Hongsheng Li; Wanhao Wen; Tianwei Lin; Zhen Wu; Baicun Li; Yingkun Qiu; Xueqin Chen; Meijuan Fang
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