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RSC Medicinal Chemistry cover

RSC Medicinal Chemistry

IF3.6
Papers1342
Citations2906
Journal Papers 1326
Publication Date
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Integrated platform for accelerating therapeutic macrocyclic peptide purification in high-throughput medicinal chemistry
deleteRSC Medicinal Chemistry
IF3.6
delete2026-08-19
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PREAI
deleteJun Wang; Faben Cruz; Lingfei Wang; Angel Ho; May Kong; Michael Hayes; Thomas J. Greshock; Kanaka Hettiarachchi Corresponding Author
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Research progress regarding iminosugars for glycosidase inhibition and hypoglycemic activity
deleteRSC Medicinal Chemistry
IF3.6
delete2026-08-19
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deleteChao-Na An; Mei-Qi Yang; Xin-Ran Song; Hai-Shan Zhao; Fangqian Yin; Meng-Yue Li; Ke-Rang Wang Corresponding Author
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Drug repurposing of fluvastatin as a DP2 antagonist: an ensemble learning strategy with in vitro cellular functional validation
deleteRSC Medicinal Chemistry
IF3.6
delete2026-08-19
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deleteGuoHui Wei Corresponding Author; Zhuo Sun; YuanXu Gao; Jia Heng; WenYang Lu; ZiXing Zou
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Probing pyrazolo-pyrimidines as SIRT2 inhibitors via molecular modelling and biological assays
deleteRSC Medicinal Chemistry
IF3.6
delete2026-08-19
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PREAI
deleteFrancesca Musumeci; Cecilia Astigiano; Naomi Scarano; Marta Falesiedi; Giorgia Guccione; Jade Calamano; Annalisa Salis; Caterina Miro; Chiara Brullo; Monica Dentice; Elena Cichero Corresponding Author; Santina Bruzzone; Silvia Schenone
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Design; synthesis; and X-ray structural studies of potent SARS-CoV-2 Mpro inhibitors containing tetrahydroisoquinoline-3-carboxamides as P2 ligands
deleteRSC Medicinal Chemistry
IF3.6
delete2026-07-24
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deleteArun K. Ghosh Corresponding Author; Ashish Sharma; Satyanarayana Iddum; Sydney N. Bogan; Uttara Jayashankar; Emma K. Lendy; Shin-ichiro Hattori; Nobuyo Higashi-Kuwata; Hiroaki Mitsuya; Andrew D. Mesecar
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Structure–activity relationship for calanthoside; a potential hair-growth stimulant with an indole 2-S-; 3-O-bis-glucoside structure. Part 1: role of two glucoside moieties in promoting HFDPC proliferation
deleteRSC Medicinal Chemistry
IF3.6
delete2026-07-24
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PREAI
deleteRiko Suzuki; Katsuki Takashima; Yoshiaki Manse; Haruto Nishikawa; Mina Ashidate; Shinsuke Marumoto; Fumihiro Ishikawa; Toshio Morikawa Corresponding Author; Genzoh Tanabe Corresponding Author
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Ruthenium(ii) polypyridyl complexes and the DNA damage response: mechanisms and therapeutic implications
deleteRSC Medicinal Chemistry
IF3.6
delete2026-05-01
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deleteGill, Martin R.
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Diverse ring architectures of cyclic peptidomimetics targeting melanocortin receptors
deleteRSC Medicinal Chemistry
IF3.6
delete2026-04-01
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PREAI
deleteYue, Wenxiao K.; Barlow, Nicholas; Thompson, Philip E.
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Lead optimization of 5jc21 (CG13250), a quinolin-2(1H)-one-based inhibitor of the BRD4 member of the bromodomain and extraterminal (BET) family of proteins
deleteRSC Medicinal Chemistry
IF3.6
delete2026-04-01
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PREAI
deleteChauhan, Jay; Pogash, Sarah; Yoshioka, Makoto; Raje, Mithun; Van Eker, Daniel; Strovel, Jeffrey W.; Fletcher, Steven
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Design, synthesis and biological evaluation of benzoyl hydrazone derivatives as anticancer agents inducing ROS-associated mitochondrial apoptosis
deleteRSC Medicinal Chemistry
IF3.6
delete2026-03-01
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deleteWei, Rongbin; Wang, Xin; Ding, Yamin; Zhu, Suting; Asiedu, Richmond Kwame Frimpong; Li, Muzi; Qian, Haitao; Gu, Yifei; Jiang, Bailing
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d-Galactose-conjugated pyrimidine thioureas as potent antimicrobial agents: rapid green synthesis, structure-activity relationships and molecular modelling
deleteRSC Medicinal Chemistry
IF3.6
delete2026-03-01
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PREAI
deleteThanh, Nguyen Dinh; Toan, Vu Ngoc; Thu, Ngo Hong Anh; Tri, Nguyen Minh; Toan, Duong Ngoc; Van, Hoang Thi Kim
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The effects of bioisostere substitution on the antimicrobial and physicochemical properties of supramolecular self-associating amphiphiles
deleteRSC Medicinal Chemistry
IF3.6
delete2026-03-01
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deleteNaicker, Pinky K.; Yacoub, Mariam; White, Lisa J.; Balderston, Dominick E.; Hailey, Perry A.; Sutton, J. Mark; Hind, Charlotte K.; Hiscock, Jennifer R.
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The dual functions of a nor-sesquiterpene-triazole derivative against influenza A viruses through the activation of the Nrf2/HO-1 signaling pathway and interaction with hemagglutinin
deleteRSC Medicinal Chemistry
IF3.6
delete2026-02-01
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PREAI
deleteZhou, Shaofen; Wei, Jingyan; Li, Shixin; Qiu, Jingnan; Ma, Shuaiqi; He, Jian
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PROTAC-mediated multi-target protein degradation in Alzheimer's disease: mechanistic insights, therapeutic applications, and translational challenges
deleteRSC Medicinal Chemistry
IF3.6
delete2026-02-01
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deleteWang, Bin; Li, Yunan; Yao, Tingting; Shen, Xinai; Li, Huan; Jiang, Wei; Li, Xinuo; Zhu, Zheying
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, a novel DYRK1A inhibitor, attenuates neuroinflammation and cognitive impairments in LPS-induced mice: a potential strategy for Alzheimer's disease
deleteRSC Medicinal Chemistry
IF3.6
delete2026-02-01
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deleteRen, Mengyu; Chen, Huanhua; Li, Zhenshu; Zhuang, Jiacheng; Yang, Aizhu; Li, Xiangdong; Li, Xinyu; Wang, Xinpeng; Xu, Zonghe; Liu, Xianghuan; Song, Jiawen; Jiang, Tianhao; Xu, Zihua; Gao, Xudong; Zhao, Qingchun
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Integrating green synthesis and liquid-liquid extraction of lidocaine in deep eutectic solvents
deleteRSC Medicinal Chemistry
IF3.6
delete2026-02-01
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deletePerri, Assunta; Parrotta, Leonardo C.; Gencarelli, Stefania; Sole, Roberta; Dragostin, Oana M.; Guillena, Gabriela; Di Gioia, Maria L.
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Adamantane-based inhibitors of the influenza A M2 proton channel: structure-based design, biological evaluation, and synthetic approaches
deleteRSC Medicinal Chemistry
IF3.6
delete2026-02-01
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deleteStampolaki, Marianna; Kouridaki, Maria-Eleni; Georgiou, Kyriakos; Kolocouris, Antonios
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Empowering molecular complexity via biocatalysis: emerging blueprints in the total synthesis of medicinally relevant natural products
deleteRSC Medicinal Chemistry
IF3.6
delete2026-02-01
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deleteYadav, Ram N.; Dey, Sovan; Hossain, Md. Firoj; Ray, Devalina; Banik, Bimal K.; Schmidt, Luciana C.; Singh, Vandana
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Theranostic advances in Alzheimer's disease: structure-guided design of near-infrared fluorescent probes targeting amyloid-β and cholinergic dysfunction
deleteRSC MEDICINAL CHEMISTRY
IF3.6
delete2026-01-01
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deleteMandloi, Upesh; Giri, Namita; Kumar, Saroj; Modi, Gyan
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Design, synthesis, and structural elucidation of ethyl 2-amino-5-oxo-4-aryl-4H-pyrano[3,2-c]quinoline-3-carboxylates as dual EGFR/HER-2 inhibitors endowed with antiproliferative activity
deleteRSC MEDICINAL CHEMISTRY
IF3.6
delete2025-12-01
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deleteAl-Wahaibi, Lamya H.; Abou-Zied, Hesham A.; Mohassab, Aliaa M.; Fathy, Hazem M.; Alzahrani, Abdullah Yahya Abdullah; Youssif, Bahaa G. M.
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