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Nucleic Acid Therapeutics cover

Nucleic Acid Therapeutics

IF4.7
Papers603
Citations1694
Journal Papers 775
Publication Date
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Applying Synthetic Nucleic Acid Therapeutics to Gene Activation for Haploinsufficient Diseases
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-12-01
delete0
PREAI
deleteTse, Victor; Corey, David R.
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An RNA Aptamer Targeting PAI-1 That Restores tPA Activity, Unexpectedly Suppresses Cancer Cell Progression
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-12-01
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PREAI
deleteHu, Christopher; Schneidler, Austin; Barry, Mamadou; Gimba, Michelle; Zhou, Sihan; Fortenberry, Yolanda M.
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Letter: Correspondence on Damle, SS, et al. (2025) A Workflow for Transcriptome-Wide Assessment of Antisense Oligonucleotide Selectivity. Nucleic Acid Therapeutics
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-12-01
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PREAI
deleteCrooke, Stanley T.
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Immunogenicity Risk Assessment for Nucleic Acid Therapeutics: A Comprehensive Evaluation for ASO; siRNA; and Nonvaccine mRNA/LNP Therapies by the IQ Consortium
deletenucleic acid therapeutics
IF4.7
delete2025-11-05
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PREAI
deleteJoanna Grudzinska-Goebel; Manuela Braun; Lin-Zhi Chen; Swati Gupta; Sabine Lohmann; Pedro Morais; Tao Niu; Edit Tarcsa; Sophie Tourdot; Amir S. Youssef; Vibha Jawa
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Unveiling Liver Micro-Distribution: NanoSIMS Imaging Reveals Critical Intracellular Distribution of Chemically Modified Antisense Oligonucleotides
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-11-01
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PREAI
deleteYasuhara, Hidenori; Kadotsuji, Kenta; Watanabe, Kenichi; Kakutani, Tomomi; Tochitani, Tomoaki; Mise, Izuru; Konishi, Mei; Nakagawa, Tetsuya; Miyawaki, Izuru
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Antisense Oligonucleotide Quantification via Splint-Ligation PCR Assay in Nonhuman Primate Central Nervous System Tissues and Biofluids
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-11-01
delete0
PREAI
deleteJepp, Thomas; Christian, Sarah; Dindot, Scott V.
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Class-Specific Adverse Events of Patients Treated with Small Interfering RNA Therapeutics: A Disproportionality Analysis of the United States Food and Drug Administration Adverse Event Reporting System Database Based on the MY FAERS Platform
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-11-01
delete0
PREAI
deleteLi, Ze; Wang, Xiaozhen; Li, Dandan; Sun, Yiqi; Zhang, Lin; Li, Xingang
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A Workflow for Transcriptome-Wide Assessment of Antisense Oligonucleotide Selectivity
deletenucleic acid therapeutics
IF4.7
delete2025-09-29
delete0
PREAI
deleteSagar S. Damle; Andy Watt; Steven Kuntz; Amanda Crutchfield; Emma Carlborg; Judy Webb; Clare Quirk; Dorde Relic; Scott Donovan; Christopher E. Hart; Frank Rigo
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Cryopreservation of siRNA-Treated Cells Is Feasible
deletenucleic acid therapeutics
IF4.7
delete2025-09-23
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deleteOAAI
deleteMelanie Sauer; Xavier Segarra-Visent; Leon Breuer; Vasileios Tzirtziganis; Tatyana Ryaykenen; David A. Cooper; Dimas Echeverria; Anastasia Kremer; Reka A. Haraszti
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Use of a Transgenic Human PNPLA3I148M Knock-in Mouse for Translational Safety Evaluations of siRNA Therapeutics
deletenucleic acid therapeutics
IF4.7
delete2025-09-06
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PREAI
deleteBen Brooks; Artem Shkumatov; Jackson Kalanzi; Kim Henderson Park; Julie M. Lade; Diana Wong; Hui Dou; Jason Long; Ingrid C. Rulifson; Justin K. Murray; Lauren Mihalcik; Tod A. Harper
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Binding and Ligand Activation Driven Enrichment-Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-09-01
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PREAI
deleteLlanga, Telmo; Bush, Korie; Sun, Ying; Yan, Amy; Zhou, Jonathan; Gorodkin, Jan; Sullenger, Bruce A.
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Quantification of mRNA Decay Rates in HeLa and SH-SY5Y Cell Lines Reveals Novel Properties of Membrane Protein Coding Transcripts
deleteNUCLEIC ACID THERAPEUTICS
IF4.7
delete2025-09-01
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PREAI
deleteMartinez, Melanie B.; Williamson, Colton J.; Cazares, Tareian; Tang, Chunlao; Debets, Marjoke F.; Gangras, Pooja
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In Vivo Phage Display for the Identification of Muscle Homing Peptides to Improve the Delivery of Phosphorodiamidate Morpholino Oligomers for Duchenne Muscular Dystrophy Therapy
deletenucleic acid therapeutics
IF4.7
delete2025-08-29
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PREAI
deleteAnne-Fleur E. Schneider; Christa L. Tanganyika-de Winter; Hailiang Mei; Silvana M. G. Jirka; Xuyu Tan; Emily G. Thompson; Kristin Ha; Anindita Mitra; Stephanie Garcia; Marleen Luimes; Ryan Oliver; Kathy Y. Morgan; Vincent Guerlavais; Annemieke Aartsma-Rus
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Cell Type Distribution of Intrathecal Antisense Oligonucleotide Activity in Deep Brain Regions of Non-Human Primates
deletenucleic acid therapeutics
IF4.7
delete2025-08-26
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deleteJeannine A. Frei; Juliana E. Gentile; Yuan Lian; Meredith A. Mortberg; Juliana Capitanio; Paymaan Jafar-nejad; Sonia M. Vallabh; Hien T. Zhao; Eric Vallabh Minikel
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Context Matters: The Importance of a Comprehensive Genomic Region When Assessing the Therapeutic Potential of Antisense Oligonucleotides in Splicing Assays
deletenucleic acid therapeutics
IF4.7
delete2025-08-25
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PREAI
deleteDyah W. Karjosukarso; Julia F. Kiefmann; Femke Bukkems; Lonneke Duijkers; Rob W.J. Collin
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Rosalind Franklin Society Proudly Announces the 2024 Award Recipient for Nucleic Acid Therapeutics
deletenucleic acid therapeutics
IF4.7
delete2025-08-07
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PREAI
deleteAurélie Goyenvalle
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Characterizing Antibodies Targeting Antisense Oligonucleotide Phosphorothioate and 2′-O-Methoxyethyl Modifications for Intracellular Trafficking and Biodistribution Studies
deletenucleic acid therapeutics
IF4.7
delete2025-07-21
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PREAI
deleteInês Fial; Seth A. Farrier; David P. Chimento; Carl A. Ascoli; Xiao Wan; Peter L. Oliver
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Molecular Modeling of Antisense Oligonucleotide Analogs
deletenucleic acid therapeutics
IF4.7
delete2025-07-03
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PREAI
deleteRodrigo Galindo-Murillo
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Exosome-Mediated Mitochondrial Delivery of Antisense Oligonucleotides
deletenucleic acid therapeutics
IF4.7
delete2025-06-18
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PREAI
deleteDora von Trentini; Ivan J. Dmochowski
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Developmental and Reproductive Toxicity Testing Strategies for Oligonucleotides: A Workshop Proceedings
deletenucleic acid therapeutics
IF4.7
delete2025-06-05
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PREAI
deleteBethany R. Hannas; Sara M. Bender; Eileen Blasi; Christopher J. Bowman; Joy A. Cavagnaro; Connie L. Chen; Pragati S. Coder; Britt Duijndam; Alan Hoberman; Tae-Won Kim; Isabelle Leconte; Kazushige Maki; Mineo Matsumoto; Fumito Mikashima; Dinah L. Misner; Lutz Mueller; Nicola Powles-Glover; Stephanie Rayhon; Camelia Saffarini; Christine Siezen; Jennifer Sisler; Ronald L. Wange; Tacey White; Michael V. Templin
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