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Molecular Therapy cover

Molecular Therapy

IF12
Papers9898
Citations29788
Journal Papers 25361
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An unexpected role of the transgene in saRNA replication
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IF12
delete2026-08-12
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deleteChristin Schmidt; Tim Beissert
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Lipid Nanoparticles Based Multi-Scale Systemic Immune Programming for Cancer Therapy
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delete2026-08-10
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deleteXinwen Lin; Yong Li; Xiling Shen; Bowen Li; Yue Xu
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Human iPSC-derived neural progenitor gene therapy improves outcomes in a neuropathic lysosomal disease
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delete2026-08-10
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deleteOriana Mandolfo; Yuko Ishikawa Learmonth; Asma’u Usman; Maryann Lorino; Tereza Andreou; Rebecca Holley; Bei Qiu; Tristan Mckay; Brian Bigger
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Integrin α7 Defines a Profibrotic and Proinflammatory Adipose Stromal Population Targeted for Nanoparticle PAI-1 Gene Silencing in Obesity
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delete2026-08-10
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deleteLinda Mota; David Zhang; Yulieth Soto Ortiz; Federico Zertuche Gonzalez; Eunhee Chung; Caleb Dang; Achraf Noureddine; Eric M. Brey; Maria A. Gonzalez Porras
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Accelerated design of antiviral peptides to clamp down on emerging pathogens
deleteMolecular Therapy
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delete2026-07-31
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deleteKatherine A. Fitzgerald; Terence R. Flotte
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Tissue-Specific Silencing of Synthetic mRNAs By De-Targeting Elements Maps Vaccination-Competent Tissues, and Allows Cas9 De-Immunization
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IF12
delete2026-07-29
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deleteGuendalina Froechlich; Annagiulia Scognamiglio; Simone Totaro; Linda Nocchi; Emilio Pellino; Andrea Campanile; Luigia Infante; Giulio Miano; Alessandra Centore; Francesco Molfetta; Alessandra Napolano; Anna Morena D’Alise; Silvia Parisi; Alfredo Nicosia; Emanuele Sasso; Nicola Zambrano
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Development of Recombinant Anti-TLR2 Antibodies and PLGA Nanoparticle-Based Gene Therapy for the Treatment of Neuropathic Pain
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delete2026-07-29
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deleteSubeen Lee; Jaekyung Jeon; Hyunji Lee; Ellane Eda Barcelon; Jinpyo Hong; Sung Joong Lee
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A Helicase-Fused Cas9 improves Large-Size Fragment Knock-in
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IF12
delete2026-07-29
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deleteDuowei Zhao; Xiangjie Zhao; Yuhang Gao; Sujie Yang; Xiaochen Guo; Caiyan Zhang; Chuanpei Li; Chengda Zhang; Huan Tian; Qianqian Xu; Zhi Yin; Zhonghua Liu; Jun Song
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Capless self-amplifying mRNA vaccine induces dose-sparing protective immunity against HPAI clade 2.3.4.4 H5 virus in mice
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IF12
delete2026-07-29
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deleteBeom Kyu Kim; Ji-Hyun Park; Won-Suk Choi; Sol Oh; Se Hee An; Gi Chan Lee; Santosh Chokkakula; Chang-Ung Kim; Ju Hwan Jeong; Seong Cheol Min; Dong Gyu Lee; Ju Ryeong Lee; Sun-Woo Yoon; Doo-Jin Kim; Timothy J. Mahony; Richard J. Webby; Young Ki Choi; Yun Hee Baek; Min-Suk Song
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Dysregulated Proline Metabolism Contributes to Retinal Fibrosis in Neovascular AMD: Therapeutic Potential of Prolyl-4-Hydroxylase Inhibition
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delete2026-07-29
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deleteYue Zeng; Ting Zhang; Elisa Cornish; So-Ra Lee; Michelle Yam; Mark Eminhizer; Jingwen Zeng; Jialing Zhang; Shaoxue Zeng; Azhar Dzulhadj B. Arafah; Xian Wei; Jinliang Yang; Meidong Zhu; Andrew Chang; Meixia Zhang; Jianhai Du; Ling Zhu; Mark C. Gillies
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Synchronized Latency Reversal and Immune Clearance by a Multifunctional Fusion Protein Enables HIV-1 Reservoir Reduction
deleteMolecular Therapy
IF12
delete2026-07-29
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deleteFei Luo; Yinghui Cao; Na Liu; Xiaowei Wang; Wenjia Hu; Yajun Yan; Xiaoqing Xie; Dongmei Jiang; Yangyang Xu; Jun Wang; Hongyu Wang; Zhenyang Yu; Peng Qian; Shicheng Wan; Zhida Liu; Yan Gong; Tielong Chen; Shihui Song; Yong Xiong; Xiaoping Tang
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Prothrombin recognition and conformational modulation by anti-thrombin anticoagulant aptamers
deleteMolecular Therapy
IF12
delete2026-07-24
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deleteRomualdo Troisi; Alessandro Cangiano; Nathan Cowieson; Vera Spiridonova; Nicola Pozzi; Pompea Del Vecchio; Luigi Paduano; Filomena Sica
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Neuritin’s potential as a new therapeutic target for diverse autoimmune diseases
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IF12
delete2026-07-24
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deleteWen Zeng; Di Yu; Pablo F. Canete
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Evaluating cases of possible insertional mutagenesis after AAV gene therapy
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IF12
delete2026-07-23
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deleteLindsey A. George; Rebecca C. Ahrens-Nicklas; Frederic D. Bushman
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Identification of AAV Vector Integration Sites in Primary Human and Macaque Hepatocytes in vivo, and Analysis of Oncogenic Risk
deleteMolecular Therapy
IF12
delete2026-07-22
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deleteSuzanne Scott; Claus V. Hallwirth; Natsuki Sasaki; Sharon C. Cunningham; Erhua Zhu; Neeta Khandekar; Eddy Kizana; Julien Baruteau; Paul Gissen; Dany P. Perocheau; Denis C. Bauer; Laurence O.W. Wilson; Leszek Lisowski; Ian E. Alexander
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The dermis as a gene therapy target: AAVrh32.33 finds an unexpected home in skin
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delete2026-07-22
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deleteEline S. Herman; Irina Filz von Reiterdank
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Industrial translation of AI-driven nucleic acid therapies
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delete2026-07-21
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deleteZhongkun Zhang; Siyu Yao; Ethan Loo; Naveen Reddy; Mansoor Amiji
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Nicotinamide riboside tunes adoptive T cells for memory and metabolic fitness
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delete2026-07-21
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deleteZhenyu Dai
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FGF21 gene therapy for healthy aging: Great promise, important questions
deleteMolecular Therapy
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delete2026-07-21
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deleteMakoto Kuro-o
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The power of one: The unexpected benefits of correcting a single tissue in multisystem mitochondrial disease
deleteMolecular Therapy
IF12
delete2026-07-20
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deleteCarlos T. Moraes
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