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CPT-Pharmacometrics and Systems Pharmacology

IF3
Papers1076
Citations4051
Journal Papers 1071
Publication Date
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Response to “Enhance Multistate Models With Clinically Meaningful Graphs”
deletecpt pharmacometrics systems pharmacology
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delete2025-09-05
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deleteMoustafa M. A. Ibrahim; Maria C. Kjellsson; Mats O. Karlsson
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Enhance Multistate Models With Clinically Meaningful Graphs
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delete2025-09-05
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deleteJoachim Grevel
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Rosuvastatin PBPK Modeling: Incorporating Liver Concentrations and Effects of Ethnicity, Genetic Polymorphisms, Lactone Formation, DDI and Pregnancy
deletecpt pharmacometrics systems pharmacology
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delete2025-08-25
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deleteAnkit Balhara; Robert H. Weber; Jashvant D. Unadkat
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Model-Informed Drug Development for Ligelizumab in Patients With Chronic Spontaneous Urticaria
deletecpt pharmacometrics systems pharmacology
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delete2025-08-23
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deleteAndrzej Bienczak; Aurelie Gautier; Eva Hua; Yan Ji; Emil Scosyrev; Serge Smeets; Thomas Severin; Anton Drollmann; Manmath Patekar; Marina Savelieva
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Population Pharmacokinetic Model of Pegbing in Healthy Subjects and Chronic Hepatitis B Patients
deletecpt pharmacometrics systems pharmacology
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delete2025-08-21
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deleteWeizhe Jian; Yalin Yin; Rong Chen; Pingyao Luo; Tianyu Wang; Jianbo Gu; Zhengfang Du; Lei Cai; Tianyu Bao; Junsheng Xue; Ruoyi He; Tianyan Zhou
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A Combined Modeling Approach to Predict the Effect of Gastric Emptying Delay on the Pharmacokinetics of Small Molecules
deletecpt pharmacometrics systems pharmacology
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delete2025-08-21
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deleteMaria M. Posada; Karen B. Schneck; Bridget L. Morse; Luc R. A. Rougee; Lai San Tham; Jessica F. Rehmel; Brian Thompson; Stephen D. Stamatis; Stephen D. Hall; Gemma L. Dickinson
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A Bayesian Approach to Compare Accumulating Survival Data From Clinical Practice With RCT Data: A Case Study in Non-Small Cell Lung Cancer Patients
deletecpt pharmacometrics systems pharmacology
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delete2025-08-21
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deleteMarjon V. Verschueren; Daniel V. Verschueren; Ewoudt M. W. van de Garde; Lourens T. Bloem
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Toward a Quantitative Understanding of Aficamten Clinical Pharmacology: Population Pharmacokinetic Modeling
deletecpt pharmacometrics systems pharmacology
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delete2025-08-17
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deleteDonghong Xu; Hanbin Li; Stephen B. Heitner; Daniel L. Jacoby; Stuart Kupfer; Polina German; Justin Lutz
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Exposure–Response Analysis of Repotrectinib to Support the Dose Recommendation for Patients With ROS1-Positive NSCLC or NTRK-Positive Solid Tumors
deletecpt pharmacometrics systems pharmacology
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delete2025-08-17
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deleteShengnan Du; Zheyi Hu; Jun Shen; Li Zhu; Amit Roy; Justine Lam; Ming Lu; Anna Kondic; Lora Hamuro
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Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases
deletecpt pharmacometrics systems pharmacology
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delete2025-08-13
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deleteAlex Foster-Powell; Amin Rostami-Hodjegan; Guy Meno-Tetang; Donald E. Mager; Kayode Ogungbenro
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A Perspective on the Use of Poisson Versus Logistic Regression in Exposure–Response Analysis: Insights and Considerations
deletecpt pharmacometrics systems pharmacology
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delete2025-08-12
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deleteYiming Cheng; Ping Chen; Yan Li
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A Systematic Comparative Analysis of Tumor Size Models Based on Erlotinib Clinical Data in Advanced NSCLC
deletecpt pharmacometrics systems pharmacology
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delete2025-08-11
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deleteAnna Mishina; Kirill Zhudenkov; Gabriel Helmlinger; Kirill Peskov
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Target-Mediated Drug Disposition Revisited: Michaelis–Menten Approximations for Bivalent Drug Molecules
deletecpt pharmacometrics systems pharmacology
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delete2025-08-08
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deleteRonny Straube
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A Case Study of Model-Informed Drug Development of a Novel PCSK9 Antisense Oligonucleotide. Part 2: Phase 2 to Phase 3
deletecpt pharmacometrics systems pharmacology
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delete2025-08-05
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deleteJane Knöchel; Catarina Nilsson; Björn Carlsson; Alexis Hofherr; Per Johanson; Tina Rydén-Bergsten; Bengt Hamrén; Dinko Rekić
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Predicting Systemic and Liver Bosentan Exposure Using Physiologically-Based Pharmacokinetic Modeling
deletecpt pharmacometrics systems pharmacology
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delete2025-08-05
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deleteMiao-Chan Huang; Julia Macente; Sofie Heylen; Chen Ning; Kristof De Vos; Neel Deferm; Pieter Annaert
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A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders
deletecpt pharmacometrics systems pharmacology
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delete2025-08-05
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deleteYevgen Ryeznik; Ralf-Dieter Hilgers; Nicole Heussen; Emmanuelle Comets; France Mentré; Niels Hendrickx; Mats O. Karlsson; Andrew C. Hooker; Alzahra Hamdan; Xiaomei Chen; Rebecca Schüle; Matthis Synofzik; Oleksandr Sverdlov
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Assessing Cytochrome P450 Drug Interaction Risk for Dordaviprone Using Physiologically Based Pharmacokinetic Modeling
deletecpt pharmacometrics systems pharmacology
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delete2025-08-04
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deleteSwati Jaiswal; Nikunjkumar K. Patel; Hannah M. Jones; Savannah McFeely; Shamia L. Faison; Tim Tippin; Odin Naderer
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Model-Informed Precision Dosing of Infliximab in Korean Inflammatory Bowel Disease Patients: External Validation of Population Pharmacokinetic Models
deletecpt pharmacometrics systems pharmacology
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delete2025-08-04
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deleteYoonjin Kim; Seung Hwan Baek; In-Jin Jang; Jae-Yong Chung
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Transforming Pediatric Rare Disease Drug Development: Enhancing Clinical Trials and Regulatory Evidence With Virtual Patients
deletecpt pharmacometrics systems pharmacology
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delete2025-08-04
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deleteFianne Sips; Marco Virgolin; Giuseppe Pasculli; Federico Reali; Alessio Paris; Annette Janus; Yann Godfrin; Daniel Röshammar; Luca Marchetti; Jane Knöchel
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Moving From Point-Based Analysis to Systems-Based Modeling: Knowledge Integration to Address Antimicrobial Resistance
deletecpt pharmacometrics systems pharmacology
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delete2025-08-01
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deleteBhavatharini Arun; Gauri G. Rao
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