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Drug Metabolism and Pharmacokinetics cover

Drug Metabolism and Pharmacokinetics

IF2.2
Papers103
Citations1944
Journal Papers 88
Publication Date
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Theoretical Analysis of Developmental Changes in Adenosine A2A Receptor Occupancy in Premature Infants Under Caffeine Therapy
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-10-09
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deleteOAAI
deleteHaruka Ide; Akane Hara; Ryosuke Fujihara; Kokoro Fukuzawa; Masato Taguchi
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Microsomal and Hepatocyte Binding in Drug Discovery: Method Suitability and Lipophilicity-Based Predictions
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-10-06
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PREAI
deleteLeonel Torrão; Gaëlle Chenal; Stephane Rodde; Birk Poller; Sujal V. Deshmukh; Julia Riede
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Evaluation of Food Effects on Oral Absorption from Lipid-Based Formulations Using an In Vitro Digestion–In Situ Absorption Model with a Physiologically Relevant Surface Area to Volume Ratio
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-10-03
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PREAI
deleteYusuke Tanaka; Shogo Sasaki; Hiroto Nishiura; Ko Imai; Haruya Yagi; Shinji Sakuma
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Translational limitations of a rat-derived hybrid pharmacokinetic–toxicodynamic model for chemotherapy-induced hematologic toxicity in humans
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-09-28
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PREAI
deleteShinji Kobuchi; Kenji Ikemura; Akihide Kobayashi; Masahiro Okuda; Yukako Ito
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Beyond Km and Vmax: a geometric framework for characterising enzyme modulation and validating kinetic data
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-09-28
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PREAI
deleteJonathan Salerno
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Assessment of Infliximab Biotransformation in Patient Serum by Comparing Mass-Spectrometry and Ligand-Binding Assay Quantification
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-09-15
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deleteSho Masui; Aoto Nakajima; Kodai Yajima; Takashi Shimada; Akira Onishi; Makoto Okabe; Shuji Yamamoto; Tomohiro Terada; Atsushi Yonezawa
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Characterization of unusual pyrazole ring-rearranged metabolites of DS-1971a specific to monkeys
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-08-01
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PREAI
deleteAsano, Daigo; Michiba, Kazuyoshi; Masuda, Kayoko; Ohnuki, Takashi; Suzuki, Makoto; Suzuki, Tetsuya; Shiozawa, Hideyuki; Shinozuka, Tsuyoshi; Takatsu, Toshio; Nakai, Daisuke
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Development of a Method for Vancomycin Monitoring in Interstitial Fluid Using a Novel Porous Microneedle Array Patch
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-06-30
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deleteJo Terauchi; Taisei Kawamura; Jongho Park; Kiyomi Saito; Masataka Tajima; Hitoshi Sato; Beomjoon Kim; Erika Sugiyama
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β-Cyclodextrin as a Negative Allosteric Modulator of Mammea A/AA Binding to Serum Albumin: A Spectroscopic and Molecular Dynamics Study
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-06-29
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PREAI
deleteAteba A. Baruch; Mathieu J.M. Tjegbe; Loveline T. Bamou; Hans M.T. Fofack; Maraf M. Bake; Luc M. Mbaze
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Development and validation of LC–MS-based bioanalytical methods for oligonucleotide therapeutics: points to consider
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-06-19
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PREAI
deleteYuchen Sun; Kosuke Saito; Shin-ichiro Nitta; Ryoya Goda; Yuki Kishino; Hisashi Fujita; Masaaki Kakehi; Yoshiharu Hayashi; Satoshi Ito; Tomomi Ishida; Kiyomi Kikuchi; Kazuko Inoue; Kazutaka Shimbo; Takeru Yamaguchi; Fumihiro Jinno; Kaori Murakoshi; Chie Murata; Kentaro Takahara; Mitsuhiko Kawabata; Ruri Kikura-Hanajiri
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A Permeability Assay Adapted for the Assessment of Very Poorly Permeable Compounds in the bRo5 Space.
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-06-02
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PREAI
deletePaulina Page; Dallas Bednarczyk
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Tyrosine kinase inhibitors suppress cytochrome P450 2C8 and 2J2 functions and their expression in renal cell carcinoma
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-05-29
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PREAI
deleteAyaka Kojima; Masayuki Nadai; Hiroshi Yamazaki; Miki Katoh
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A novel scaling approach for human pharmacokinetic prediction of antibody-drug conjugates using minimal nonclinical data: Integration of monkey PK and in vitro data
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-05-28
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PREAI
deleteSatoshi Nakayama; Nao Torimoto; Toshiyuki Kudo; Kiyomi Ito
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K2-EDTA Anticoagulant Suppresses Calcium-Dependent Paraoxonase 1-Mediated Hydrolysis in Human Plasma Stability Assays
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-21
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PREAI
deleteLloyd Wei Tat Tang
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Role of the arachnoid mater organic anion and cation transporters in the clearance of prostaglandin D2 and metformin from the cerebrospinal fluid in rats
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-17
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PREAI
deleteYuka Yaguchi; Kazunari Sasaki; Mai Inagaki; Tetsuya Terasaki; Masanori Tachikawa
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Differences in reactive metabolite formation and cytochrome P450 binding between acetaminophen and its bicyclo[1.1.1]pentane bioisostere
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-15
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PREAI
deleteMinami Shibata; Ayato Mizuno; Tomoki Nakayoshi; Akifumi Oda; Masaya Nakajima; Masanobu Uchiyama; Masahiro Hiratsuka; Yoshihiro Yamanishi; Kouichi Yoshinari
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Microfluidic post-insertion preparation and evaluation of RGD- and PEG-modified macrophage-derived small extracellular vesicles
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-02
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deleteMizuki Umino; Longjian Geng; Yusuke Ushiroda; Makoto Matsumoto; Hidefumi Mukai; Shigeru Kawakami
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Physiologically-Based Pharmacokinetic Modeling of Coproporphyrin I, an Endogenous OATP1B Substrate, in Cynomolgus Monkeys: Bridging the Inhibitory Effect of Rifampicin to Humans
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-02
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PREAI
deleteTakashi Yoshikado; Yukana Tomoda; Kouki Kasai; Reiki Toda; Satofumi Iida; Koji Chiba
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Advances in DDI evaluations: Recent trends from pre-clinical studies to regulatory submissions
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-01
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PREAI
deleteEmoto, Chie; Obach, R. Scott
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Glutathione-Reversible Inactivation of Aldehyde Oxidase by Hydralazine Contributes to Inter-lot Inhibition Variability in Human Hepatocytes
deleteDrug Metabolism and Pharmacokinetics
IF2.2
delete2026-04-01
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PREAI
deleteLloyd Wei Tat Tang
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