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Medicinal Chemistry Research cover

Medicinal Chemistry Research

IF3.1
Papers289
Citations6962
Journal Papers 266
Publication Date
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Bicyclononane-2,8-bis(trifluoromethyl)quinoline hybrids: synthesis, antiplasmodial and antitrypanosomal activity
deleteMedicinal Chemistry Research
IF3.1
delete2026-10-06
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deleteJohanna Dolensky; Werner Seebacher; Eva-Maria Pferschy-Wenzig; Miriam Zehentner; Robert Saf; Pascal Mäser; Monica Cal; Robert Weis
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From danger to resolution: targeting purinergic signaling in CNS diseases
deleteMedicinal Chemistry Research
IF3.1
delete2026-10-05
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deleteCamille Degryse; Kirti Gupta; Luc Buée; Thierry Burnouf; David Blum; Ming-Li Chou
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Vepdegestrant: the first FDA-approved oral PROTAC and a milestone in targeted protein degradation
deleteMedicinal Chemistry Research
IF3.1
delete2026-10-01
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deleteJeffrey Yang; Longqin Hu
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Baxdrostat (Baxfendy®), a first-in-class aldosterone synthase inhibitor approved for adults with uncontrolled hypertension
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-29
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deleteAhmed R. Ali; Longqin Hu
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Design and biological evaluation of sulfonamide–chalcone hybrids with in vitro tumor-selective cytotoxicity against oral squamous cell carcinoma: SAR, QSAR, and in silico ADME studies
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-29
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PREAI
deleteGulsen Ozli; Hiroshi Sakagami; M. Fatih Polat; Cavit Kazaz; Kota Kurosaki; Yoshihiro Uesawa; Kaito Inden; Halise Inci Gul
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Glypican-3-targeted bioconjugates for hepatocellular carcinoma: design, engineering, and translational applications
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-28
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deleteYi Liu; Jiaying Zhu; Haolei Yu; Chenyu Wang; Yue You; Zixuan Hong; Chenbo Zhang; Chenpengyu Zhang; Zhihao Zhang
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Optimization of a bis-imine scaffold as a glyoxalase I inhibitor: synthesis, SAR, and docking studies
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-28
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PREAI
deleteButhina A. Al-Oudat; Farah B. Al-Omari; Suaad A. Audat; Nizar A. Al-Shar’i; Qosay A. Al-Balas
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Pantoprazole as a potential repurposed drug targeting the adenosinergic system in esophageal cancer
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-25
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deleteAdriana Simioni; Rafael D Weimer; Julia B de Souza; Isadora V Citrini; Julia A da Rosa; Kaline Cardoso; Maria E Delawi; Luis FSM Timmers; Fernanda B Morrone
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Peptide-based allosteric modulators of AMPA receptors: design, docking and ligand-receptor interactions
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-24
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deleteTatiana V. Vyunova; Liudmila A. Andreeva; Konstantin V. Shevchenko; Valeriy P. Shevchenko; Igor Y. Nagaev; Andrey A. Butylin; Mstislav I. Lavrov; Vladimir A. Palyulin; Pavel E. Musienko; Nikolay F. Myasoedov
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Repurposing antifolates as G9a methyltransferase inhibitors for potential Alzheimer’s disease therapeutics via 3D QSAR/pharmacophore mapping and experimental validations
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-24
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deleteAbhisek Jana; Aina Bellver-Sanchis; Koushik Barman; Christian Griñán-Ferré; Deb Ranjan Banerjee
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Effect of pipernonaline from Piper retrofractum on memory disorder in mice and neurite outgrowth activity of PC12 cells
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-24
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PREAI
deleteRuna Fujimoto; Yuzuki Irie; Tohru Mitsunaga; Kosei Yamauchi
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An updated review of enantioselective syntheses and biological actions of carbanucleosides
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-24
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deleteSheila I. de Diego Saadia; Sergio H. Szajnman; Juan B. Rodriguez
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Artificial intelligence–assisted lead optimization in drug discovery: bridging computational advances and translational challenges
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-17
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PREAI
deleteFatma AlZahraa A. A. Mohamed; Ahmed Mohsen Kamal El-sagheir
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Probing novel azole–sulfonamide urea/thiourea conjugates as multitarget inhibitors of AChE and hCAs (I and II): synthesis, in vitro, and in silico studies
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-17
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deleteİrfan Çapan; Çağan Yasa; Yeliz Demir; Metin Güzelcan; Mohammed T. Qaoud; Yusuf Sert; İrfan Koca; İlhami Gülçin
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Unveiling the therapeutic potential of Calotropis procera: from traditional applications to phytochemistry, pharmacology, and safety
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-17
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deleteNitish Kumar; Rohit Singh Negi; Jyotirmayee Behera; Manjeet Kumar Sah Gond; Sunil Kumar Mishra
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O-methylation of phenolic natural products: translational insights from resveratrol
deleteMedicinal Chemistry Research
IF3.1
delete2026-09-10
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deleteSolomon Habtemariam
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Centanafadine (Simtriyo®): a first-in-class triple reuptake inhibitor approved for attention-deficit/hyperactivity disorder (ADHD)
deleteMedicinal Chemistry Research
IF3.1
delete2026-08-25
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deleteLongqin Hu
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Review of promising benzimidazole-based anticancer agents (2023-2026)
deleteMedicinal Chemistry Research
IF3.1
delete2026-08-21
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deleteElena Y. Shumilova; Sergey V. Sysolyatin; Svetlana V. Strokova
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Design, synthesis, biological activity and computational simulation evaluation of pyrimidine-2-aminoacetamide derivatives as cholinesterase inhibitors
deleteMedicinal Chemistry Research
IF3.1
delete2026-08-21
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deleteYi-Xuan Wang; Shi-Hao Qin; Qian Liu; Xue-Wei Zhou; Chao-Yue Zhang; Zheng-Yue Ma
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Zidesamtinib (Jideytro®): a new selective, brain-penetrant ROS1 inhibitor approved for the treatment of ROS1-positive non-small cell lung cancer
deleteMedicinal Chemistry Research
IF3.1
delete2026-08-18
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deleteSumi Lee; Longqin Hu
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