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Bioorganic and Medicinal Chemistry Letters

IF2.2
Papers352
Citations33083
Journal Papers 310
Publication Date
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Development of the fluorescence polarization-based competition assay for the E3 ligase GID4
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-27
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PREAI
deleteMeiling Zhang; Shijia Xiao; Kexin Yan; Jiyue Sun; Chen Xi; Yuhong Qin; Cheng Dong; Dongxing Chen
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Design, synthesis, and antiviral activity evaluation of the bis-ester prodrug of N4-hydroxycytidine phosphate
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-25
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PREAI
deleteHao Sun; Xu Yan; Chunhuan Mo; Jia Chen; Yan Liu; Yaohui Liu; Xia Han; Jianqin Gao; Lehua Yin; Jinghua Xu; Yuan Chen; Xinhua He
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Design, synthesis, and biological evaluation of novel 4-aminoquinoline derivatives as potent membrane-targeting antifungal agents
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-23
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PREAI
deleteJing Du; Wei Wang; Yanni Ma; Chaoyong Cui; Yuwan Zhang; Jian Yang; Rui Yang
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Alternariol from the endophytic fungus Alternaria sp. S4 acts as a membrane-targeting bactericidal agent against Staphylococcus aureus
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-23
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PREAI
deleteYanlin He; Yuwan Zhang; Wei Wang; Chaoyong Cui; Qianyun Hao; Hongguan Xie; Rui Yang
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Identification of a novel Songorine derivative as a potent NLRP3 inflammasome inhibitor
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-19
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PREAI
deleteRunqin Liu; Qiang Zhang; Miao Xian; Qifeng Chen
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Discovery and optimization of 2,3-Dihydroindole derivatives as STING receptor allosteric agonists
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-16
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PREAI
deleteYing Liu; Jing Wu; Ni Gao; Lin Zheng; Wenbo Zhang; Fabao Zhao; Bairu Meng; Xinyong Liu; Lanyu Liu; Huajun Zhao; Dongwei Kang
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N-[3-(4-(2-methoxyphenyl) piperazine-1-yl) propyl]-heteroaromatic carboxamide as selective α1A/1D-adrenoceptor antagonists: SAR study and metabolic stability evaluation
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-13
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PREAI
deleteRuxia Duan; Linxin Zhou; Ran Chen; Yajian Huang; Dan Wu; Tomohiko Ohwada; Wei Yi; Junjun Huang
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Design, synthesis, and antibacterial activity evaluation of tryptanthrin derivatives
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-11
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PREAI
deleteBing-Yuan Yan; Ran-Qi Feng; Chen Qu; Xu-Wen Li
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Design, synthesis and biological evaluation of ALK/HDAC dual-targeting agents
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-11
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PREAI
deleteYe Kong; Shunda Li; Xintong Xue; Huiping Liu; Ruiwei Fu; Yan Gao; Yingjie Zhang; Xia Xue
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Design, synthesis and biological evaluation of coumarin-based HDAC6 inhibitors for the treatment of ulcerative colitis
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-10
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PREAI
deleteXiang Qiu; Lingling Dong; Hongzhen Shu; Guangxing Yu; Yuling Tong; Hengfan Ni; Shunjie Zhang
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Identification of flavonoid-based small molecule inhibitors with dual-targeting capability against RdRp and Mpro of SARS-CoV-2
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-08
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PREAI
deleteYanlei Su; Yujia Wang; Jianyuan Zhao; Keyu Guo; Xuhong Duan; Honghai Wu; Dianxing Sun; Jing Zhang; Shan Cen
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A self-assembling peptide platform enables plasma membrane protein degradation
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-08
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PREAI
deleteWenjie Zhou; Yanyan Li; Wenli Shi; Binghua Cheng; Jiaming Liang; Zeyu Zhou; Hui Tian; Ximing Shao; Hongchang Li; Lijing Fang; Ke Liu
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A potent and selective RORγ inhibitor for the treatment of autoimmune diseases
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-08
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PREAI
deleteTaku Ikenogami; Masahiro Yokota; Shingo Fujioka; Naoki Ogawa; Masato Noguchi; Akihiro Nomura; Tsuyoshi Adachi; Yoshiaki Katsuda; Kojo Arita; Naoki Miyagawa; Yusuke Aratsu; Kota Asahina; Paul Crowe; Haiyan Tao; Scott Thacher; Makoto Shiozaki
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Synthesis and antitumor activity of derivatives of SKF-83566
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-08
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PREAI
deleteXiu-Jun Wang; Meng-Xin Lu; Qiu-yue Jin; Zi-Yan Lang; Ming-Li Yang; Jing Ji
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Bicyclic peptide-based CPPTACs for extracellular and cell membrane protein degradation
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-08
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PREAI
deleteJinyu Bai; Huaihuai Shi; Jitun Chen; Hui Tian; Jiaxin Liang; Bichun Chen; Jiazhong Li; Lijing Fang
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Design, synthesis, antifungal activity, and molecular docking studies of benzothiazole, S-benzyl-2,4-isodithiobiuret, and thiourea derivatives of 1-hepta-O-benzoyl-β-d-maltose nanoparticles
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-07
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PREAI
deleteShankesh C. Zyate; Nikita V. Awajare; Sanjay S. Gaikwad; Kunal Raut; Vikas Jha; Amardeep R. Jadhao; Poonam T. Agrawal
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Discovery of novel imidazo[4,5-b]pyridine derivatives as noncovalent reversible Bruton’s tyrosine kinase inhibitors
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-05
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deleteYeojeong Kim; Jingyang Sun; Kyoungyim Lee; Soobin Kim; Danbi Lee; Bomi Park; Yeji Lee; Inah Hwang; Jae-Sang Ryu
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Synthesis of new Pyridazinone derivatives and their dual inhibitory activity on aldose reductase and α-glucosidase
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-12-05
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PREAI
deleteMevlüt Akdağ; Merve Güneş Çam; Derya Ergen; Yeliz Demir; Şükrü Beydemir; Azime Berna Özçelik
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Exploring the therapeutic potential of deuterated PPARγ agonists for NASH
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-11-28
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PREAI
deleteXudong Pang; Dawei Cui; Ruifeng Liu; Binhua Lv; Cheng-Yun Wang
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Design, synthesis, and activity evaluation of alpinetin derivatives as potential anti-liver cancer drugs
deleteBioorganic & Medicinal Chemistry Letters
IF2.2
delete2025-11-27
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PREAI
deleteYanhui Yi; Yupei Sun; Xiangyang Zhang; Jianzeng Xin; Feng Zhao; Wei Zhu; Sheng Liu
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