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Clinical and Translational Science cover

Clinical and Translational Science

IF2.8
Papers2599
Citations5065
Journal Papers 2711
Publication Date
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A Multipart Phase 1 Study to Assess Safety and Pharmacokinetics of Ibuzatrelvir in Healthy Participants and Dose Selection for a Dose-Ranging Study
deleteClinical and Translational Science
IF2.8
delete2026-07-11
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deleteRavi Shankar P. Singh; Sima S. Toussi; Frances Hackman; Mona Shahbazi; John Prybylski; Siddhee A. Sahasrabudhe; Penelope Crownover; Eugene P. Kadar; Billy T. George; Negar Niki Alami; Arthur Bergman
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Machine Learning With Genetic and Clinical Data to Predict Ischemic Outcomes After PCI
deleteClinical and Translational Science
IF2.8
delete2026-07-09
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deleteCaroline W. Grant; Brenden S. Ingraham; Ryan J. Lennon; Anvi Raina; Shulan Tian; Gurukripa Kowlgi; Larisa H. Cavallari; Craig R. Lee; Amber Beitelshees; Dominick J. Angiolillo; Francesco Franchi; Julio D. Duarte; Joseph S. Rossi; George A. Stouffer; Eric Klee; Rajiv Gulati; Charanjit Rihal; Michael Farkouh; Arjun P. Athreya; Naveen L. Pereira
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Advancing PEGylated Drug Evaluation: A Novel Approach to Pegfilgrastim Pharmacokinetic Assessment
deleteClinical and Translational Science
IF2.8
delete2026-07-08
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deleteElizaveta Svyatova; Da Shi; Ankit Shah; Kristina E. Howard
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Circulating M-MDSC Expansion During Therapy Associates With Treatment Response in Multiple Myeloma: A Longitudinal Observational Study
deleteClinical and Translational Science
IF2.8
delete2026-06-29
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deleteQi Yan; Bin Chu; Mengru Liu; Na Ji; Shan Gao; Minqiu Lu; Lei Shi; Lijuan Fang; Qiuqing Xiang; Yuan Chen; Mengzhen Wang; Li Bao
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Development of a Biphasic Modified-Release Ibuprofen Tablet Formulation: Single-Dose and Multiple-Dose Pharmacokinetics and Food-Effect Studies
deleteClinical and Translational Science
IF2.8
delete2026-06-29
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deleteLudmila Kvapilová; Jiří Hofmann; Josef Černý; Tomáš Hauser; Mohammed Bouhajib; Martin Šíma; Ondřej Slanař
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PBPK Modeling and Clinical Data Reveal Reduced Impact of CYP3A4 and CYP2C9 Inhibitors on Elimination of Siponimod
deleteClinical and Translational Science
IF2.8
delete2026-06-27
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deleteFelix Huth; Kasra Shakeri-Nejad; Anne Gardin; Bharti Shah; Oliver Pohl; Nicole Pezous; Thomas Faller
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Drug Interactions of Vebreltinib, a Novel Type I c-Met Inhibitor, Coadministration With Rifampin or Itraconazole in Healthy Participants
deleteClinical and Translational Science
IF2.8
delete2026-06-25
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deleteJingcheng Chen; Jingxuan Wu; Yuqin Song; Jiangshuo Li; Linna li; Lijun Li; Yanhong Kong; Xiaofang Wu; Hang Yin; Mengyu Hou; Bingyan Wang; Qiannan Gao; Ran Li; Le Wu; Weizhe Xue; Ruihua Dong
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Model-Informed Development of a Subcutaneous Formulation of Tislelizumab: Phase 1 Pharmacokinetics in Patients With Cancer
deleteClinical and Translational Science
IF2.8
delete2026-06-23
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deleteXiangyu Liu; Ye Guan; Yixi Liu; Tian Yu; Ramil Abdrashitov; Ziru Niu; Xiao Lin; Xiaohan Ye; Yutong Wang; Srikumar Sahasranaman; William D. Hanley; Nageshwar Budha
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EPHX2 Orchestrates Intestinal Epithelial Barrier Repair in Ulcerative Colitis: An Integrated Multi-Omics and Experimental Study
deleteClinical and Translational Science
IF2.8
delete2026-06-23
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deleteTian Dai; Siyu Han; Xiaoping Hu; Jiakuo Gu; Dongmei Liu; Jiale Wu; Juyan Zheng; Shiqin Hong; Yiwen Zhang
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A Phase 1, Open-Label, Randomized Study to Investigate the Pharmacokinetics and Safety of Multiple Doses of Intranasal Naloxone in Healthy Participants
deleteClinical and Translational Science
IF2.8
delete2026-06-22
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deleteDavid Cassie; Bob Warnock; Faisal Akhtar; Duncan McCloskey; David Wyatt
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Benzbromarone as a Novel Candidate for Preventing Alzheimer's Disease: Evidence From Real-World Data Screening and in Vitro Validation
deleteClinical and Translational Science
IF2.8
delete2026-06-21
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deleteSho Sakagami; Yuya Yoshida; Shota Uemura; Taisei Kumamoto; Ryotaro Tsukamoto; Takumi Nishi; Shimpei Kawano; Kohei Fukuoka; Hanami Ino; Kengo Hamamura; Shigehiro Ohdo; Naoya Matsunaga
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From Pharmacodynamic Biomarker to Evaluating Treatment Response: Biomarkers in Primary Mitochondrial Diseases
deleteClinical and Translational Science
IF2.8
delete2026-06-19
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deleteSydney Stern; Karryn Crisamore; John Patton; Robert Schuck; Michael Pacanowski
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When Science Outpaces Infrastructure: People, Process, and Technology Challenges for Precision Dosing in Children
deleteClinical and Translational Science
IF2.8
delete2026-06-19
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deleteTamorah Lewis; Karim Jessa; Vijay Ivaturi; Andreas Noack; Dilum P. Aluthge; David Müller-Widmann; Kathryn Capello; Matthew Fong; Ashleigh Miatello; Melanie Barwick
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European Network on Optimizing Treatment With Therapeutic Antibodies in Chronic Inflammatory Diseases: Overview, Progress and Perspectives
deleteClinical and Translational Science
IF2.8
delete2026-06-19
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deleteKonstantin Tachkov; Merita Rumano; James Bluett; Nataša Bogavac-Stanojević; Erwin Dreesen; Mehmet Itik; Georgios Kararigas; Paweł Kawalec; Marlene Santos; Silje Skrede; Guenka Petrova; Denis Mulleman
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Predictive Factors for Relapse in Still's Disease: A Retrospective Cohort Study of Clinical and Laboratory Biomarkers
deleteClinical and Translational Science
IF2.8
delete2026-06-19
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deleteİbrahim Yahya Çakır; Abdulsamet Erden; Yeter Mahmutoğlu; Rıza Can Kardaş; Emine Uslu; Ertuğrul Çağrı Bölek; Serdar Sezer; Müçteba Enes Yayla; Hamit Küçük; Abdurrahman Tufan; Aşkın Ateş; Murat Turgay; Mehmet Akif Öztürk
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Challenges in Implementing Revocation of Oncology Drugs Under Conditional Early Approval in Japan: Regulatory Insights From Comparisons With FDA/EMA
deleteClinical and Translational Science
IF2.8
delete2026-06-18
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deleteTakahiro Handa; Arata Tanaka; Mayumi Shikano; Rika Wakao
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Transcriptomic Profiling of Cutaneous Melanoma Metastases Treated With Microwave Ablation—Pilot Study
deleteClinical and Translational Science
IF2.8
delete2026-06-18
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deletePurevsuren Losol; Daniel O'Driscoll; Andres Vallejo Pulido; Adrian von Witzleben; Konstantinos Boukas; Matthew Sommerlad; Christian Ottensmeier; Michael R. Ardern-Jones
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A Generative AI Framework for Pharmacokinetic Clinical Study Report Authoring
deleteClinical and Translational Science
IF2.8
delete2026-06-15
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deleteJohn Samuelsson; Samuel Blakeman; Ezra Alexander; Srividya Neelakantan; Ravi Shankar Prasad Singh; May Garrett; Allison Murphy; Jing Zhu; Subha Madhavan; Sheraz Khan
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Utilization of Healthy Volunteers in Oncology Drug Development in Japan: A 10-Year Analysis of Approved Anticancer Agents (2014–2024)
deleteClinical and Translational Science
IF2.8
delete2026-06-15
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deleteKana Morihisa; Hiroyuki Yoshitsugu; Hirokazu Wakuda; Naoto Uemura
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Interpretation of Chemistry, Hematology and Coagulation Laboratory Results in Early-Phase Clinical Pharmacology Trials; a Retrospective Analysis Based on the Placebo Arm of Randomized-Controlled Trials
deleteClinical and Translational Science
IF2.8
delete2026-06-13
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deleteJannik Rousel; Tessa Niemeyer-van der Kolk; Matthijs Moerland; Robert Rissmann; Naomi B. Klarenbeek; Maurits F. J. M. Vissers; Jacobus Burggraaf
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