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Briefings in Bioinformatics cover

Briefings in Bioinformatics

IF7.7
Papers5628
Citations27362
Journal Papers 5476
Publication Date
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Topological deep learning for drug–target interaction, virtual screening, and docking scoring: a practical, benchmark-driven review
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delete2026-07-12
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deleteBeatriz Suay-García; Antonio Falcó; null
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Deep learning models for cell cycle phase prediction from single-cell RNA sequencing data
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deleteHalima Akhter; Debra Piktel; Laura F Gibson; Gangqing Hu; Donald A Adjeroh
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MRDsteer: quality-aware AI-driven closed-loop optimization enhances ctDNA-based minimal residual disease detection
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deleteTianci Wang; Xin Lai; Shenjie Wang; Yuqian Liu; Shuqun Zhang; Jiayin Wang
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Advancing bioinformatics with language models: components, applications, and perspectives
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IF7.7
delete2026-07-10
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deleteJiajia Liu; Mengyuan Yang; Yankai Yu; Haixia Xu; Tiangang Wang; Kang Li; Xiaobo Zhou; null
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A graph retrieval-augmented generation pipeline for systematic drug target discovery: validation and application to ocular neovascularization
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deleteYongseok Mun; Dae Joong Ma; Ha Kyoung Kim; Kwangsic Joo; Sang Jun Park; Se Joon Woo; Kyu Hyung Park
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STGBench: sequencing-level spatial DNA–RNA simulation for multimodal and virtual cell-oriented benchmarking of genomic alterations
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IF7.7
delete2026-07-08
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deleteShenjie Wang; Yuhang Li; Xiaonan Wang; Xuwen Wang; Tianci Wang; Shuanying Yang; Jiayin Wang
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T-cell receptor alpha to beta chains binding prediction
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IF7.7
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deleteDevora Siminovsky; Yoram Louzoun
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SOPA and SIMPA: normalized single-sample integrated multiomics pathway analysis of tumor heterogeneity in solid cancers
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IF7.7
delete2026-07-08
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deleteHasan Alsharoh; Abdulrahman Ismaiel; George A Calin; Ovidiu L Pop; Ioana Berindan-Neagoe; Andreas Bender
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K-attention: a biologically informed attention operator for data-efficient sequence-based omics modeling
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delete2026-07-07
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deleteTao Liu; Jing-Yi Li; Ziyu Chen; Chan Gu; Tong Zhou; Shi-Qi Yang; Yang Ding; Ge Gao; null
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scImmuneCo: a compendium of cell-type-specific functional modules for decoding immune responses from single-cell RNA-seq data
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deleteFrank Qingyun Wang; Caicai Zhang; Xiao Dang; Huidong Su; Yao Lei; Youming Guo; Xinxin Chen; Wanling Yang; null
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Accurate prediction of asparagine deamidation in biologics using advanced machine learning models
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IF7.7
delete2026-07-07
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deleteShafayat Ahmed; Nicole Swope; Valentin Stanev; Romina Hofele; Dominique WuDunn; Rohan Jain; Jared Delmar; Maryam Pouryahya; null
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Exploring per-base quality scores as a surrogate marker of cell-free DNA fragmentome
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IF7.7
delete2026-07-06
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deleteHadas Volkov; Maria Raitses-Gurevich; Meitar Grad; Rani Shlayem; Dev Leibowitz; Tami Rubinek; Talia Golan; Noam Shomron
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METEOR: a data-adaptive Mendelian randomization method for powerful detection of shared and specific exposures underlying multiple outcomes
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deleteLiye Zhang; Ran Yan; Weiming Gong; Xiang Zhou; Lu Liu; Zhongshang Yuan
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FerroScore: a statistical approach for quantifying tumor-related ferroptosis based on omics data
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deleteJiaqi Teng; Qi Gong; Zhaohang Cai; Tianshou Zhou
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scGenoByte: a GenoByte embedding transformer with biological priors for cell type annotation
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delete2026-07-06
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deleteJiongsen Yao; Yong Xu; Jinjin Ma; Wenjun Shen; Si Wu
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Literature-informed gene extraction and ranking for multimodal data fusion
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IF7.7
delete2026-07-05
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deleteMarietta Hamberger; Silke D Werle; Johann M Kraus; Hans A Kestler; null
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Prediction of drug hypersensitivity by comprehensive modeling of HLA-peptidomes
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delete2026-07-03
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deleteYi Zhong; Volker M Lauschke; Yi Wang; Yitian Zhou
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DNA-DETR: sequence representation matters in object detection for functional genomic elements
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deleteBing-Shiun Tsai; Jin-Yung Wong; Huai-Kuang Tsai
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SA-MTP: a structure-aware framework for multifunctional therapeutic peptide annotation
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IF7.7
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deleteWenping Yu; Zhewen Li; Wei Xu; Yu Zhao; Nan Sun
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EssTFNet: integration of adaptive time–frequency and DNA language models for interpretable human essential gene prediction
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IF7.7
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deleteDong-Xin Ye; Shi-Shi Yuan; Wei Su; Hong-Qi Zhang; Rui Li; Ye-Chen Qi; Hao Lin; Nanqing Dong; Yan-Ting Jin
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