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Clinical Pharmacology and Therapeutics

IF5.5
Papers8636
Citations19410
Journal Papers 18350
Publication Date
Physiologically Motivated Sequential Population Modeling of Albumin Trends and Vedolizumab Pharmacokinetics for Pregnancy Dosing Regimen Optimization
delete2025-12-14
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deleteZrinka Duvnjak; Robin Michelet; Casper Steenholdt; Ella S.K. Widigson; Cæcilie Skejø; João A. Abrantes; Wilhelm Huisinga; Mette Julsgaard; Charlotte Kloft
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Navigating the Genetic Risk of Chemotherapy-Induced Hearing Loss in the Stria Vascularis
delete2025-12-05
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deleteTara Lazetic; Deanne Nixie R. Miao; Britt I. Drögemöller; Alain Dabdoub; Julia M. Abitbol
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Real-World Effectiveness and Safety of Recombinant Human Follicle-Stimulating Hormone (rhFSH) in Infertile Women undergoing Assisted Reproductive Technology (ART): A Korean Nationwide Cohort Study
delete2025-12-02
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deleteJoong Yeup Lee; Eun-Young Choi; Jung Ryeol Lee; Young Sik Choi; Ji Hyang Kim; Chang-Woo Choo; Yunju Choe; Hee-Jin Seo; Hyesung Lee; Yujeong Shin; Yejin Jeon; Ju-Young Shin; Hoon Kim
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Long-Read Sequencing Enhances Pharmacogenomic Profiling by Resolving Complex Haplotypes, Novel Star Alleles, and Structural Variants
delete2025-11-27
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PREAI
deleteSumudu Rangika Samarasinghe; Andrea Gaedigk; Jesse J. Swen; Henk-Jan Guchelaar; Shivashankar H. Nagaraj
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Bidirectional Interaction Between Liposomal Amphotericin B Pharmacokinetics and Parasite Dynamics in Patients With Post-Kala-Azar Dermal Leishmaniasis: Potential Implications for Optimal Dosing
delete2025-11-25
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deleteWan-Yu Chu; Om Prakash Singh; Shyam Sundar; Dinesh Mondal; Krishna Pandey; Pradeep Das; Ignace C. Roseboom; Sheeraz Raja; Ana Torres; Eugenia Carrillo; Alwin D.R. Huitema; Fabiana Alves; Thomas P.C. Dorlo
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Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers
delete2025-11-15
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deleteMarella Cornelia Elizabeth van Ruissen; Menno van Diemen; Liza Botros; Ingrid Tomljanovic; Hind Achbo; Dimitra Eleftheriou; Paul Willem Schenk; Naomi Bertine Klarenbeek; Derek William Gilroy; Manon Aleida Adriana Jansen; Matthijs Moerland
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Cystatin C-based eGFR better predicts renal vancomycin clearance than creatinine-based eGFR in patients with allogeneic stem cell transplantation
delete2025-11-12
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deleteEva-Maria A. Wansing; Sebastian G. Wicha; Peter Bannas; Alexander Heitkamp; Adrin Dadkhah; Nicolaus M. Kröger; Isabel Molwitz; Claudia Langebrake
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Enhancing Severe Neutropenia Prediction: PKPD-Informed Labeling for Machine Learning Models Trained on Real-World Data
delete2025-11-10
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deleteConor J O’Hanlon; Jonas Denck; Elif Ozkirimli; Stefanie Bendels; Candice Jamois; Clarisse Chavanne; Dirk Fey; Kimmo Porkka; Oscar Brück; Ken Wang
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Drug-Induced QT Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes
delete2025-11-09
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deleteOla Nordqvist; Olof Björneld; Patrick Bergman; Björn Wettermark; Alisa Lincke; Marine L. Andersson; Tora Hammar
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Respiratory Disorders Associated with Antibody–Drug Conjugates: A Combined Analysis of the French and the WHO Pharmacovigilance Databases
delete2025-11-07
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PREAI
deleteVictor Mirleau; Alex Hlavaty; Etienne-Marie Jutant; Florence Hennegrave; Kévin Bihan; Romane Freppel; Clément Cholle; Delphine Bourneau-Martin; Claire Lafay-Chebassier; Julien Mahé; Matthieu Bainaud; Marion Allouchery
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Evolving Standards: Good Clinical Practice Insights from US FDA, MHRA UK, and Health Canada
delete2025-11-05
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PREAI
deleteCheryl Grandinetti; Mandy Budwal-Jagait; Hocine Abid; Emily Gebbia; Elena Boley; LaKisha Williams; Andrew Fisher; Leigh Marcus; Laurie Muldowney; Jenn Sellers; Jason Wakelin-Smith; Kassa Ayalew
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Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease
delete2025-11-05
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deleteKei Irie; Phillip Minar; Jack Reifenberg; Brendan M. Boyle; Joshua D. Noe; Jeffrey S. Hyams; Tomoyuki Mizuno
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Model-Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia
delete2025-10-31
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deleteKelly M. Mahar; Shuying Yang; Brendan Johnson; Sandra A.G. Visser; Paul van den Berg; Martijn van Noort; Teun M. Post
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A Fast Path from Innovation to Safe and Effective Medicine
delete2025-10-28
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deletePeter Arlett; Falk Ehmann; Ralf Herold; Evdokia Korakianiti; Pierpaolo Moscariello; Liese Barbier; Iordanis Gravanis; Frank Pétavy; Emmanuel Cormier; Andrew Thomson; Spiros Vamvakas; Steffen Thirstrup
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