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5-HT1B receptor activation produces rapid antidepressant-like effects in rodents Clark, Erin A.; Wang, Lien; Hanania, Taleen; Kretschmannova, Karla; Bianchi, Massimiliano; Jagger, Elizabeth; Hu, Tingting; Li, Fugang; Gallero-Salas, Yasir; Koblan, Kenneth S.; Dedic, Nina; Bristow, Linda J. Share Save
A systematic assessment of robustness in CNS safety pharmacology Reiber, Maria; Stirling, Helen; Ahuis, Tim P.; Arias, Washington; Aulehner, Katharina; Dressler, Ute; Kas, Martien J. H.; Kela, Johanna; Kerker, Kimberly; Kuosmanen, Tarja; Lorenz, Helga; Pennington, Alexander T.; von Rueden, Eva-Lotta; Schauerte, Heike; Seiffert, Isabel; Talbot, Steven R.; Torturo, Christina; Virtanen, Sami; Waldron, Ann-Marie; Ramboz, Sylvie; Potschka, Heidrun Share Save
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Functional recovery following traumatic brain injury in rats is enhanced by oral supplementation with bovine thymus extract Surzenko, Natalia; Bastidas, Johana; Reid, Robert W.; Curaba, Julien; Zhang, Wei; Bostan, Hamed; Wilson, Mickey; Dominique, Ashley; Roberson, Julia; Ignacio, Glicerio; Komarnytsky, Slavko; Sanders, Alexa; Lambirth, Kevin; Brouwer, Cory R.; El-Khodor, Bassem F. Share Save
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Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau Foster, Kelly; Manca, Matteo; McClure, Kim; Koivula, Pyry; Trojanowski, John Q.; Havas, Daniel; Chancellor, Sarah; Goldstein, Lee; Brunden, Kurt R.; Kraus, Allison; Ahlijanian, Michael K. Share Save
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD Afroz, Tariq; Chevalier, Elodie; Audrain, Mickael; Dumayne, Christopher; Ziehm, Tamar; Moser, Roger; Egesipe, Anne-Laure; Mottier, Lorene; Ratnam, Monisha; Neumann, Manuela; Havas, Daniel; Ollier, Romain; Piorkowska, Kasia; Chauhan, Mayank; Silva, Alberto B.; Thapa, Samjhana; Stohr, Jan; Bavdek, Andrej; Eligert, Valerie; Adolfsson, Oskar; Nelson, Peter T.; Porta, Silvia; Lee, Virginia M. -Y.; Pfeifer, Andrea; Kosco-Vilbois, Marie; Seredenina, Tamara Share Save
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Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model Marchionini, Deanna M.; Liu, Jeh-Ping; Ambesi-Impiombato, Alberto; Kerker, Kimberly; Cirillo, Kim; Bansal, Mukesh; Mushlin, Rich; Brunner, Daniela; Ramboz, Sylvie; Kwan, Mei; Kuhlbrodt, Kirsten; Tillack, Karsten; Peters, Finn; Rauhala, Leena; Obenauer, John; Greene, Jonathan R.; Hartl, Christopher; Khetarpal, Vinod; Lager, Brenda; Rosinski, Jim; Aaronson, Jeff; Alam, Morshed; Signer, Ethan; Munoz-Sanjuan, Ignacio; Howland, David; Zeitlin, Scott O. Share Save
GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β-catenin and ALK5/SMAD2/3 pathways Frohlich, Jan; Kovacovicova, Kristina; Raffaele, Marco; Virglova, Tereza; Cizkova, Eliska; Kucera, Jan; Bienertova-Vasku, Julie; Wabitsch, Martin; Peyrou, Marion; Bonomini, Francesca; Rezzani, Rita; Chaldakov, George N.; Tonchev, Anton B.; Di Rosa, Michelino; Blavet, Nicolas; Hejret, Vaclav; Vinciguerra, Manlio Share Save
The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models Polinski, Nicole K.; Martinez, Terina N.; Ramboz, Sylvie; Sasner, Michael; Herberth, Mark; Switzer, Robert; Ahmad, Syed O.; Pelligrino, Lee J.; Clark, Sean W.; Marcus, Jacob N.; Smith, Sean M.; Dave, Kuldip D.; Frasier, Mark A. Share Save
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Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome Han, Zhou; Chen, Chunling; Christiansen, Anne; Ji, Sophina; Lin, Qian; Anumonwo, Charles; Liu, Chante; Leiser, Steven C.; Meena; Aznarez, Isabel; Liau, Gene; Isom, Lori L. Share Save
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease Zeitler, Bryan; Froelich, Steven; Marlen, Kimberly; Shivak, David A.; Yu, Qi; Li, Davis; Pearl, Jocelynn R.; Miller, Jeffrey C.; Zhang, Lei; Paschon, David E.; Hinkley, Sarah J.; Ankoudinova, Irina; Lam, Stephen; Guschin, Dmitry; Kopan, Lexi; Cherone, Jennifer M.; Nguyen, Hoang-Oanh B.; Qiao, Guijuan; Ataei, Yasaman; Mendel, Matthew C.; Amora, Rainier; Surosky, Richard; Laganiere, Josee; Vu, B. Joseph; Narayanan, Anand; Sedaghat, Yalda; Tillack, Karsten; Thiede, Christina; Gaertner, Annette; Kwak, Seung; Bard, Jonathan; Mrzljak, Ladislav; Park, Larry; Heikkinen, Taneli; Lehtimaki, Kimmo K.; Svedberg, Marie M.; Haggkvist, Jenny; Tari, Lenke; Toth, Miklos; Varrone, Andrea; Halldin, Christer; Kudwa, Andrea E.; Ramboz, Sylvie; Day, Michelle; Kondapalli, Jyothisri; Surmeier, D. James; Urnov, Fyodor D.; Gregory, Philip D.; Rebar, Edward J.; Munoz-Sanjuan, Ignacio; Zhang, H. Steve Share Save
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