Not logged in An integrated transcriptomic cell atlas of human endoderm-derived organoids Xu, Quan; Halle, Lennard; Hediyeh-zadeh, Soroor; Kuijs, Merel; Riedweg, Rya; Kilik, Umut; Recaldin, Timothy; Yu, Qianhui; Rall, Isabell; Frum, Tristan; Adam, Lukas; Parikh, Shrey; Kfuri-Rubens, Raphael; Gander, Manuel; Klein, Dominik; Curion, Fabiola; He, Zhisong; Fleck, Jonas Simon; Oost, Koen; Kahnwald, Maurice; Barbiero, Silvia; Mitrofanova, Olga; Maciag, Grzegorz Jerzy; Jensen, Kim B.; Lutolf, Matthias; Liberali, Prisca; Spence, Jason R.; Gjorevski, Nikolche; Beumer, Joep; Treutlein, Barbara; Theis, Fabian J.; Camp, J. Gray Share Save
Probe set selection for targeted spatial transcriptomics Kuemmerle, Louis B.; Luecken, Malte D.; Firsova, Alexandra B.; Andrade e Sousa, Lisa Barros de; Strasser, Lena; Mekki, Ilhem Isra; Campi, Francesco; Heumos, Lukas; Shulman, Maiia; Beliaeva, Valentina; Hediyeh-Zadeh, Soroor; Schaar, Anna C.; Mahbubani, Krishnaa T.; Sountoulidis, Alexandros; Balassa, Tamas; Kovacs, Ferenc; Horvath, Peter; Piraud, Marie; Erturk, Ali; Samakovlis, Christos; Theis, Fabian J. Share Save
ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia Behrens, Kira; Brajanovski, Natalie; Xu, Zhen; Viney, Elizabeth M.; Dirago, Ladina; Hediyeh-Zadeh, Soroor; Davis, Melissa J.; Pearson, Richard B.; Sanij, Elaine; Alexander, Warren S.; Ng, Ashley P. Share Save
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development Goh, Wilford; Sudholz, Harrison; Foroutan, Momeneh; Scheer, Sebastian; Pfefferle, Aline; Delconte, Rebecca B.; Meng, Xiangpeng; Shen, Zihan; Hennessey, Robert; Kong, Isabella Y.; Schuster, Iona S.; Andoniou, Christopher E.; Davis, Melissa J.; Hediyeh-Zadeh, Soroor; Souza-Fonseca-Guimaraes, Fernando; Parish, Ian A.; Beavis, Paul; Thiele, Daniel; Chopin, Michael; Degli-Esposti, Mariapia A.; Cursons, Joe; Kallies, Axel; Rautela, Jai; Nutt, Stephen L.; Huntington, Nicholas D. Share Save
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Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer Sharma, Shikhar; Chung, Chi-Yeh; Uryu, Sean; Petrovic, Jelena; Cao, Joan; Rickard, Amanda; Nady, Nataliya; Greasley, Samantha; Johnson, Eric; Brodsky, Oleg; Khan, Showkhin; Wang, Hui; Wang, Zhenxiong; Zhang, Yong; Tsaparikos, Konstantinos; Chen, Lei; Mazurek, Anthony; Lapek, John; Kung, Pei-Pei; Sutton, Scott; Richardson, Paul F.; Greenwald, Eric C.; Yamazaki, Shinji; Jones, Rhys; Maegley, Karen A.; Bingham, Patrick; Lam, Hieu; Stupple, Alexandra E.; Kamal, Aileen; Chueh, Anderly; Cuzzupe, Anthony; Morrow, Benjamin J.; Ren, Bin; Carrasco-Pozo, Catalina; Tan, Chin Wee; Bhuva, Dharmesh D.; Allan, Elizabeth; Surgenor, Elliot; Vaillant, Francois; Pehlivanoglu, Havva; Falk, Hendrik; Whittle, James R.; Newman, Janet; Cursons, Joseph; Doherty, Judy P.; White, Karen L.; Macpherson, Laura; Devlin, Mark; Dennis, Matthew L.; Hattarki, Meghan K.; De Silva, Melanie; Camerino, Michelle A.; Butler, Miriam S.; Dolezal, Olan; Pilling, Patricia; Foitzik, Richard; Stupple, Paul A.; Lagiakos, H. Rachel; Walker, Scott R.; Hediyeh-Zadeh, Soroor; Nuttall, Stewart; Spall, Sukhdeep; Charman, Susan A.; Connor, Theresa; Peat, Thomas S.; Avery, Vicky M.; Bozikis, Ylva E.; Yang, Yuqing; Zhang, Ming; Monahan, Brendon J.; Voss, Anne K.; Street, Ian P.; Dawson, Sarah-Jane; Dawson, Mark A.; Lindeman, Geoffrey J.; Davis, Melissa J.; Visvader, Jane E.; Paul, Thomas A. Share Save
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MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms Chi, Lap Hing; Cross, Ryan S. N.; Redvers, Richard P.; Davis, Melissa; Hediyeh-zadeh, Soroor; Mathivanan, Suresh; Samuel, Monisha; Lucas, Erin C.; Mouchemore, Kellie; Gregory, Philip A.; Johnstone, Cameron N.; Anderson, Robin L. Share Save
SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia Brown, Lauren M.; Hediyeh-Zadeh, Soroor; Sadras, Teresa; Huckstep, Hannah; Sandow, Jarrod J.; Bartolo, Ray C.; Kosasih, Hansen J.; Davidson, Nadia M.; Schmidt, Breon; Bjelosevic, Stefan; Johnstone, Ricky; Webb, Andrew, I; Khaw, Seong L.; Oshlack, Alicia; Davis, Melissa J.; Ekert, Paul G. Share Save
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death El-Saafin, Farrah; Bergamasco, Maria, I; Chen, Yunshun; May, Rose E.; Esakky, Prabagaran; Hediyeh-zadeh, Soroor; Dixon, Mathew; Wilcox, Stephen; Davis, Melissa J.; Strasser, Andreas; Smyth, Gordon K.; Thomas, Tim; Voss, Anne K. Share Save
Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity Grisaru-Tal, Sharon; Dulberg, Shai; Beck, Lir; Zhang, Chunyan; Itan, Michal; Hediyeh-Zadeh, Soroor; Caldwell, Julie; Rozenberg, Perri; Dolitzky, Avishay; Avlas, Shmuel; Hazut, Inbal; Gordon, Yaara; Shani, Ophir; Tsuriel, Shlomo; Gerlic, Motti; Erez, Neta; Jacquelot, Nicolas; Belz, Gabrielle T.; Rothenberg, Marc E.; Davis, Melissa J.; Yu, Hua; Geiger, Tamar; Madi, Asaf; Munitz, Ariel Share Save
SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation Adolphe, Christelle; Millar, Amanda; Kojic, Marija; Barkauskas, Deborah S.; Sundstrom, Anders; Swartling, Fredrik J.; Hediyeh-Zadeh, Soroor; Tan, Chin Wee; Davis, Melissa J.; Genovesi, Laura A.; Wainwright, Brandon J. Share Save
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma Jacquelot, Nicolas; Seillet, Cyril; Wang, Minyu; Pizzolla, Angela; Liao, Yang; Hediyeh-zadeh, Soroor; Grisaru-Tal, Sharon; Louis, Cynthia; Huang, Qiutong; Schreuder, Jaring; Souza-Fonseca-Guimaraes, Fernando; de Graaf, Carolyn A.; Thia, Kevin; Macdonald, Sean; Camilleri, Mary; Luong, Kylie; Zhang, Shengbo; Chopin, Michael; Molden-Hauer, Tristan; Nutt, Stephen L.; Umansky, Viktor; Ciric, Bogoljub; Groom, Joanna R.; Foster, Paul S.; Hansbro, Philip M.; McKenzie, Andrew N. J.; Gray, Daniel H. D.; Behren, Andreas; Cebon, Jonathan; Vivier, Eric; Wicks, Ian P.; Trapani, Joseph A.; Munitz, Ariel; Davis, Melissa J.; Shi, Wei; Neeson, Paul J.; Belz, Gabrielle T. Share Save
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype Kojic, Marija; Gawda, Tomasz; Gaik, Monika; Begg, Alexander; Salerno-Kochan, Anna; Kurniawan, Nyoman D.; Jones, Alun; Drozdzyk, Katarzyna; Koscielniak, Anna; Chramiec-Glabik, Andrzej; Hediyeh-Zadeh, Soroor; Kasherman, Maria; Shim, Woo Jun; Sinniah, Enakshi; Genovesi, Laura A.; Abrahamsen, Rannva K.; Fenger, Christina D.; Madsen, Camilla G.; Cohen, Julie S.; Fatemi, Ali; Stark, Zornitza; Lunke, Sebastian; Lee, Joy; Hansen, Jonas K.; Boxill, Martin F.; Keren, Boris; Marey, Isabelle; Saenz, Margarita S.; Brown, Kathleen; Alexander, Suzanne A.; Mureev, Sergey; Batzilla, Alina; Davis, Melissa J.; Piper, Michael; Boden, Mikael; Burne, Thomas H. J.; Palpant, Nathan J.; Moller, Rikke S.; Glatt, Sebastian; Wainwright, Brandon J. Share Save
Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance Goh, Wilford; Scheer, Sebastian; Jackson, Jacob T.; Hediyeh-Zadeh, Soroor; Delconte, Rebecca B.; Schuster, Iona S.; Andoniou, Christopher E.; Rautela, Jai; Degli-Esposti, Mariapia A.; Davis, Melissa J.; McCormack, Matthew P.; Nutt, Stephen L.; Huntington, Nicholas D. Share Save
Eukaryote-ConservedMethylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia Emery-Corbin, Samantha J.; Hamey, Joshua J.; Ansell, Brendan R. E.; Balan, Balu; Tichkule, Swapnil; Stroehlein, Andreas J.; Cooper, Crystal; McInerney, Bernie, V; Hediyeh-Zadeh, Soroor; Vuong, Daniel; Crombie, Andrew; Lacey, Ernest; Davis, Melissa J.; Wilkins, Marc R.; Bahlo, Melanie; Svard, Staffan G.; Gasser, Robin B.; Jex, Aaron R. Share Save
Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell-matrix adhesion Wee, Kenneth; Hediyeh-Zadeh, Soroor; Duszyc, Kinga; Verma, Suzie; Nanavati, Bageshri N.; Khare, Satyajeet; Varma, Amrita; Daly, Roger J.; Yap, Alpha S.; Davis, Melissa J.; Budnar, Srikanth Share Save
Cotargeting BCL-2 and MCL-1 in high-risk B-ALL Moujalled, Donia M.; Hanna, Diane T.; Hediyeh-zadeh, Soroor; Pomilio, Giovanna; Brown, Lauren; Litalien, Veronique; Bartolo, Ray; Fleming, Shaun; Chanrion, Maia; Banquet, Sebastien; Maragno, Ana-Leticia; Kraus-Berthier, Laurence; Schoumacher, Marie; Mullighan, Charles G.; Georgiou, Angela; White, Christine A.; Lessene, Guillaume; Huang, David C. S.; Roberts, Andrew W.; Geneste, Olivier; Rasmussen, Lorna; Davis, Melissa J.; Ekert, Paul G.; Wei, Andrew; Ng, Ashley P.; Khaw, Seong L. Share Save
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