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Early-Stage Flow Process Development of a Key Intermediate toward PF-07265807, an AXL-MER Inhibitor Oncology Candidate Armstrong, Cameron T.; Grohowalski, Katharina; Russell, Grace; Mason, Sara; Nandiwale, Kakasaheb Y.; Edwards, DaQuawn; Sheeran, Jillian; Steiman, Talia J.; Critcher, Douglas J.; Ashcroft, Christopher P.; Diaz, Angel R.; Guinness, Steven M. Share Save
Scalable Quasi-Divided Cell Operation Using Spinning Cylinder Electrode Technology: Multigram Electrochemical Synthesis of an Axitinib Intermediate Malviya, Bhanwar K.; Hansen, Eric C.; Kong, Caleb J.; Imbrogno, Joseph; Verghese, Jenson; Guinness, Steven M.; Salazar, Chase A.; Desrosiers, Jean-Nicolas; Kappe, C. Oliver; Cantillo, David Share Save
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Metal-Free Electrochemical Reduction of Disulfides in an Undivided Cell under Mass Transfer Control Malviya, Bhanwar K.; Hansen, Eric C.; Kong, Caleb J.; Imbrogno, Joseph; Verghese, Jenson; Guinness, Steven M.; Salazar, Chase A.; Desrosiers, Jean-Nicolas; Kappe, C. Oliver; Cantillo, David Share Save
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Small footprint liquid chromatography-mass spectrometry for pharmaceutical reaction monitoring and automated process analysis Hemida, Mohamed; Haddad, Paul R.; Lam, Shing C.; Coates, Lewellwyn J.; Riley, Frank; Diaz, Angel; Gooley, Andrew A.; Wirth, Hans-Juergen; Guinness, Steven; Sekulic, Sonja; Paull, Brett Share Save
Process Development of a Second Generation β-Amyloid-Cleaving Enzyme Inhibitor-Improving the Robustness of a Halogen-Metal Exchange Using Continuous Stirred-Tank Reactors Li, Bryan; Barnhart, Richard W.; Dion, Amelie; Guinness, Steven; Happe, Alan; Hayward, Cheryl M.; Kohrt, Jeffrey; Makowski, Teresa; Maloney, Mark; Nelson, Jade D.; Nematalla, Asaad; McWilliams, J. Christopher; Peng, Zhihui; Raggon, Jeffrey; Sagal, John; Weisenburger, Gerald A.; Bao, Denghui; Gonzalez, Miguel; Lu, Jiangping; McLaws, Mark D.; Tao, Jian; Wu, Baolin Share Save
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Continuous Production of Anhydrous tert-Butyl Hydroperoxide in Nonane Using Membrane Pervaporation and Its Application in Flow Oxidation of a γ-Butyrolactam Li, Bryan; Guinness, Steven M.; Hoagland, Steve; Fichtner, Michael; Kim, Hui; Li, Shelly; Maguire, Robert J.; McWilliams, J. Christopher; Mustakis, Jason; Raggon, Jeffrey; Campos, Dan; Voss, Chris R.; Sohodski, Evan; Feyock, Bryan; Murnen, Hannah; Gonzalez, Miguel; Johnson, Matthew; Lu, Jiangping; Feng, Xichun; Sung, Xingfang; Zheng, Songyuan; Wu, Baolin Share Save
Palbociclib Commercial Manufacturing Process Development. Part III. Deprotection Followed by Crystallization for API Particle Property Control Cheka, Brian P.; Ewers, Jason; Guinness, Steven M.; Ide, Nathan D.; Leeman, Kyle R.; Post, Ronald J.; Rane, Anil M.; Sutherland, Karen; Wang, Ke; Webster, Mark; Withbroe, Gregory J.; Draper, John; Lynch, Denis; McAuliffe, Marie; Keane, Joseph Share Save
Development of an Efficient Pd-Catalyzed Coupling Process for Axitinib Chekal, Brian P.; Guinness, Steven M.; Lillie, Brett M.; McLaughlin, Robert W.; Palmer, Charles W.; Post, Ronald J.; Sieser, Janice E.; Singer, Robert A.; Sluggett, Gregory W.; Vaidyanathan, Rajappa; Withbroe, Gregory J. Share Save
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