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POLRMT overexpression increases mtDNA transcription without affecting steady-state mRNA levels Miranda, Maria; Mesaros, Andrea; Scrima, Nathalie; Perard, Louise; Kuznetsova, Irina; Purrio, Martin; Atanassov, Ilian; Filipovska, Aleksandra; Mourier, Arnaud; Larsson, Nils-Goran; Kuhl, Inge Share Save
Mitochondrial damage in muscle specific PolG mutant mice activates the integrated stress response and disrupts the mitochondrial folate cycle Bond, Simon T.; King, Emily J.; Walker, Shannen M.; Yang, Christine; Liu, Yingying; Liu, Kevin H.; Zhuang, Aowen; Jurrjens, Aaron W.; Fang, Haoyun A.; Formosa, Luke E.; Nath, Artika P.; Carmona, Sergio Ruiz; Inouye, Michael; Duong, Thy; Huynh, Kevin; Meikle, Peter J.; Crawford, Simon; Ramm, Georg; Elahee Doomun, Sheik Nadeem; de Souza, David P.; Rudler, Danielle L.; Calkin, Anna C.; Filipovska, Aleksandra; Greening, David W.; Henstridge, Darren C.; Drew, Brian G. Share Save
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Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network Lee, Richard G.; Rudler, Danielle L.; Raven, Samuel A.; Peng, Liuyu; Chopin, Anaelle; Moh, Edward S. X.; Mccubbin, Tim; Siira, Stefan J.; Fagan, Samuel V.; Debono, Nicholas J.; Stentenbach, Maike; Browne, Jasmin; Rackham, Filip F.; Li, Ji; Simpson, Kaylene J.; Marcellin, Esteban; Packer, Nicolle H.; Reid, Gavin E.; Padman, Benjamin S.; Rackham, Oliver; Filipovska, Aleksandra Share Save
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Temporal landscape of mitochondrial proteostasis governed by the UPRmt Uoselis, Louise; Lindblom, Runa; Lam, Wai Kit; Kung, Catharina J.; Skulsuppaisarn, Marvin; Khuu, Grace; Nguyen, Thanh N.; Rudler, Danielle L.; Filipovska, Aleksandra; Schittenhelm, Ralf B.; Lazarou, Michael Share Save
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription Dai, Chuan-Yang; Ng, Chai Chee; Hung, Grace Ching Ching; Kirmes, Ina; Hughes, Laetitia A. A.; Du, Yunguang; Brosnan, Christopher A. A.; Ahier, Arnaud; Hahn, Anne; Haynes, Cole M. M.; Rackham, Oliver; Filipovska, Aleksandra; Zuryn, Steven Share Save
Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer Stentenbach, Maike; Ermer, Judith A.; Rudler, Danielle L.; Perks, Kara L.; Raven, Samuel A.; Lee, Richard G.; McCubbin, Tim; Marcellin, Esteban; Siira, Stefan J.; Rackham, Oliver; Filipovska, Aleksandra Share Save
Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation Hughes, Laetitia A.; Rudler, Danielle L.; Siira, Stefan J.; McCubbin, Tim; Raven, Samuel A.; Browne, Jasmin M.; Ermer, Judith A.; Rientjes, Jeanette; Rodger, Jennifer; Marcellin, Esteban; Rackham, Oliver; Filipovska, Aleksandra Share Save
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ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing Clemente, Paula; Calvo-Garrido, Javier; Pearce, Sarah F.; Schober, Florian A.; Shigematsu, Megumi; Siira, Stefan J.; Laine, Isabelle; Spahr, Henrik; Steinmetzger, Christian; Petzold, Katja; Kirino, Yohei; Wibom, Rolf; Rackham, Oliver; Filipovska, Aleksandra; Rorbach, Joanna; Freyer, Christoph; Wredenberg, Anna Share Save
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion Misic, Jelena; Milenkovic, Dusanka; Al-Behadili, Ali; Xie, Xie; Jiang, Min; Jiang, Shan; Filograna, Roberta; Koolmeister, Camilla; Siira, Stefan J.; Jenninger, Louise; Filipovska, Aleksandra; Clausen, Anders R.; Caporali, Leonardo; Valentino, Maria Lucia; La Morgia, Chiara; Carelli, Valerio; Nicholls, Thomas J.; Wredenberg, Anna; Falkenberg, Maria; Larsson, Nils-Goran Share Save
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Computationally designed hyperactive Cas9 enzymes Vos, Pascal D.; Rossetti, Giulia; Mantegna, Jessica L.; Siira, Stefan J.; Gandadireja, Andrianto P.; Bruce, Mitchell; Raven, Samuel A.; Khersonsky, Olga; Fleishman, Sarel J.; Filipovska, Aleksandra; Rackham, Oliver Share Save
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