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Alexander Rich

Johns Hopkins University

119H-index
602Paper Count
5.4WCitation Count
Published Papers 70
Publication Date
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Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-07-25
err0
errOAAI
errRich, Alexander S.; Chan, Yvonne H.; Birnbaum, Benjamin; Haider, Kamran; Haimson, Joshua; Hale, Michael; Han, Yongxin; Hickman, William; Hoeflich, Klaus P.; Ortwine, Daniel; Ozen, Aysegul; Belanger, David
errShare
errSave
Postprediction Inference for Clinical Characteristics Extracted With Machine Learning on Electronic Health Records
errJCO CLINICAL CANCER INFORMATICS
IF2.8
err2023-05-01
err0
errOAAI
errSondhi, Arjun; Rich, Alexander S.; Wang, Siruo; Leek, Jeffery T.
errShare
errSave
A machine learning framework supporting prospective clinical decisions applied to risk prediction in oncology
errNPJ DIGITAL MEDICINE
IF15.1
err2022-08-16
err12
errOAAI
errCoombs, Lorinda; Orlando, Abigail; Wang, Xiaoliang; Shaw, Pooja; Rich, Alexander S.; Lakhtakia, Shreyas; Titchener, Karen; Adamson, Blythe; Miksad, Rebecca A.; Mooney, Kathi
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errSave
AI reflections in 2019
errNATURE MACHINE INTELLIGENCE
IF23.9
err2020-01-17
err6
PREAI
errRich, Alexander S.; Rudin, Cynthia; Jacoby, David M. P.; Freeman, Robin; Wearn, Oliver R.; Shevlin, Henry; Dihal, Kanta; Oheigeartaigh, Sean S.; Butcher, James; Lippi, Marco; Palka, Przemyslaw; Torroni, Paolo; Wongvibulsin, Shannon; Begoli, Edmon; Schneider, Gisbert; Cave, Stephen; Sloane, Mona; Moss, Emmanuel; Rahwan, Iyad; Goldberg, Ken; Howard, David; Floridi, Luciano; Stilgoe, Jack
errShare
errSave
Lessons for artificial intelligence from the study of natural stupidity
errNATURE MACHINE INTELLIGENCE
IF23.9
err2019-04-09
err51
PREAI
errRich, Alexander S.; Gureckis, Todd M.
errShare
errSave
The Limits of Learning: Exploration, Generalization, and the Development of Learning Traps
errJOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
IF3.5
err2018-11-01
err42
errOAAI
errRich, Alexander S.; Gureckis, Todd M.
errShare
errSave
Epigenetic Regulation by Z-DNA Silencer Function Controls Cancer-Associated ADAM-12 Expression in Breast Cancer: Cross-talk between MeCP2 and NF1 Transcription Factor Family
errCANCER RESEARCH
IF16.6
err2013-01-16
err49
errOAAI
errRay, Bimal K.; Dhar, Srijita; Henry, Carolyn; Rich, Alexander; Ray, Alpana
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errSave
Solution structure of the Zβ domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2011-04-06
err35
errOAAI
errKim, Kyungmin; Khayrutdinov, Bulat I.; Lee, Chung-Kyung; Cheong, Hae-Kap; Kang, Sung Wook; Park, Hyejin; Lee, Sangho; Kim, Yang-Gyun; Jee, JunGoo; Rich, Alexander; Kim, Kyeong Kyu; Jeon, Young Ho
errShare
errSave
Crystal structure of a junction between two Z-DNA helices
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2010-05-03
err40
errOAAI
errde Rosa, Matteo; de Sanctis, Daniele; Rosario, Ana Lucia; Archer, Margarida; Rich, Alexander; Athanasiadis, Alekos; Carrondo, Maria Armenia
errShare
errSave
The Era of RNA Awakening: Structural biology of RNA in the early years
errQUARTERLY REVIEWS OF BIOPHYSICS
IF5.3
err2009-07-29
err22
PREAI
errRich, Alexander
errShare
errSave
Base extrusion is found at helical junctions between right- and left-handed forms of DNA and RNA
errNUCLEIC ACIDS RESEARCH
IF13.1
err2009-05-21
err33
errOAAI
errKim, Doyoun; Reddy, Sanjith; Kim, Dong Young; Rich, Alexander; Lee, Sangho; Kim, Kyeong Kyu; Kim, Yang-Gyun
errShare
errSave
The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2008-12-30
err118
errOAAI
errHa, Sung Chul; Kim, Doyoun; Hwang, Hye-Yeon; Rich, Alexander; Kim, Yang-Gyun; Kim, Kyeong Kyu
errShare
errSave
The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZADAR1
errNUCLEIC ACIDS RESEARCH
IF13.1
err2008-12-11
err55
errOAAI
errHa, Sung Chul; Choi, Jongkeun; Hwang, Hye-Yeon; Rich, Alexander; Kim, Yang-Gyun; Kim, Kyeong Kyu
errShare
errSave
Characterization of DNA-binding activity of Z α domains from poxviruses and the importance of the β-wing regions in converting B-DNA to Z-DNA
errNUCLEIC ACIDS RESEARCH
IF13.1
err2007-11-26
err24
errOAAI
errVan Quyen, Dong; Ha, Sung Chul; Lowenhaupt, Ky; Rich, Alexander; Kim, Kyeong Kyu; Kim, Yang-Gyun
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errSave
Characterization of Z-DNA as a nucleosome-boundary element in yeast Saccharomyces cerevisiae
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2007-02-13
err72
errOAAI
errWong, Ben; Chen, Shuai; Kwon, Jin-Ah; Rich, Alexander
errShare
errSave
A peptide with alternating lysines can act as a highly specific Z-DNA binding domain
errNUCLEIC ACIDS RESEARCH
IF13.1
err2006-09-18
err15
errOAAI
errKim, Yang-Gyun; Park, Hyun-Ju; Kim, Kyeong Kyu; Lowenhaupt, Ky; Rich, Alexander
errShare
errSave
Discovery of the hybrid helix and the first DNA-RNA hybridization
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2006-03-01
err35
PREAI
errRich, A
errShare
errSave
RNA processing in evolution - The logic of soft-wired genomes
errMOLECULAR STRATEGIES IN BIOLOGICAL EVOLUTION
IF0
err2006-02-06
err25
PREAI
errHerbert, A; Rich, A
errShare
errSave
Biological function of the vaccinia virus Z-DNA-binding protein E3L: Gene transactivation and antiapoptotic activity in HeLa cells
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2005-08-26
err89
errOAAI
errKwon, JA; Rich, A
errShare
errSave
A PKR-like eukaryotic initiation factor 2α kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2005-01-19
err174
errOAAI
errRothenburg, S; Deigendesch, N; Dittmar, K; Koch-Nolte, F; Haag, F; Lowenhaupt, K; Rich, A
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
L
Luciano Floridi
H-index: 111 · Papers: 961
G
Gary Felsenfeld
H-index: 101 · Papers: 299
A
Alan R. Fersht
H-index: 94 · Papers: 345
J
Joel L. Sussman
H-index: 92 · Papers: 510
S
Shuguang Zhang
H-index: 90 · Papers: 427
View more