Sam Chen - Publications, H-index & Citations

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Sam Chen

integrated nanotherapeutics inc., burnaby, bc v5g 4x4, canada

24H-index

50Paper Count

5.9KCitation Count

Published Papers 20

Publication Date

Radiosensitization by Docetaxel Prodrug-Loaded Lipid Nanoparticles in Pancreatic Cancer Xenografts

Nanomaterials 2025, Vol. 15, Page 1521

IF4.3

2025-10-05

OAAI

Abdulaziz Alhussan; Nolan Jackson; Nancy Dos Santos; Sam Chen; Yuen Yi C. Tam; Devika B. Chithrani

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Modeling the effect of pitting on the tensile behavior of amorphous carbon and carbon fiber

Carbon Trends

IF3.9

2025-08-05

OAAI

Victoria Arias; Sam Chen; Justin B. Haskins; Francesco Panerai; Harley T. Johnson; Kelly A. Stephani

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Lipid Nanoparticle and Liposome Reference Materials: Assessment of Size Homogeneity and Long-Term-70 °C and 4 °C Storage Stability

LANGMUIR

IF3.9

2023-02-07

OAAI

Jakubek, Zygmunt J.; Chen, Sam; Zaifman, Josh; Tam, Yuen Yi C.; Zou, Shan

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Development of lipid nanoparticles and liposomes reference materials (II): cytotoxic profiles

SCIENTIFIC REPORTS

IF3.9

2022-10-27

OAAI

Syama, Krishnapriya; Jakubek, Zygmunt J.; Chen, Sam; Zaifman, Josh; Tam, Yuen Yi C.; Zou, Shan

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Long-Term Patient-Reported Outcomes of Ultrasound-Guided Carpal Tunnel Release

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

IF3.4

2022-10-17

OAAI

Lee, Anson Y.; Weldon, Noah; Jackels, Melissa; Lawton, Dylan; Chen, Sam

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Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery

SMALL

IF12.1

2021-08-01

OAAI

van Der Meel, Roy; Chen, Sam; Zaifman, Josh; Kulkarni, Jayesh A.; Zhang, Xu Ran S.; Tam, Ying K.; Bally, Marcel B.; Schiffelers, Raymond M.; Ciufolini, Marco A.; Cullis, Pieter R.; Tam, Yuen Yi C.

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The current landscape of nucleic acid therapeutics (vol 16, pg 630, 2021)

NATURE NANOTECHNOLOGY

IF34.9

2021-06-30

OAAI

Kulkarni, Jayesh A.; Witzigmann, Dominik; Thomson, Sarah B.; Chen, Sam; Leavitt, Blair R.; Cullis, Pieter R.; van der Meel, Roy

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Scalable Production of Lipid Nanoparticles Containing Amphotericin B

LANGMUIR

IF3.9

2021-06-08

PREAI

Kulkarni, Jayesh A.; Chen, Sam; Tam, Yuen Yi C.

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The current landscape of nucleic acid therapeutics

NATURE NANOTECHNOLOGY

IF34.9

2021-05-31

795

OAAI

Kulkarni, Jayesh A.; Witzigmann, Dominik; Thomson, Sarah B.; Chen, Sam; Leavitt, Blair R.; Cullis, Pieter R.; van der Meel, Roy

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Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach

LANGMUIR

IF3.9

2021-01-13

OAAI

Terada, Takeshi; Kulkarni, Jayesh A.; Huynh, Ariel; Chen, Sam; van der Meel, Roy; Tam, Yuen Yi C.; Cullis, Pieter R.

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Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan

CIRCULATION RESEARCH

IF16.2

2020-05-08

OAAI

Roberts, Morgan E.; Barvalia, Maunish; Silva, Jessica A. F. D.; Cederberg, Rachel A.; Chu, William; Wong, Amanda; Tai, Daven C.; Chen, Sam; Matos, Israel; Priatel, John J.; Cullis, Pieter R.; Harder, Kenneth W.

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Lipid nanoparticle technology for therapeutic gene regulation in the liver

ADVANCED DRUG DELIVERY REVIEWS

IF17.6

2020-01-01

240

OAAI

Witzigmann, Dominik; Kulkarni, Jayesh A.; Leung, Jerry; Chen, Sam; Cullis, Pieter R.; van der Meel, Roy

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Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2019-08-09

332

OAAI

Kulkarni, Jayesh A.; Witzigmann, Dominik; Chen, Sam; Cullis, Pieter R.; van der Meel, Roy

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On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA

ACS NANO

IF16

2018-04-03

390

OAAI

Kulkarni, Jayesh A.; Darjuan, Maria M.; Mercer, Joanne E.; Chen, Sam; van der Meel, Roy; Thewalt, Jenifer L.; Tam, Yuen Yi C.; Cullis, Pieter R.

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Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes

MOLECULAR METABOLISM

IF6.6

2017-10-01

OAAI

Neumann, Ursula H.; Ho, Jessica S. S.; Chen, Sam; Tam, Yuen Yi C.; Cullis, Pieter R.; Kieffer, Timothy J.

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Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles

NANOSCALE

IF5.1

2017-01-01

PREAI

Kulkarni, Jayesh A.; Tam, Yuen Yi C.; Chen, Sam; Tam, Ying K.; Zaifman, Josh; Cullis, Pieter R.; Biswas, Souvik

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The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA

MOLECULAR THERAPY

IF12

2016-12-01

OAAI

Wang, Haitang; Tam, Yuen Yi C.; Chen, Sam; Zaifman, Josh; van der Meel, Roy; Ciufolini, Marco A.; Cullis, Pieter R.

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IGFBP2 Is Neither Sufficient nor Necessary for the Physiological Actions of Leptin on Glucose Homeostasis in Male ob/ob Mice

ENDOCRINOLOGY

IF3.3

2014-03-01

OAAI

Neumann, Ursula H.; Chen, Sam; Tam, Yuen Yi C.; Baker, Robert K.; Covey, Scott D.; Cullis, Pieter R.; Kieffer, Timothy J.

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Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2013-01-01

357

OAAI

Mui, Barbara L.; Tam, Ying K.; Jayaraman, Muthusamy; Ansell, Steven M.; Du, Xinyao; Tam, Yuen Yi C.; Lin, Paulo J. C.; Chen, Sam; Narayanannair, Jayaprakash K.; Rajeev, Kallanthottathil G.; Manoharan, Muthiah; Akinc, Akin; Maier, Martin A.; Cullis, Pieter; Madden, Thomas D.; Hope, Michael J.

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Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2012-01-01

634

OAAI

Belliveau, Nathan M.; Huft, Jens; Lin, Paulo J. C.; Chen, Sam; Leung, Alex K. K.; Leaver, Timothy J.; Wild, Andre W.; Lee, Justin B.; Taylor, Robert J.; Tam, Ying K.; Hansen, Carl L.; Cullis, Pieter R.

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Research Directions