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Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies Mao, Yu-Qian; Jahanshahi, Shahrzad; Malty, Ramy; Van Ommen, David A. J.; Wan, Yimei; Morey, Trevor M.; Chuang, Stephanie H. W.; Pavlova, Veronika; Ahmed, Choudhary; Dahal, Subha; Lin, Funing; Mangos, Maria; Nurtanto, Jocelyn; Song, Yuetong; Been, Terek; Christie-Holmes, Natasha; Gray-Owen, Scott D.; Babu, Mohan; Wong, Amy P.; Batey, Robert A.; Attisano, Liliana; Cochrane, Alan; Houry, Walid A. Share Save
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Evaluating a novel model of hepatitis B care, Hep B PAST, in the Northern Territory of Australia: results from a prospective, population-based study Hosking, Kelly; Binks, Paula; De Santis, Teresa; Wilson, Phillip Merrdi; Gurruwiwi, George Garambaka; Bukulatjpi, Sarah Mariyalawuy; Vintour-Cesar, Emily; Mckinnon, Melita; Nihill, Peter; Fernandes, Tammy-Allyn; Greenwood-Smith, Belinda; Batey, Robert; Ross, Cheryl; Tong, Steven Y. C.; Stewart, Geoffrey; Marshall, Catherine; Gargan, Catherine; Manchikanti, Prashanti; Fuller, Karen; Tate-Baker, Jaclyn; Stewart, Sami; Cowie, Benjamin; Allard, Nicole; Maclachlan, Jennifer H.; Qama, Ashleigh; Boettiger, David; Davis, Joshua S.; Connors, Christine; Davies, Jane Share Save
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High Accuracy Prediction of PROTAC Complex Structures Ignatov, Mikhail; Jindal, Akhil; Kotelnikov, Sergei; Beglov, Dmitri; Posternak, Ganna; Tang, Xiaojing; Maisonneuve, Pierre; Poda, Gennady; Batey, Robert A.; Sicheri, Frank; Whitty, Adrian; Tonge, Peter J.; Vajda, Sandor; Kozakov, Dima Share Save
Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4 Chana, Chetan K.; Maisonneuve, Pierre; Posternak, Ganna; Grinberg, Nicolas G. A.; Poirson, Juline; Ona, Samara M.; Ceccarelli, Derek F.; Mader, Pavel; St-Cyr, Daniel J.; Pau, Victor; Kurinov, Igor; Tang, Xiaojing; Deng, Dongjing; Cui, Weiren; Su, Wenji; Kuai, Letian; Soll, Richard; Tyers, Mike; Rost, Hannes L.; Batey, Robert A.; Taipale, Mikko; Gingras, Anne-Claude; Sicheri, Frank Share Save
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CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding Ackloo, Suzanne; Al-awar, Rima; Amaro, Rommie E.; Arrowsmith, Cheryl H.; Azevedo, Hatylas; Batey, Robert A.; Bengio, Yoshua; Betz, Ulrich A. K.; Bologa, Cristian G.; Chodera, John D.; Cornell, Wendy D.; Dunham, Ian; Ecker, Gerhard F.; Edfeldt, Kristina; Edwards, Aled M.; Gilson, Michael K.; Gordijo, Claudia R.; Hessler, Gerhard; Hillisch, Alexander; Hogner, Anders; Irwin, John J.; Jansen, Johanna M.; Kuhn, Daniel; Leach, Andrew R.; Lee, Alpha A.; Lessel, Uta; Morgan, Maxwell R.; Moult, John; Muegge, Ingo; Oprea, Tudor, I; Perry, Benjamin G.; Riley, Patrick; Rousseaux, Sophie A. L.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Schapira, Matthieu; Scholten, Cora; Todd, Matthew H.; Vedadi, Masoud; Volkamer, Andrea; Willson, Timothy M. Share Save
Development of Antibiotics That Dysregulate the Neisserial ClpP Protease Binepal, Gursonika; Mabanglo, Mark F.; Goodreid, Jordan D.; Leung, Elisa; Barghash, Marim M.; Wong, Keith S.; Lin, Funing; Cossette, Michele; Bansagi, Jazmin; Song, Boxi; Serrao, Vitor Hugo Balasco; Pai, Emil F.; Batey, Robert A.; Gray-Owen, Scott D.; Houry, Walid A. Share Save
Functional characterization of a PROTAC directed against BRAF mutant V600E Posternak, Ganna; Tang, Xiaojing; Maisonneuve, Pierre; Jin, Ting; Lavoie, Hugo; Daou, Salima; Orlicky, Stephen; de Rugy, Theo Goullet; Caldwell, Lauren; Chan, Kin; Aman, Ahmed; Prakesch, Michael; Poda, Gennady; Mader, Pavel; Wong, Cassandra; Maier, Stefan; Kitaygorodsky, Julia; Larsen, Brett; Colwill, Karen; Yin, Zhe; Ceccarelli, Derek F.; Batey, Robert A.; Taipale, Mikko; Kurinov, Igor; Uehling, David; Wrana, Jeff; Durocher, Daniel; Gingras, Anne-Claude; Al-Awar, Rima; Therrien, Marc; Sicheri, Frank Share Save
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ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores Mabanglo, Mark F.; Leung, Elisa; Vahidi, Siavash; Seraphim, Thiago, V; Eger, Bryan T.; Bryson, Steve; Bhandari, Vaibhav; Zhou, Jin Lin; Mao, Yu-Qian; Rizzolo, Kamran; Barghash, Marim M.; Goodreid, Jordan D.; Phanse, Sadhna; Babu, Mohan; Barbosa, Leandro R. S.; Ramos, Carlos H., I; Batey, Robert A.; Kay, Lewis E.; Pai, Emil F.; Houry, Walid A. Share Save
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