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Po‐Ssu Huang

stanford university

38H-index
111Paper Count
1.1WCitation Count
Published Papers 38
Publication Date
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ADAPT-M: a workflow for rapid, quantitative in vitro measurements of enriched protein libraries
errNature Communications
IF15.7
err2026-07-15
err0
errOAAI
errCarla P. Perez; Nicole V. DelRosso; Cameron L. Noland; Udit Parekh; Christian A. Choe; Raphael R. Eguchi; Qi Wen; Polly M. Fordyce; Po-Ssu Huang
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Structural ontogeny of protein-protein interactions
errScience
IF45.8
err2026-02-12
err0
PREAI
errAerin Yang; Hanlun Jiang; Kevin M. Jude; Deniz Akpinaroglu; Stephan Allenspach; Alex Jie Li; James Bowden; Carla Patricia Perez; Liu Liu; Po-Ssu Huang; Tanja Kortemme; Jennifer Listgarten; K. Christopher Garcia
errShare
errSave
High throughput mutational characterization of the GPCR ligand C5a using yeast display and deep sequencing
errStructure
IF4.3
err2025-10-27
err0
PREAI
errYu Xu; Kaushik Thakkar; Li Guan; Yu Miao; Manal Mehibel; Robert B. Lee; David Marciano; Vignesh Viswanathan; Ziwei Wang; Jinglong Wang; Lu Ji; Hongbin Cao; Camille Fisher Petrakian; Jocelyn Valenzuela; Edward LaGory; Xianglian Jia; Eui Jung Moon; Rodolph Martinez; Fang Wu; Richard L. Frock; Everett J. Moding; Quynh-Thu Le; Erinn B. Rankin; Cheng Zhang; Possu Huang; Monica M. Olcina; Amato J. Giaccia; Edward E. Graves
errShare
errSave
Assessing generative model coverage of protein structures with SHAPES
errCell Systems
IF7.7
err2025-07-29
err0
errOAAI
errTianyu Lu; Melissa Liu; Yilin Chen; Jinho Kim; Po-Ssu Huang
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errSave
Targeting peptide antigens using a multiallelic MHC I-binding system
errNATURE BIOTECHNOLOGY
IF41.7
err2024-12-13
err1
errOAAI
errDu, Haotian; Mallik, Leena; Hwang, Daniel; Sun, Yi; Kaku, Chengzi; Hoces, Daniel; Sun, Shirley M.; Ghinnagow, Reem; Carro, Stephen D.; Phan, Hoang Anh T.; Gupta, Sagar; Blackson, Wyatt; Lee, Hyejin; Choe, Christian A.; Dersh, Devin; Liu, Jingjia; Bell, Braxton; Yang, Hongli; Papadaki, Georgia F.; Young, Michael C.; Zhou, Emily; El Nesr, Gina; Goli, Kimia Dasteh; Eisenlohr, Laurence C.; Minn, Andy J.; Hernandez-Lopez, Rogelio A.; Jardine, Joseph G.; Sgourakis, Nikolaos G.; Huang, Po-Ssu
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errSave
A general system for targeting MHC class II-antigen complex via a single adaptable loop
errNATURE BIOTECHNOLOGY
IF41.7
err2024-12-13
err2
PREAI
errDu, Haotian; Liu, Jingjia; Jude, Kevin M.; Yang, Xinbo; Li, Ying; Bell, Braxton; Yang, Hongli; Kassardjian, Audrey; Blackson, Wyatt; Mobedi, Ali; Parekh, Udit; Sperberg, R. Andres Parra; Julien, Jean-Philippe; Mellins, Elizabeth D.; Garcia, K. Christopher; Huang, Po-Ssu
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errSave
An all-atom protein generative model
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-06-25
err3
errOAAI
errChu, Alexander E.; Kim, Jinho; Cheng, Lucy; El Nesr, Gina; Xu, Minkai; Shuai, Richard W.; Huang, Po-Ssu
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errSave
Sparks of function by de novo protein design
errNATURE BIOTECHNOLOGY
IF41.7
err2024-02-15
err9
PREAI
errChu, Alexander E.; Lu, Tianyu; Huang, Po-Ssu
errShare
errSave
A cysteine-specific solubilizing tag strategy enables efficient chemical protein synthesis of difficult targets
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err1
errOAAI
errLi, Wenchao; Jacobsen, Michael T.; Park, Claire; Jung, Jae Un; Lin, Nai-Pin; Huang, Po-Ssu; Lal, Rayhan A.; Chou, Danny Hung-Chieh
errShare
errSave
How can the protein design community best support biologists who want to harness AI tools for protein structure prediction and design?
errCELL SYSTEMS
IF7.7
err2023-08-01
err0
PREAI
errHoecker, Birte; Lu, Peilong; Glasgow, Anum; Marks, Debora S.; Chatterjee, Pranam; Slusky, Joanna S. G.; Schueler-Furman, Ora; Huang, Possu
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errSave
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-06-05
err15
errOAAI
errMindrebo, Laetitia Misson; Liu, Hejun; Ozorowski, Gabriel; Tran, Quoc; Woehl, Jordan; Khalek, Irene; Smith, Jessica M.; Barman, Shawn; Zhao, Fangzhu; Keating, Celina; Limbo, Oliver; Verma, Megan; Liu, Jingjia; Stanfield, Robyn L.; Zhu, Xueyong; Turner, Hannah L.; Sok, Devin; Huang, Po-Ssu; Burton, Dennis R.; Ward, Andrew B.; Wilson, Ian A.; Jardine, Joseph G.
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errSave
Ig-VAE: Generative modeling of protein structure by direct 3D coordinate generation
errplos biology
IF3.6
err2022-06-27
err62
errOAAI
errEguchi, Raphael R.; Choe, Christian A.; Huang, Po-Ssu
errShare
errSave
Interleukin-2 superkines by computational design
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-03-16
err13
errOAAI
errRen, Junming; Chu, Alexander E.; Jude, Kevin M.; Picton, Lora K.; Kare, Aris J.; Su, Leon; Romero, Alejandra Montano; Huang, Po-Ssu; Garcia, K. Christopher
errShare
errSave
Chimeric mutants of staphylococcal hemolysin, which act as both one-component and two-component hemolysin, created by grafting the stem domain
errFEBS JOURNAL
IF4.2
err2022-02-16
err2
PREAI
errGhanem, Nouran; Kanagami, Natsuki; Matsui, Takashi; Takeda, Kein; Kaneko, Jun; Shiraishi, Yasuyuki; Choe, Christian A.; Uchikubo-Kamo, Tomomi; Shirouzu, Mikako; Hashimoto, Tsubasa; Ogawa, Tomohisa; Matsuura, Tomoaki; Huang, Po-Ssu; Yokoyama, Takeshi; Tanaka, Yoshikazu
errShare
errSave
Protein sequence design with a learned potential
errNATURE COMMUNICATIONS
IF15.7
err2022-02-08
err86
errOAAI
errAnand, Namrata; Eguchi, Raphael; Mathews, Irimpan I.; Perez, Carla P.; Derry, Alexander; Altman, Russ B.; Huang, Po-Ssu
errShare
errSave
Structure-based protein design with deep learning
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2021-12-01
err57
errOAAI
errOvchinnikov, Sergey; Huang, Po-Ssu
errShare
errSave
Theoretical basis for stabilizing messenger RNA through secondary structure design (vol 49, pg 10604, 2021)
errNUCLEIC ACIDS RESEARCH
IF13.1
err2021-09-30
err4
errOAAI
errWayment-Steele, Hannah K.; Kim, Do Soon; Choe, Christian A.; Nicol, John J.; Wellington-Oguri, Roger; Watkins, Andrew M.; Sperberg, R. Andres Parra; Huang, Po-Ssu; Participants, Eterna; Das, Rhiju
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errSave
Theoretical basis for stabilizing messenger RNA through secondary structure design
errNUCLEIC ACIDS RESEARCH
IF13.1
err2021-09-14
err86
errOAAI
errWayment-Steele, Hannah K.; Kim, Do Soon; Choe, Christian A.; Nicol, John J.; Wellington-Oguri, Roger; Watkins, Andrew M.; Sperberg, R. Andres Parra; Huang, Po-Ssu; Participants, Eterna; Das, Rhiju
errShare
errSave
Optical control of fast and processive engineered myosins in vitro and in living cells
errNATURE CHEMICAL BIOLOGY
IF13.7
err2021-02-18
err16
PREAI
errRuijgrok, Paul V.; Ghosh, Rajarshi P.; Zemsky, Sasha; Nakamura, Muneaki; Gong, Rui; Ning, Lin; Chen, Robert; Vachharajani, Vipul T.; Chu, Alexander E.; Anand, Namrata; Eguchi, Raphael R.; Huang, Po-Ssu; Lin, Michael Z.; Alushin, Gregory M.; Liphardt, Jan T.; Bryant, Zev
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Identification of N-Terminally Diversified GLP-1R Agonists Using Saturation Mutagenesis and Chemical Design
errACS CHEMICAL BIOLOGY
IF3.8
err2020-12-14
err7
errOAAI
errLongwell, Chelsea K.; Hanna, Stephanie; Hartrampf, Nina; Sperberg, R. Andres Parra; Huang, Po-Ssu; Pentelute, Bradley L.; Cochran, Jennifer R.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
I
Ian A. Wilson
H-index: 179 · Papers: 1.7K
D
Dennis R. Burton
H-index: 172 · Papers: 800
T
Timothy A. Springer
H-index: 165 · Papers: 734
D
David C. Montefiori
H-index: 142 · Papers: 1.2K
J
John P. Moore
H-index: 132 · Papers: 572
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