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W

Wesley R. Legant

University of North Carolina

32H-index
93Paper Count
1.1WCitation Count
Published Papers 37
Publication Date
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A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms
errNature Methods
IF32.1
err2026-05-22
err0
errOAAI
errTian-Ming Fu; Gaoxiang Liu; Daniel E. Milkie; Xiongtao Ruan; Frederik Görlitz; Yu Shi; Valentina Ferro; Nikita S. Divekar; Wei Wang; Harrison M. York; Velat Kilic; Matthew Mueller; Yajie Liang; Timothy A. Daugird; Maria Jose Gacha-Garay; Kathryn A. Larkin; Rebecca C. Adikes; Nathanael Harrison; Cyna Shirazinejad; Samara Williams; Jamison L. Nourse; Shu-Hsien Sheu; Liang Gao; Tongchao Li; Chandrani Mondal; Kemal Achour; Wilmene Hercule; Daniel R. Stabley; Kevin Emmerich; Peng Dong; David G. Drubin; Zhe J. Liu; Jeff S. Mumm; Minoru Koyama; Alison N. Killilea; Jose Javier Bravo-Cordero; C. Dirk Keene; Liqun Luo; Tomas Kirchhausen; Medha M. Pathak; Senthil Arumugam; James K. Nuñez; Ruixuan Gao; David Q. Matus; Benjamin L. Martin; Ian A. Swinburne; Eric Betzig; Wesley R. Legant; Srigokul Upadhyayula
errShare
errSave
Feasibility of deep learning-based cancer detection in ultrasound microvascular images
errUltrasonics
IF4.1
err2025-11-15
err0
PREAI
errKathlyne Jayne B. Bautista; Thomas M. Kierski; Isabel G. Newsome; Hae Rim Lee; Wesley R. Legant; David S. Lalush; Paul A. Dayton
errShare
errSave
Shared and redundant proteins coordinate signal cross-talk between MAPK pathways in yeast
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2024-10-01
err0
PREAI
errZhang, Shu; Wang, Hao; Sipko, Emily L.; Li, Shuang; Daugird, Timothy A.; Legant, Wesley R.; Dohlman, Henrik G.
errShare
errSave
Cell dynamics revealed by microscopy advances
errCURRENT OPINION IN CELL BIOLOGY
IF4.3
err2024-10-01
err1
PREAI
errHockenberry, Max A.; Daugird, Timothy A.; Legant, Wesley R.
errShare
errSave
Posterior approach to correct for focal plane offsets in lattice light-sheet structured illumination microscopy
errJOURNAL OF BIOMEDICAL OPTICS
IF2.9
err2024-07-31
err0
errOAAI
errShi, Yu; Daugird, Tim A.; Legant, Wesley R.
errShare
errSave
Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment
errNATURE COMMUNICATIONS
IF15.7
err2024-05-16
err3
errOAAI
errDaugird, Timothy A.; Shi, Yu; Holland, Katie L.; Rostamian, Hosein; Liu, Zhe; Lavis, Luke D.; Rodriguez, Joseph; Strahl, Brian D.; Legant, Wesley R.
errShare
errSave
Smart lattice light-sheet microscopy for imaging rare and complex cellular events
errNATURE METHODS
IF32.1
err2024-01-02
err12
errOAAI
errShi, Yu; Tabet, Jimmy S.; Milkie, Daniel E.; Daugird, Timothy A.; Yang, Chelsea Q.; Ritter, Alex T.; Giovannucci, Andrea; Legant, Wesley R.
errShare
errSave
u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions
errCELL REPORTS METHODS
IF4.5
err2023-12-01
err10
errOAAI
errRoudot, Philippe; Legant, Wesley R.; Zou, Qiongjing; Dean, Kevin M.; Isogai, Tadamoto; Welf, Erik S.; David, Ana F.; Gerlich, Daniel W.; Fiolka, Reto; Betzig, Eric; Danuser, Gaudenz
errShare
errSave
Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics
errACTA BIOMATERIALIA
IF9.6
err2023-08-01
err2
errOAAI
errDoherty, Elizabeth L.; Aw, Wen Yih; Warren, Emily C.; Hockenberry, Max; Whitworth, Chloe P.; Krohn, Grace; Howell, Stefanie; Diekman, Brian O.; Legant, Wesley R.; Nia, Hadi Tavakoli; Hickey, Anthony J.; Polacheck, William J.
errShare
errSave
A Photopolymerized Hydrogel System with Dual Stiffness Gradients Reveals Distinct Actomyosin-Based Mechano-Responses in Fibroblast Durotaxis
errACS NANO
IF16
err2022-12-07
err7
errOAAI
errHakeem, Reem M.; Subramanian, Bhagawat C.; Hockenberry, Max A.; King, Zayna T.; Butler, Mitchell T.; Legant, Wesley R.; Bear, James E.
errShare
errSave
Cells in the mechanical spotlight
errBIOPHYSICAL JOURNAL
IF3.1
err2022-10-01
err0
errOAAI
errHockenberry, Max A.; Legant, Wesley R.
errShare
errSave
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2022-09-15
err2
errOAAI
errMoore, Regan P.; Fogerson, Stephanie M.; Tulu, U. Serdar; Yu, Jason W.; Cox, Amanda H.; Sican, Melissa A.; Li, Dong; Legant, Wesley R.; Weigel, Aubrey, V; Crawford, Janice M.; Betzig, Eric; Kiehart, Daniel P.
errShare
errSave
A quantitative analysis of various patterns applied in lattice light sheet microscopy
errNATURE COMMUNICATIONS
IF15.7
err2022-08-08
err16
errOAAI
errShi, Yu; Daugird, Timothy A.; Legant, Wesley R.
errShare
errSave
Coro1B and Coro1C regulate lamellipodia dynamics and cell motility by tuning branched actin turnover
errJOURNAL OF CELL BIOLOGY
IF6.4
err2022-06-03
err10
errOAAI
errKing, Zayna T.; Butler, Mitchell T.; Hockenberry, Max A.; Subramanian, Bhagawat C.; Siesser, Priscila F.; Graham, David M.; Legant, Wesley R.; Bear, James E.
errShare
errSave
A multi-functional microfluidic device compatible with widefield and light sheet microscopy
errLAB ON A CHIP
IF5.4
err2022-01-01
err6
errOAAI
errMoore, Regan P.; O'Shaughnessy, Ellen C.; Shi, Yu; Nogueira, Ana T.; Heath, Katelyn M.; Hahn, Klaus M.; Legant, Wesley R.
errShare
errSave
Deep learning enables fast and dense single-molecule localization with high accuracy (vol 18, pg 1082, 2021)
errNATURE METHODS
IF32.1
err2021-09-21
err0
errOAAI
errSpeiser, Artur; Muller, Lucas-Raphael; Hoess, Philipp; Matti, Ulf; Obara, Christopher J.; Legant, Wesley R.; Kreshuk, Anna; Macke, Jakob H.; Ries, Jonas; Turaga, Srinivas C.
errShare
errSave
Deep learning enables fast and dense single-molecule localization with high accuracy
errNATURE METHODS
IF32.1
err2021-09-03
err131
errOAAI
errSpeiser, Artur; Mueller, Lucas-Raphael; Hoess, Philipp; Matti, Ulf; Obara, Christopher J.; Legant, Wesley R.; Kreshuk, Anna; Macke, Jakob H.; Ries, Jonas; Turaga, Srinivas C.
errShare
errSave
3D ATAC-PALM: super-resolution imaging of the accessible genome
errNATURE METHODS
IF32.1
err2020-03-16
err59
errOAAI
errXie, Liangqi; Dong, Peng; Chen, Xingqi; Hsieh, Tsung-Han S.; Banala, Sambashiva; De Marzio, Margherita; English, Brian P.; Qi, Yifeng; Jung, Seol Kyoung; Kieffer-Kwon, Kyong-Rim; Legant, Wesley R.; Hansen, Anders S.; Schulmann, Anton; Casellas, Rafael; Zhang, Bin; Betzig, Eric; Lavis, Luke D.; Chang, Howard Y.; Tjian, Robert; Liu, Zhe
errShare
errSave
Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor
errJOURNAL OF CELL BIOLOGY
IF6.4
err2019-08-23
err28
errOAAI
errO'Shaughnessy, Ellen C.; Stone, Orrin J.; LaFosse, Paul K.; Azoitei, Mihai L.; Tsygankov, Denis; Heddleston, John M.; Legant, Wesley R.; Wittchen, Erika S.; Burridge, Keith; Elston, Timothy C.; Betzig, Eric; Chew, Teng-Leong; Adalsteinsson, David; Hahn, Klaus M.
errShare
errSave
High-resolution imaging reveals how the spindle midzone impacts chromosome movement
errJOURNAL OF CELL BIOLOGY
IF6.4
err2019-06-27
err46
errOAAI
errPamula, Melissa C.; Carlini, Lina; Forth, Scott; Verma, Priyanka; Suresh, Subbulakshmi; Legant, Wesley R.; Khodjakoy, Alexey; Betzig, Eric; Kapoor, Tarun M.
errShare
errSave

Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
H
Howard Y. Chang
H-index: 162 · Papers: 737
R
Robert Tjian
H-index: 150 · Papers: 479
J
Jennifer Lippincott‐Schwartz
H-index: 134 · Papers: 444
J
Jason A. Burdick
H-index: 128 · Papers: 521
C
Christopher S. Chen
H-index: 125 · Papers: 719
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